(64 nodes) Catalytic step 2 spliceosome network (Mastacembelus armatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lsm7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (806 aa)
	ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (193 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (980 aa)
	dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1256 aa)
	cdc40	Cell division cycle 40 homolog (S. cerevisiae). (581 aa)
	rbmx	RNA binding motif protein X-linked. (393 aa)
	cwc22	CWC22 spliceosome associated protein homolog. (1007 aa)
	ENSMAMP00000027440	Uncharacterized protein. (131 aa)
	ENSMAMP00000009238	DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1211 aa)
	ENSMAMP00000009605	Splicing factor 3a, subunit 1. (805 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	ENSMAMP00000010651	Uncharacterized protein. (229 aa)
	ENSMAMP00000010653	WD_REPEATS_REGION domain-containing protein. (208 aa)
	rbm22	RNA binding motif protein 22. (427 aa)
	ENSMAMP00000011379	Splicing factor 3b, subunit 6. (110 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2144 aa)
	LOC113127052	Synaptotagmin binding, cytoplasmic RNA interacting protein, like. (609 aa)
	snw1	SNW domain containing 1. (537 aa)
	crnkl1	Crooked neck pre-mRNA splicing factor 1. (758 aa)
	prpf8	Pre-mRNA processing factor 8. (2338 aa)
	ENSMAMP00000013700	Small nuclear ribonucleoprotein-associated protein. (246 aa)
	LOC113130904	ISY1 splicing factor homolog. (283 aa)
	plrg1	Pleiotropic regulator 1. (511 aa)
	sf3a2	Splicing factor 3a, subunit 2. (296 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (130 aa)
	srrm1	Serine/arginine repetitive matrix 1. (863 aa)
	sf3b1	Splicing factor 3b, subunit 1. (1331 aa)
	syf2	SYF2 pre-mRNA-splicing factor. (244 aa)
	snrpa1	Small nuclear ribonucleoprotein polypeptide A. (288 aa)
	dhx35	DEAH-box helicase 35. (699 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (975 aa)
	prpf4b	Pre-mRNA processing factor 4Bb. (1015 aa)
	ess2	Ess-2 splicing factor homolog. (474 aa)
	DDX41	DEAD-box helicase 41. (614 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	ENSMAMP00000017334	Zgc:153119. (326 aa)
	sart1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (774 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	pnn	Pinin, desmosome associated protein. (679 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	xab2	XPA binding protein 2. (848 aa)
	cwc15	CWC15 spliceosome associated protein homolog. (237 aa)
	bcas2	BCAS2 pre-mRNA processing factor. (225 aa)
	ENSMAMP00000026527	Zinc finger, CCHC domain containing 8. (605 aa)
	ENSMAMP00000025003	Mtr4 exosome RNA helicase. (1018 aa)
	ENSMAMP00000024876	Small nuclear ribonucleoprotein polypeptide F. (85 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	ppil2	Peptidylprolyl isomerase (cyclophilin)-like 2. (526 aa)
	ENSMAMP00000020979	DEAH (Asp-Glu-Ala-His) box polypeptide 34. (1172 aa)
	sf3b2	Splicing factor 3b, subunit 2. (878 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1470 aa)
	LOC113129167	Heterogeneous nuclear ribonucleoprotein M. (709 aa)
	ENSMAMP00000007615	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (173 aa)
	cwc27	CWC27 spliceosome associated cyclophilin. (479 aa)
	ppwd1	Peptidylprolyl isomerase domain and WD repeat containing 1. (628 aa)
	LOC113131235	Uncharacterized protein. (625 aa)
	ENSMAMP00000005952	annotation not available (338 aa)
	wdr83	WD repeat domain containing 83. (317 aa)
	sf3a3	Splicing factor 3a, subunit 3. (501 aa)
	hnrnpr	Heterogeneous nuclear ribonucleoprotein R. (620 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX41	ENSMAMP00000007615	ENSMAMP00000016606	ENSMAMP00000007615	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.730
DDX41	ENSMAMP00000009238	ENSMAMP00000016606	ENSMAMP00000009238	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 8.	0.778
DDX41	ENSMAMP00000010651	ENSMAMP00000016606	ENSMAMP00000010651	DEAD-box helicase 41.	Uncharacterized protein.	0.693
DDX41	ENSMAMP00000010653	ENSMAMP00000016606	ENSMAMP00000010653	DEAD-box helicase 41.	WD_REPEATS_REGION domain-containing protein.	0.693
DDX41	ENSMAMP00000020979	ENSMAMP00000016606	ENSMAMP00000020979	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 34.	0.778
DDX41	ENSMAMP00000025003	ENSMAMP00000016606	ENSMAMP00000025003	DEAD-box helicase 41.	Mtr4 exosome RNA helicase.	0.774
DDX41	cdc40	ENSMAMP00000016606	ENSMAMP00000030984	DEAD-box helicase 41.	Cell division cycle 40 homolog (S. cerevisiae).	0.839
DDX41	cwc22	ENSMAMP00000016606	ENSMAMP00000028120	DEAD-box helicase 41.	CWC22 spliceosome associated protein homolog.	0.781
DDX41	cwc27	ENSMAMP00000016606	ENSMAMP00000006868	DEAD-box helicase 41.	CWC27 spliceosome associated cyclophilin.	0.475
DDX41	ddx23	ENSMAMP00000016606	ENSMAMP00000035961	DEAD-box helicase 41.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.655
DDX41	dhx35	ENSMAMP00000016606	ENSMAMP00000015622	DEAD-box helicase 41.	DEAH-box helicase 35.	0.773
DDX41	dhx38	ENSMAMP00000016606	ENSMAMP00000031989	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 38.	0.782
DDX41	pnn	ENSMAMP00000016606	ENSMAMP00000019254	DEAD-box helicase 41.	Pinin, desmosome associated protein.	0.412
DDX41	ppie	ENSMAMP00000016606	ENSMAMP00000014742	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.575
DDX41	ppil1	ENSMAMP00000016606	ENSMAMP00000035316	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.835
DDX41	ppil2	ENSMAMP00000016606	ENSMAMP00000023455	DEAD-box helicase 41.	Peptidylprolyl isomerase (cyclophilin)-like 2.	0.653
DDX41	ppwd1	ENSMAMP00000016606	ENSMAMP00000006809	DEAD-box helicase 41.	Peptidylprolyl isomerase domain and WD repeat containing 1.	0.889
DDX41	srrm1	ENSMAMP00000016606	ENSMAMP00000015180	DEAD-box helicase 41.	Serine/arginine repetitive matrix 1.	0.839
ENSMAMP00000005952	ENSMAMP00000007615	ENSMAMP00000005952	ENSMAMP00000007615	annotation not available	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.492
ENSMAMP00000005952	ENSMAMP00000009238	ENSMAMP00000005952	ENSMAMP00000009238	annotation not available	DEAH (Asp-Glu-Ala-His) box polypeptide 8.	0.582