STRINGSTRING
pola2 pola2 rad9a rad9a ENSMAMP00000003022 ENSMAMP00000003022 pole4 pole4 ENSMAMP00000006136 ENSMAMP00000006136 rfc5 rfc5 pole2 pole2 rfc4 rfc4 ENSMAMP00000011414 ENSMAMP00000011414 ENSMAMP00000013291 ENSMAMP00000013291 cdca7l cdca7l ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 ENSMAMP00000021732 ENSMAMP00000021732 pole pole ENSMAMP00000022264 ENSMAMP00000022264 pcna pcna prim2 prim2 recql4 recql4 wdhd1 wdhd1 pole3 pole3 rad17 rad17 ENSMAMP00000029947 ENSMAMP00000029947 DNA2 DNA2 hus1 hus1 fen1 fen1 pola1 pola1 ENSMAMP00000035212 ENSMAMP00000035212 prim1 prim1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
ENSMAMP00000003022Uncharacterized protein. (510 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa)
ENSMAMP00000006136Zgc:110269. (348 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
ENSMAMP00000011414Exonuclease 1. (740 aa)
ENSMAMP00000013291DNA ligase. (987 aa)
cdca7lCell division cycle associated 7b. (409 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
ENSMAMP00000022264RAD1 homolog (S. pombe). (332 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (540 aa)
recql4RecQ helicase-like 4. (1548 aa)
wdhd1WD repeat and HMG-box DNA binding protein 1. (1123 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa)
rad17RAD17 checkpoint clamp loader component. (636 aa)
ENSMAMP00000029947Replication factor C subunit 1. (1137 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (315 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
pola1DNA polymerase. (1480 aa)
ENSMAMP00000035212ATPase family AAA domain containing 5a. (1802 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.