(70 nodes) Positive regulation of developmental growth network (Mastacembelus armatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	LOC113139179	Si:dkey-40c11.2. (778 aa)
	LOC113124594	Drebrin-like a. (495 aa)
	LOC113135984	Synaptotagmin Vb. (425 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (500 aa)
	LOC113146281	Colony stimulating factor 1b (macrophage). (271 aa)
	zfyve27	Zinc finger, FYVE domain containing 27. (415 aa)
	LOC113136312	Si:ch211-113g11.6; Belongs to the semaphorin family. (639 aa)
	CDKL5	Cyclin dependent kinase like 5. (1041 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	agrn	Agrin. (2075 aa)
	bbs4	Bardet-Biedl syndrome 4. (538 aa)
	LOC113123099	Fibronectin 1a. (2504 aa)
	ENSMAMP00000021824	RUN and SH3 domain containing 1. (737 aa)
	ENSMAMP00000022853	Synaptotagmin Ia. (418 aa)
	ENSMAMP00000023341	Insulin-like growth factor 1. (161 aa)
	LOC113136028	Rho family GTPase 2. (230 aa)
	ENSMAMP00000024140	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
	ENSMAMP00000024260	Uncharacterized protein. (320 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	srf	Serum response factor b. (601 aa)
	LOC113145880	Activity-dependent neuroprotector homeobox b. (1058 aa)
	disc1	DISC1 scaffold protein. (852 aa)
	LOC113123821	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1252 aa)
	SRF	Serum response factor. (519 aa)
	dbn1	Drebrin 1. (565 aa)
	ENSMAMP00000033381	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (445 aa)
	golga4	Golgin A4. (2068 aa)
	sash3	SAM and SH3 domain containing 3. (406 aa)
	ENSMAMP00000029376	NMDA receptor synaptonuclear signaling and neuronal migration factor b. (597 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (814 aa)
	mkks	McKusick-Kaufman syndrome. (568 aa)
	ENSMAMP00000026150	Spastin; Belongs to the AAA ATPase family. (484 aa)
	LOC113140879	Rho family GTPase 2. (234 aa)
	ENSMAMP00000000040	Uncharacterized protein. (1414 aa)
	ENSMAMP00000005046	Zinc finger protein, FOG family member 2a. (1210 aa)
	rnf157	Ring finger protein 157. (701 aa)
	rufy3	RUN and FYVE domain containing 3. (664 aa)
	ist1	IST1 factor associated with ESCRT-III. (392 aa)
	ENSMAMP00000001804	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	ENSMAMP00000000041	A kinase (PRKA) anchor protein 6. (1040 aa)
	ENSMAMP00000006422	Mitochondrial E3 ubiquitin protein ligase 1b. (345 aa)
	LOC113130585	Uncharacterized protein. (430 aa)
	edn1	Endothelin 1. (204 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (380 aa)
	LOC113122494	Uncharacterized protein; Belongs to the semaphorin family. (626 aa)
	l1cam	L1 cell adhesion molecule, paralog a. (1279 aa)
	plaa	Phospholipase A2-activating protein. (798 aa)
	LOC113135299	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	LOC113135111	Parvalbumin 9; Belongs to the parvalbumin family. (113 aa)
	islr2	Immunoglobulin superfamily containing leucine-rich repeat 2. (714 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (651 aa)
	shtn1	Shootin 1. (516 aa)
	LOC113145533	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
	ENSMAMP00000011715	ZP domain-containing protein. (410 aa)
	ENSMAMP00000011867	NMDA receptor synaptonuclear signaling and neuronal migration factor a. (638 aa)
	nol12	Nucleolar protein 12. (234 aa)
	parp2	Poly [ADP-ribose] polymerase. (649 aa)
	LOC113146195	Uncharacterized protein. (1289 aa)
	LOC113133177	Uncharacterized protein. (186 aa)
	LOC113145539	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (288 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
	dbnl	Drebrin-like b. (477 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1065 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (826 aa)
	ENSMAMP00000015647	Cyclin-dependent kinase-like 5. (1071 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	LOC113140921	Parvalbumin 8; Belongs to the parvalbumin family. (117 aa)
	ENSMAMP00000035302	Uncharacterized protein. (201 aa)
	LOC113145471	Synaptotagmin IIa. (432 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMAMP00000001804	edn1	ENSMAMP00000001804	ENSMAMP00000006803	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.914
ENSMAMP00000006422	ENSMAMP00000033381	ENSMAMP00000006422	ENSMAMP00000033381	Mitochondrial E3 ubiquitin protein ligase 1b.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.437
ENSMAMP00000023341	ENSMAMP00000024260	ENSMAMP00000023341	ENSMAMP00000024260	Insulin-like growth factor 1.	Uncharacterized protein.	0.566
ENSMAMP00000023341	LOC113123821	ENSMAMP00000023341	ENSMAMP00000025857	Insulin-like growth factor 1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.587
ENSMAMP00000023341	LOC113133177	ENSMAMP00000023341	ENSMAMP00000012617	Insulin-like growth factor 1.	Uncharacterized protein.	0.507
ENSMAMP00000023341	LOC113145539	ENSMAMP00000023341	ENSMAMP00000012672	Insulin-like growth factor 1.	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.499
ENSMAMP00000023341	bmpr2	ENSMAMP00000023341	ENSMAMP00000015001	Insulin-like growth factor 1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.587
ENSMAMP00000023341	igf2	ENSMAMP00000023341	ENSMAMP00000005327	Insulin-like growth factor 1.	Insulin-like growth factor 2b.	0.930
ENSMAMP00000023341	islr2	ENSMAMP00000023341	ENSMAMP00000010384	Insulin-like growth factor 1.	Immunoglobulin superfamily containing leucine-rich repeat 2.	0.566
ENSMAMP00000024140	LOC113145533	ENSMAMP00000024140	ENSMAMP00000011627	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.490
ENSMAMP00000024140	smo	ENSMAMP00000024140	ENSMAMP00000015610	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.552
ENSMAMP00000024140	wnt2b	ENSMAMP00000024140	ENSMAMP00000012787	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.490
ENSMAMP00000024260	ENSMAMP00000023341	ENSMAMP00000024260	ENSMAMP00000023341	Uncharacterized protein.	Insulin-like growth factor 1.	0.566
ENSMAMP00000026150	ist1	ENSMAMP00000026150	ENSMAMP00000002282	Spastin; Belongs to the AAA ATPase family.	IST1 factor associated with ESCRT-III.	0.946
ENSMAMP00000026150	plaa	ENSMAMP00000026150	ENSMAMP00000009082	Spastin; Belongs to the AAA ATPase family.	Phospholipase A2-activating protein.	0.736
ENSMAMP00000026150	zfyve27	ENSMAMP00000026150	ENSMAMP00000018196	Spastin; Belongs to the AAA ATPase family.	Zinc finger, FYVE domain containing 27.	0.519
ENSMAMP00000033381	ENSMAMP00000006422	ENSMAMP00000033381	ENSMAMP00000006422	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Mitochondrial E3 ubiquitin protein ligase 1b.	0.437
ENSMAMP00000033381	LOC113123099	ENSMAMP00000033381	ENSMAMP00000021343	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Fibronectin 1a.	0.468
ENSMAMP00000033381	LOC113123821	ENSMAMP00000033381	ENSMAMP00000025857	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.405
ENSMAMP00000033381	LOC113136028	ENSMAMP00000033381	ENSMAMP00000023735	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Rho family GTPase 2.	0.573