STRINGSTRING
RFC2 RFC2 ENSMAMP00000021732 ENSMAMP00000021732 terf2ip terf2ip pcna pcna LOC113121578 LOC113121578 prim2 prim2 ENSMAMP00000024977 ENSMAMP00000024977 RCBTB1 RCBTB1 rpa1 rpa1 RPA1 RPA1 ENSMAMP00000029947 ENSMAMP00000029947 DNA2 DNA2 LOC113146398 LOC113146398 LOC113127185 LOC113127185 fen1 fen1 ENSMAMP00000033957 ENSMAMP00000033957 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000018114 ENSMAMP00000018114 chtf8 chtf8 rcbtb2 rcbtb2 ENSMAMP00000016915 ENSMAMP00000016915 ENSMAMP00000016811 ENSMAMP00000016811 ENSMAMP00000016724 ENSMAMP00000016724 pold3 pold3 ENSMAMP00000013291 ENSMAMP00000013291 chtf18 chtf18 ENSMAMP00000012848 ENSMAMP00000012848 pold2 pold2 rpa2 rpa2 rfc4 rfc4 rfc5 rfc5 ENSMAMP00000006478 ENSMAMP00000006478 ENSMAMP00000006136 ENSMAMP00000006136 pold4 pold4 pold1 pold1 rpa3 rpa3 pola2 pola2 dscc1 dscc1 prim1 prim1 pola1 pola1 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC2Replication factor C (activator 1) 2. (359 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
terf2ipUncharacterized protein. (755 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC113121578TINF2_N domain-containing protein. (585 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (540 aa)
ENSMAMP00000024977TEN1 subunit of CST complex. (144 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029947Replication factor C subunit 1. (1137 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
LOC113146398HTH myb-type domain-containing protein. (608 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
ENSMAMP00000033957Protection of telomeres 1 homolog. (805 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000018114Uncharacterized protein. (493 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (135 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSMAMP00000016915Uncharacterized protein. (1070 aa)
ENSMAMP00000016811Uncharacterized protein. (1097 aa)
ENSMAMP00000016724Uncharacterized protein. (1090 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
ENSMAMP00000013291DNA ligase. (987 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (947 aa)
ENSMAMP00000012848BLM RecQ like helicase. (1366 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
rpa2Replication protein A2. (272 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSMAMP00000006478STN1 subunit of CST complex. (338 aa)
ENSMAMP00000006136Zgc:110269. (348 aa)
pold4Si:dkey-28b4.7. (108 aa)
pold1DNA polymerase. (1119 aa)
rpa3Replication protein A3. (122 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
dscc1DNA replication and sister chromatid cohesion 1. (390 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
pola1DNA polymerase. (1480 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.