(18 nodes) I-SMAD binding network (Mastacembelus armatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	LOC113138813	Mothers against decapentaplegic homolog. (510 aa)
	axin1	Axin 1. (870 aa)
	LOC113144295	Mothers against decapentaplegic homolog. (478 aa)
	smad2	Mothers against decapentaplegic homolog. (474 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	smad6	Mothers against decapentaplegic homolog. (491 aa)
	AXIN2	Axin 2. (792 aa)
	ENSMAMP00000010117	Uncharacterized protein. (887 aa)
	ints8	Integrator complex subunit 8. (995 aa)
	SMAD4	Mothers against decapentaplegic homolog. (503 aa)
	LOC113137780	Mothers against decapentaplegic homolog. (502 aa)
	smad1	Mothers against decapentaplegic homolog. (467 aa)
	smad9	Mothers against decapentaplegic homolog. (468 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	LOC113126055	Mothers against decapentaplegic homolog. (617 aa)
	LOC113138457	Mothers against decapentaplegic homolog. (467 aa)
	LOC113141573	Axin 2 (conductin, axil). (842 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSMAMP00000010117	ENSMAMP00000009247	ENSMAMP00000010117	Axin 2.	Uncharacterized protein.	0.853
AXIN2	LOC113141573	ENSMAMP00000009247	ENSMAMP00000034887	Axin 2.	Axin 2 (conductin, axil).	0.843
AXIN2	axin1	ENSMAMP00000009247	ENSMAMP00000003308	Axin 2.	Axin 1.	0.853
ENSMAMP00000010117	AXIN2	ENSMAMP00000010117	ENSMAMP00000009247	Uncharacterized protein.	Axin 2.	0.853
ENSMAMP00000010117	LOC113141573	ENSMAMP00000010117	ENSMAMP00000034887	Uncharacterized protein.	Axin 2 (conductin, axil).	0.853
LOC113126055	LOC113137780	ENSMAMP00000030369	ENSMAMP00000017959	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.620
LOC113126055	LOC113138457	ENSMAMP00000030369	ENSMAMP00000030452	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.942
LOC113126055	LOC113138813	ENSMAMP00000030369	ENSMAMP00000001989	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.842
LOC113126055	LOC113144295	ENSMAMP00000030369	ENSMAMP00000005178	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.960
LOC113126055	SMAD3	ENSMAMP00000030369	ENSMAMP00000017997	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.942
LOC113126055	SMAD4	ENSMAMP00000030369	ENSMAMP00000017781	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.843
LOC113126055	ints8	ENSMAMP00000030369	ENSMAMP00000010606	Mothers against decapentaplegic homolog.	Integrator complex subunit 8.	0.859
LOC113126055	smad1	ENSMAMP00000030369	ENSMAMP00000021007	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.960
LOC113126055	smad2	ENSMAMP00000030369	ENSMAMP00000007952	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.942
LOC113126055	smad3	ENSMAMP00000030369	ENSMAMP00000008800	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.942
LOC113126055	smad6	ENSMAMP00000030369	ENSMAMP00000008827	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.620
LOC113126055	smad7	ENSMAMP00000030369	ENSMAMP00000022079	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.620
LOC113126055	smad9	ENSMAMP00000030369	ENSMAMP00000021061	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.960
LOC113137780	LOC113126055	ENSMAMP00000017959	ENSMAMP00000030369	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.620
LOC113137780	LOC113138457	ENSMAMP00000017959	ENSMAMP00000030452	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.746