(12 nodes) Sir2 family, and ADP-ribosyl cyclase network (Mastacembelus armatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	LOC113132980	Si:dkey-103i16.6. (442 aa)
	nampt	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
	sirt6	Sirtuin 6. (348 aa)
	ENSMAMP00000016353	Uncharacterized protein. (239 aa)
	LOC113121744	Uncharacterized protein. (277 aa)
	sirt7	Sirtuin 7. (406 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (383 aa)
	sirt5	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (305 aa)
	LOC113134951	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (305 aa)
	sirt3	Sirtuin 3. (629 aa)
	nmnat2	Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (309 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMAMP00000016353	LOC113132980	ENSMAMP00000016353	ENSMAMP00000009510	Uncharacterized protein.	Si:dkey-103i16.6.	0.842
ENSMAMP00000016353	LOC113134951	ENSMAMP00000016353	ENSMAMP00000021220	Uncharacterized protein.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.834
ENSMAMP00000016353	nampt	ENSMAMP00000016353	ENSMAMP00000013677	Uncharacterized protein.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.862
ENSMAMP00000016353	nmnat2	ENSMAMP00000016353	ENSMAMP00000027822	Uncharacterized protein.	Nicotinamide nucleotide adenylyltransferase 2.	0.846
ENSMAMP00000016353	sirt2	ENSMAMP00000016353	ENSMAMP00000018711	Uncharacterized protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.834
ENSMAMP00000016353	sirt3	ENSMAMP00000016353	ENSMAMP00000026766	Uncharacterized protein.	Sirtuin 3.	0.842
ENSMAMP00000016353	sirt4	ENSMAMP00000016353	ENSMAMP00000035261	Uncharacterized protein.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.834
ENSMAMP00000016353	sirt5	ENSMAMP00000016353	ENSMAMP00000021103	Uncharacterized protein.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.834
ENSMAMP00000016353	sirt6	ENSMAMP00000016353	ENSMAMP00000013820	Uncharacterized protein.	Sirtuin 6.	0.835
ENSMAMP00000016353	sirt7	ENSMAMP00000016353	ENSMAMP00000016918	Uncharacterized protein.	Sirtuin 7.	0.834
LOC113121744	LOC113132980	ENSMAMP00000016374	ENSMAMP00000009510	Uncharacterized protein.	Si:dkey-103i16.6.	0.842
LOC113121744	LOC113134951	ENSMAMP00000016374	ENSMAMP00000021220	Uncharacterized protein.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.834
LOC113121744	nampt	ENSMAMP00000016374	ENSMAMP00000013677	Uncharacterized protein.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.862
LOC113121744	nmnat2	ENSMAMP00000016374	ENSMAMP00000027822	Uncharacterized protein.	Nicotinamide nucleotide adenylyltransferase 2.	0.846
LOC113121744	sirt2	ENSMAMP00000016374	ENSMAMP00000018711	Uncharacterized protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.834
LOC113121744	sirt3	ENSMAMP00000016374	ENSMAMP00000026766	Uncharacterized protein.	Sirtuin 3.	0.842
LOC113121744	sirt4	ENSMAMP00000016374	ENSMAMP00000035261	Uncharacterized protein.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.834
LOC113121744	sirt5	ENSMAMP00000016374	ENSMAMP00000021103	Uncharacterized protein.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.834
LOC113121744	sirt6	ENSMAMP00000016374	ENSMAMP00000013820	Uncharacterized protein.	Sirtuin 6.	0.835
LOC113121744	sirt7	ENSMAMP00000016374	ENSMAMP00000016918	Uncharacterized protein.	Sirtuin 7.	0.834