15 items (Mastacembelus armatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mlx	MAX dimerization protein MLX. (246 aa)
	insig1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (260 aa)
	ENSMAMP00000007982	Niemann-Pick disease, type C2. (162 aa)
	ENSMAMP00000008188	Patched domain containing 4. (911 aa)
	LOC113143393	BHLH domain-containing protein. (957 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1302 aa)
	srebf2	Sterol regulatory element binding transcription factor 2. (1175 aa)
	ppargc1b	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (935 aa)
	ptchd1	Patched domain containing 1. (982 aa)
	scap	SREBF chaperone. (1273 aa)
	LOC113132615	Membrane-bound transcription factor peptidase, site 1. (1086 aa)
	mxd4	MAX dimerization protein 4. (210 aa)
	npc1	Niemann-Pick disease, type C1. (1271 aa)
	mlxip	MLX interacting protein. (857 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1226 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMAMP00000007982	ENSMAMP00000008188	ENSMAMP00000007982	ENSMAMP00000008188	Niemann-Pick disease, type C2.	Patched domain containing 4.	0.626
ENSMAMP00000007982	NPC1L1	ENSMAMP00000007982	ENSMAMP00000010751	Niemann-Pick disease, type C2.	NPC1 like intracellular cholesterol transporter 1.	0.988
ENSMAMP00000007982	npc1	ENSMAMP00000007982	ENSMAMP00000025546	Niemann-Pick disease, type C2.	Niemann-Pick disease, type C1.	0.990
ENSMAMP00000007982	ptchd1	ENSMAMP00000007982	ENSMAMP00000017826	Niemann-Pick disease, type C2.	Patched domain containing 1.	0.626
ENSMAMP00000007982	scap	ENSMAMP00000007982	ENSMAMP00000017879	Niemann-Pick disease, type C2.	SREBF chaperone.	0.964
ENSMAMP00000008188	ENSMAMP00000007982	ENSMAMP00000008188	ENSMAMP00000007982	Patched domain containing 4.	Niemann-Pick disease, type C2.	0.626
ENSMAMP00000008188	NPC1L1	ENSMAMP00000008188	ENSMAMP00000010751	Patched domain containing 4.	NPC1 like intracellular cholesterol transporter 1.	0.504
ENSMAMP00000008188	npc1	ENSMAMP00000008188	ENSMAMP00000025546	Patched domain containing 4.	Niemann-Pick disease, type C1.	0.504
LOC113132615	NPC1L1	ENSMAMP00000023158	ENSMAMP00000010751	Membrane-bound transcription factor peptidase, site 1.	NPC1 like intracellular cholesterol transporter 1.	0.604
LOC113132615	npc1	ENSMAMP00000023158	ENSMAMP00000025546	Membrane-bound transcription factor peptidase, site 1.	Niemann-Pick disease, type C1.	0.604
LOC113132615	scap	ENSMAMP00000023158	ENSMAMP00000017879	Membrane-bound transcription factor peptidase, site 1.	SREBF chaperone.	0.814
LOC113132615	srebf1	ENSMAMP00000023158	ENSMAMP00000035045	Membrane-bound transcription factor peptidase, site 1.	Sterol regulatory element binding transcription factor 1.	0.760
LOC113132615	srebf2	ENSMAMP00000023158	ENSMAMP00000012084	Membrane-bound transcription factor peptidase, site 1.	Sterol regulatory element binding transcription factor 2.	0.760
LOC113143393	mlx	ENSMAMP00000008853	ENSMAMP00000001639	BHLH domain-containing protein.	MAX dimerization protein MLX.	0.982
LOC113143393	ppargc1b	ENSMAMP00000008853	ENSMAMP00000014689	BHLH domain-containing protein.	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta.	0.849
LOC113143393	srebf1	ENSMAMP00000008853	ENSMAMP00000035045	BHLH domain-containing protein.	Sterol regulatory element binding transcription factor 1.	0.418
LOC113143393	srebf2	ENSMAMP00000008853	ENSMAMP00000012084	BHLH domain-containing protein.	Sterol regulatory element binding transcription factor 2.	0.418
NPC1L1	ENSMAMP00000007982	ENSMAMP00000010751	ENSMAMP00000007982	NPC1 like intracellular cholesterol transporter 1.	Niemann-Pick disease, type C2.	0.988
NPC1L1	ENSMAMP00000008188	ENSMAMP00000010751	ENSMAMP00000008188	NPC1 like intracellular cholesterol transporter 1.	Patched domain containing 4.	0.504
NPC1L1	LOC113132615	ENSMAMP00000010751	ENSMAMP00000023158	NPC1 like intracellular cholesterol transporter 1.	Membrane-bound transcription factor peptidase, site 1.	0.604