(34 nodes) Guanine-nucleotide dissociation stimulator, CDC24, conserved site network (Mastacembelus armatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ect2	Epithelial cell transforming 2. (1035 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (842 aa)
	ABR	ABR activator of RhoGEF and GTPase. (1095 aa)
	prex1	Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1644 aa)
	ENSMAMP00000012952	Uncharacterized protein. (1195 aa)
	LOC113145526	Rho guanine nucleotide exchange factor (GEF) 3, like. (522 aa)
	ENSMAMP00000014109	Intersectin 1 (SH3 domain protein). (1688 aa)
	arhgef12	Rho guanine nucleotide exchange factor (GEF) 12a. (1439 aa)
	LOC113125669	T cell lymphoma invasion and metastasis 1b. (1567 aa)
	LOC113143157	T cell lymphoma invasion and metastasis 1a. (1680 aa)
	arhgef11	Rho guanine nucleotide exchange factor (GEF) 11. (1433 aa)
	ENSMAMP00000021120	Rho guanine nucleotide exchange factor (GEF) 3. (591 aa)
	NET1	Uncharacterized protein. (567 aa)
	prex2	Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2. (1613 aa)
	LOC113127067	Mcf.2 cell line derived transforming sequence-like a. (1160 aa)
	arhgef4	Uncharacterized protein. (2271 aa)
	ENSMAMP00000030773	MCF.2 cell line derived transforming sequence a. (1077 aa)
	ENSMAMP00000011437	BCR activator of RhoGEF and GTPase. (799 aa)
	net1	Neuroepithelial cell transforming 1. (610 aa)
	RASGRF1	Ras protein specific guanine nucleotide releasing factor 1. (1200 aa)
	LOC113142823	Uncharacterized protein. (1447 aa)
	ENSMAMP00000005383	T cell lymphoma invasion and metastasis 2b. (459 aa)
	LOC113124270	Vav 2 guanine nucleotide exchange factor. (850 aa)
	arhgef1	Rho guanine nucleotide exchange factor (GEF) 1b. (1058 aa)
	vav3	Vav 3 guanine nucleotide exchange factor b. (836 aa)
	LOC113129074	MCF.2 cell line derived transforming sequence-like 2. (1042 aa)
	PLEKHG1	Pleckstrin homology and RhoGEF domain containing G1. (1599 aa)
	dnmbp	Dynamin binding protein. (1698 aa)
	ENSMAMP00000023613	Intersectin 2a. (1527 aa)
	arhgef38	Rho guanine nucleotide exchange factor (GEF) 38. (808 aa)
	ENSMAMP00000030403	Intersectin 2b. (1594 aa)
	bcr	Si:dkey-91m11.5. (1297 aa)
	ENSMAMP00000025259	Mcf.2 cell line derived transforming sequence-like b. (1128 aa)
	ENSMAMP00000025120	Rho guanine nucleotide exchange factor (GEF) 7a. (799 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMAMP00000005383	ENSMAMP00000014109	ENSMAMP00000005383	ENSMAMP00000014109	T cell lymphoma invasion and metastasis 2b.	Intersectin 1 (SH3 domain protein).	0.656
ENSMAMP00000005383	ENSMAMP00000023613	ENSMAMP00000005383	ENSMAMP00000023613	T cell lymphoma invasion and metastasis 2b.	Intersectin 2a.	0.659
ENSMAMP00000005383	ENSMAMP00000030403	ENSMAMP00000005383	ENSMAMP00000030403	T cell lymphoma invasion and metastasis 2b.	Intersectin 2b.	0.659
ENSMAMP00000005383	LOC113124270	ENSMAMP00000005383	ENSMAMP00000005457	T cell lymphoma invasion and metastasis 2b.	Vav 2 guanine nucleotide exchange factor.	0.619
ENSMAMP00000005383	LOC113142823	ENSMAMP00000005383	ENSMAMP00000001680	T cell lymphoma invasion and metastasis 2b.	Uncharacterized protein.	0.469
ENSMAMP00000005383	VAV1	ENSMAMP00000005383	ENSMAMP00000011076	T cell lymphoma invasion and metastasis 2b.	Vav guanine nucleotide exchange factor 1.	0.619
ENSMAMP00000005383	arhgef1	ENSMAMP00000005383	ENSMAMP00000007491	T cell lymphoma invasion and metastasis 2b.	Rho guanine nucleotide exchange factor (GEF) 1b.	0.459
ENSMAMP00000005383	arhgef11	ENSMAMP00000005383	ENSMAMP00000019991	T cell lymphoma invasion and metastasis 2b.	Rho guanine nucleotide exchange factor (GEF) 11.	0.459
ENSMAMP00000005383	arhgef12	ENSMAMP00000005383	ENSMAMP00000014610	T cell lymphoma invasion and metastasis 2b.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.469
ENSMAMP00000005383	vav3	ENSMAMP00000005383	ENSMAMP00000008445	T cell lymphoma invasion and metastasis 2b.	Vav 3 guanine nucleotide exchange factor b.	0.619
ENSMAMP00000012952	ENSMAMP00000014109	ENSMAMP00000012952	ENSMAMP00000014109	Uncharacterized protein.	Intersectin 1 (SH3 domain protein).	0.477
ENSMAMP00000012952	ENSMAMP00000023613	ENSMAMP00000012952	ENSMAMP00000023613	Uncharacterized protein.	Intersectin 2a.	0.510
ENSMAMP00000012952	ENSMAMP00000030403	ENSMAMP00000012952	ENSMAMP00000030403	Uncharacterized protein.	Intersectin 2b.	0.510
ENSMAMP00000012952	LOC113124270	ENSMAMP00000012952	ENSMAMP00000005457	Uncharacterized protein.	Vav 2 guanine nucleotide exchange factor.	0.476
ENSMAMP00000012952	VAV1	ENSMAMP00000012952	ENSMAMP00000011076	Uncharacterized protein.	Vav guanine nucleotide exchange factor 1.	0.476
ENSMAMP00000012952	vav3	ENSMAMP00000012952	ENSMAMP00000008445	Uncharacterized protein.	Vav 3 guanine nucleotide exchange factor b.	0.476
ENSMAMP00000014109	ENSMAMP00000005383	ENSMAMP00000014109	ENSMAMP00000005383	Intersectin 1 (SH3 domain protein).	T cell lymphoma invasion and metastasis 2b.	0.656
ENSMAMP00000014109	ENSMAMP00000012952	ENSMAMP00000014109	ENSMAMP00000012952	Intersectin 1 (SH3 domain protein).	Uncharacterized protein.	0.477
ENSMAMP00000014109	ENSMAMP00000023613	ENSMAMP00000014109	ENSMAMP00000023613	Intersectin 1 (SH3 domain protein).	Intersectin 2a.	0.985
ENSMAMP00000014109	ENSMAMP00000025120	ENSMAMP00000014109	ENSMAMP00000025120	Intersectin 1 (SH3 domain protein).	Rho guanine nucleotide exchange factor (GEF) 7a.	0.666