Your Input: | |
| | ENSMAMP00000031241 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (737 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (644 aa) |
| | helb | Helicase (DNA) B. (1066 aa) |
| | ENSMAMP00000034838 | SET domain and mariner transposase fusion gene. (302 aa) |
| | pms2 | PMS1 homolog 2, mismatch repair system component. (879 aa) |
| | ENSMAMP00000010610 | Nei-like DNA glycosylase 1. (455 aa) |
| | ENSMAMP00000010763 | Snf2-related CREBBP activator protein. (2956 aa) |
| | gen1 | Uncharacterized protein. (908 aa) |
| | LOC113140166 | Uncharacterized protein. (300 aa) |
| | LOC113140205 | Uncharacterized protein. (302 aa) |
| | ENSMAMP00000011343 | Uncharacterized protein. (303 aa) |
| | ENSMAMP00000011396 | Uncharacterized protein. (257 aa) |
| | ENSMAMP00000011414 | Exonuclease 1. (740 aa) |
| | PLD4 | Phospholipase D family member 4. (483 aa) |
| | LOC113145564 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (825 aa) |
| | ENSMAMP00000012077 | Uncharacterized protein. (1582 aa) |
| | ENSMAMP00000012087 | DNA (cytosine-5-)-methyltransferase beta, duplicate b.3; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (605 aa) |
| | top2a | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1574 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | lig4 | DNA ligase. (915 aa) |
| | ENSMAMP00000012848 | BLM RecQ like helicase. (1366 aa) |
| | ENSMAMP00000013291 | DNA ligase. (987 aa) |
| | atrx | ATRX chromatin remodeler. (2018 aa) |
| | chd2 | Chromodomain helicase DNA binding protein 2. (1815 aa) |
| | smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1627 aa) |
| | ENSMAMP00000014326 | Uncharacterized protein. (139 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (568 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (627 aa) |
| | hells | Helicase, lymphoid specific. (852 aa) |
| | ENSMAMP00000015134 | Basic, immunoglobulin-like variable motif containing. (481 aa) |
| | ENSMAMP00000015171 | Deoxyribonuclease; Belongs to the DNase I family. (294 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (541 aa) |
| | LOC113146214 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (765 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa) |
| | ddx11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (888 aa) |
| | pms1 | PMS1 homolog 1, mismatch repair system component. (911 aa) |
| | dnase2 | Deoxyribonuclease II, lysosomal. (377 aa) |
| | dclre1b | DNA cross-link repair 1B. (618 aa) |
| | rad51c | RAD51 paralog C. (363 aa) |
| | chd7 | Chromodomain helicase DNA binding protein 7. (3304 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (276 aa) |
| | ENSMAMP00000018099 | Autoimmune regulator. (433 aa) |
| | ENSMAMP00000018103 | Uncharacterized protein. (1670 aa) |
| | polk | Polymerase (DNA directed) kappa. (885 aa) |
| | ENSMAMP00000018289 | RAD54 homolog B. (881 aa) |
| | helq | Helicase, POLQ like. (1020 aa) |
| | dnmt1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1506 aa) |
| | dntt | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (498 aa) |
| | ENSMAMP00000018806 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (170 aa) |
| | ENSMAMP00000018813 | Uncharacterized protein. (113 aa) |
| | ENSMAMP00000018946 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated. (1792 aa) |
| | ENSMAMP00000019120 | 8-oxoguanine DNA glycosylase. (385 aa) |
| | chd1l | Chromodomain helicase DNA binding protein 1-like. (1015 aa) |
| | LOC113145588 | Deoxyribonuclease; Belongs to the DNase I family. (316 aa) |
| | chd6 | Chromodomain helicase DNA binding protein 6. (3572 aa) |
| | dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa) |
| | ENSMAMP00000019621 | Uncharacterized protein. (151 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | tdp2 | Tyrosyl-DNA phosphodiesterase 2b. (360 aa) |
| | ENSMAMP00000020458 | Uncharacterized protein. (189 aa) |
| | ENSMAMP00000020538 | INO80 complex ATPase subunit. (1004 aa) |
| | polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa) |
| | LOC113133528 | Thymine DNA glycosylase, tandem duplicate 1. (453 aa) |
| | LOC113132997 | Thymine DNA glycosylase, tandem duplicate 2. (398 aa) |
| | alkbh3 | AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase. (309 aa) |
| | ENSMAMP00000034629 | Uncharacterized protein. (139 aa) |
| | smarca5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1039 aa) |
| | smc3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1175 aa) |
| | ENSMAMP00000021691 | WRN helicase interacting protein 1. (621 aa) |
| | ENSMAMP00000021732 | Replication factor C (activator 1) 3. (423 aa) |
| | ENSMAMP00000022162 | DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (345 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa) |
| | ENSMAMP00000022264 | RAD1 homolog (S. pombe). (332 aa) |
| | msh3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1123 aa) |
| | LOC113145575 | Uncharacterized protein. (1565 aa) |
| | LOC113146216 | Deoxyribonuclease I-like 1. (322 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (704 aa) |
| | ENSMAMP00000023029 | Uncharacterized protein. (652 aa) |
| | haus3 | HAUS augmin-like complex, subunit 3. (654 aa) |
| | recql4 | RecQ helicase-like 4. (1548 aa) |
| | ENSMAMP00000023139 | Polymerase (DNA directed) nu. (724 aa) |
| | LOC113141958 | Cryptochrome circadian regulator 1a. (624 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (878 aa) |
| | ung | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (300 aa) |
| | ENSMAMP00000023657 | AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase. (242 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1316 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (527 aa) |
| | polq | Polymerase (DNA directed), theta. (2783 aa) |
| | smarcad1 | Uncharacterized protein. (1046 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | lig3 | DNA ligase. (1011 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa) |
| | ENSMAMP00000002154 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (350 aa) |
| | LOC113142649 | Remodeling and spacing factor 1b, tandem duplicate 1. (1725 aa) |
| | knl1 | Knl1_RWD_C domain-containing protein. (1933 aa) |
| | pold1 | DNA polymerase. (1119 aa) |
| | ENSMAMP00000002501 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1529 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | LOC113125640 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (998 aa) |
| | hltf | Helicase-like transcription factor. (967 aa) |
| | ENSMAMP00000003022 | Uncharacterized protein. (510 aa) |
| | ENSMAMP00000003219 | Uncharacterized protein. (1855 aa) |
| | LOC113121339 | Cryptochrome DASH. (532 aa) |
| | cry1 | Cryptochrome circadian regulator 1b. (570 aa) |
| | ENSMAMP00000003508 | Zgc:66475. (596 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | smarcal1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (879 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (723 aa) |
| | ENSMAMP00000000871 | Chromodomain helicase DNA binding protein 3. (1643 aa) |
| | LOC113145375 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1457 aa) |
| | fbh1 | F-box DNA helicase 1. (1089 aa) |
| | LOC113137443 | DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (842 aa) |
| | LOC113127486 | DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1030 aa) |
| | ddx1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa) |
| | ENSMAMP00000023876 | AlkB homolog 1, histone H2A dioxygenase. (353 aa) |
| | LOC113140449 | Deoxyribonuclease; Belongs to the DNase I family. (284 aa) |
| | pld3 | Phospholipase D family, member 3. (483 aa) |
| | ENSMAMP00000024367 | Chromodomain helicase DNA binding protein 8. (2554 aa) |
| | hmga2 | Uncharacterized protein. (120 aa) |
| | ercc2 | Excision repair cross-complementation group 2. (760 aa) |
| | ENSMAMP00000025018 | REV1 DNA directed polymerase. (1432 aa) |
| | dicer1 | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1908 aa) |
| | pgbd5 | PiggyBac transposable element derived 5. (533 aa) |
| | neil3 | Nei-like DNA glycosylase 3. (582 aa) |
| | ENSMAMP00000025964 | DNA helicase; Belongs to the MCM family. (825 aa) |
| | LOC113132594 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (565 aa) |
| | ENSMAMP00000026470 | Primase and polymerase (DNA-directed). (529 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (636 aa) |
| | LOC113123492 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (256 aa) |
| | RSF1 | PHD-type domain-containing protein. (1448 aa) |
| | LOC113133102 | Bromo domain-containing protein. (1637 aa) |
| | aptx | Aprataxin. (333 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa) |
| | ENSMAMP00000027426 | RECA_2 domain-containing protein. (291 aa) |
| | APLF | Aprataxin and PNKP like factor. (466 aa) |
| | ENSMAMP00000027658 | Excision repair cross-complementation group 6-like. (1292 aa) |
| | shprh | SNF2 histone linker PHD RING helicase. (1659 aa) |
| | LOC113126815 | Structural maintenance of chromosomes 6. (1085 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (644 aa) |
| | ankle1 | Uncharacterized protein. (1189 aa) |
| | chd4 | Uncharacterized protein. (1982 aa) |
| | alkbh4 | AlkB homolog 4, lysine demthylase. (275 aa) |
| | LOC113128267 | Uncharacterized protein. (1671 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (999 aa) |
| | LOC113144313 | Phospholipase D family, member 7. (880 aa) |
| | LOC113138368 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1600 aa) |
| | ercc5 | Excision repair cross-complementation group 5. (1147 aa) |
| | mpg | N-methylpurine DNA glycosylase. (314 aa) |
| | ENSMAMP00000004864 | BRCA1 interacting protein C-terminal helicase 1. (1153 aa) |
| | LOC113135203 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | ENSMAMP00000005063 | X-ray repair complementing defective repair in Chinese hamster cells 6. (605 aa) |
| | ENSMAMP00000005576 | MutS homolog 4. (781 aa) |
| | fto | FTO alpha-ketoglutarate dependent dioxygenase. (644 aa) |
| | chd9 | Chromodomain helicase DNA binding protein 9. (2987 aa) |
| | smug1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (282 aa) |
| | ENSMAMP00000006051 | RING-type domain-containing protein. (63 aa) |
| | LOC113135213 | Si:ch211-141o9.10. (309 aa) |
| | ENSMAMP00000006136 | Zgc:110269. (348 aa) |
| | dhx9 | DEAH (Asp-Glu-Ala-His) box helicase 9. (1186 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | LOC113126843 | Chromodomain helicase DNA binding protein 4a. (1947 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (656 aa) |
| | mgme1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (338 aa) |
| | tatdn1 | TatD DNase domain containing 1. (316 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (3044 aa) |
| | ENSMAMP00000006331 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (336 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1443 aa) |
| | ercc3 | Excision repair cross-complementation group 3. (783 aa) |
| | ercc4 | Excision repair cross-complementation group 4. (900 aa) |
| | gtf2f2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (270 aa) |
| | ENSMAMP00000006956 | Helicase for meiosis 1. (882 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (1149 aa) |
| | twnk | Twinkle mtDNA helicase. (730 aa) |
| | ENSMAMP00000007342 | E1A binding protein p400. (2852 aa) |
| | polg | Polymerase (DNA directed), gamma. (1203 aa) |
| | ENSMAMP00000007807 | Methyltransferase like 4; Belongs to the MT-A70-like family. (334 aa) |
| | MPHOSPH9 | M-phase phosphoprotein 9. (1255 aa) |
| | ENSMAMP00000007985 | Dyskeratosis congenita 1, dyskerin. (447 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (496 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (624 aa) |
| | ENSMAMP00000008170 | Immunoglobulin mu DNA binding protein 2. (968 aa) |
| | ENDOV | Endonuclease V. (256 aa) |
| | mlh3 | MutL homolog 3 (E. coli). (1173 aa) |
| | poli | Polymerase (DNA directed) iota. (721 aa) |
| | ascc3 | Activating signal cointegrator 1 complex subunit 3. (2204 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (469 aa) |
| | tert | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1110 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (622 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (814 aa) |
| | ENSMAMP00000010511 | Uncharacterized protein. (2126 aa) |
| | apex1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (343 aa) |
| | ENSMAMP00000035113 | Si:dkey-57n24.6. (677 aa) |
| | ENSMAMP00000035212 | ATPase family AAA domain containing 5a. (1802 aa) |
| | LOC113130271 | THAP-type domain-containing protein. (259 aa) |
| | rad54l2 | RAD54 like 2. (1511 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | ENSMAMP00000035870 | Methyl-CpG binding domain protein 4. (175 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (382 aa) |
| | apex2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (581 aa) |
| | polh | Polymerase (DNA directed), eta. (734 aa) |
| | rexo2 | Small fragment nuclease. (276 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | endog | Endonuclease. (302 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1381 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa) |
| | rad54l | RAD54 like. (740 aa) |
| | n6amt1 | N-6 adenine-specific DNA methyltransferase 1. (257 aa) |
| | ENSMAMP00000033196 | Uncharacterized protein. (194 aa) |
| | dnase2b | Deoxyribonuclease II beta. (351 aa) |
| | ENSMAMP00000033281 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (785 aa) |
| | chd1 | Chromodomain helicase DNA binding protein 1. (1792 aa) |
| | pola1 | DNA polymerase. (1480 aa) |
| | ENSMAMP00000029662 | Uncharacterized protein. (1166 aa) |
| | rps3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (263 aa) |
| | ENSMAMP00000029947 | Replication factor C subunit 1. (1137 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1400 aa) |
| | supv3l1 | SUV3-like helicase. (788 aa) |
| | ENSMAMP00000030314 | Transcription termination factor, RNA polymerase II. (1100 aa) |
| | LOC113137480 | Si:dkey-119f1.1. (1090 aa) |
| | ercc6l2 | Excision repair cross-complementation group 6-like 2. (1604 aa) |
