100 items (Mastacembelus armatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (153 aa)
	ENSMAMP00000000395	Ribosomal protein S6 kinase. (808 aa)
	ENSMAMP00000001994	Protein phosphatase 4, regulatory subunit 4. (738 aa)
	LOC113140692	Zgc:55558. (223 aa)
	ENSMAMP00000002543	Mitogen-activated protein kinase. (358 aa)
	LOC113143160	Uncharacterized protein. (318 aa)
	LOC113141255	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
	LOC113134226	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC113128962	SHC (Src homology 2 domain containing) transforming protein 2. (732 aa)
	chd4	Uncharacterized protein. (1982 aa)
	LOC113128353	BHLH domain-containing protein. (450 aa)
	fnbp4	Formin binding protein 4. (936 aa)
	LOC113131245	Kinase D-interacting substrate 220b. (1745 aa)
	LOC113130928	Activating transcription factor 1. (311 aa)
	ENSMAMP00000004182	BHLH domain-containing protein. (119 aa)
	ENSMAMP00000005696	NTPase, KAP family P-loop domain containing 1. (693 aa)
	ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (983 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	ENSMAMP00000006672	Achaete-scute family bHLH transcription factor 1b. (181 aa)
	LOC113122547	Inhibitor of DNA binding 4. (137 aa)
	LOC113130941	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (201 aa)
	LOC113125670	CRK proto-oncogene, adaptor protein. (315 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	dnal4	Dynein light chain. (106 aa)
	ENSMAMP00000008939	Uncharacterized protein. (186 aa)
	ENSMAMP00000008967	WRNPLPNID domain-containing protein. (251 aa)
	ENSMAMP00000008995	Uncharacterized protein. (215 aa)
	LOC113135136	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (221 aa)
	ENSMAMP00000009026	NGFI-A binding protein 2 (EGR1 binding protein 2). (476 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	JUND	BZIP domain-containing protein. (291 aa)
	ENSMAMP00000009178	JunD proto-oncogene, AP-1 transcription factor subunit. (309 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
	id3	Inhibitor of DNA binding 3. (117 aa)
	LOC113129095	Ribosomal protein S6 kinase. (760 aa)
	LOC113145149	Mitogen-activated protein kinase. (364 aa)
	ENSMAMP00000011487	Uncharacterized protein. (358 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
	LOC113127776	JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (511 aa)
	LOC113142815	Ribosomal protein S6 kinase. (784 aa)
	ENSMAMP00000012469	Serine/threonine-protein phosphatase. (286 aa)
	LOC113127314	Insulin receptor substrate 2a. (1046 aa)
	kidins220	ANK_REP_REGION domain-containing protein. (1721 aa)
	LOC113145539	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (288 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (879 aa)
	LOC113129823	Mitogen-activated protein kinase. (361 aa)
	ap2a2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (969 aa)
	LOC113134821	Mitogen-activated protein kinase kinase 2b. (395 aa)
	ENSMAMP00000014993	Early growth response 3. (410 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC113145054	Mitogen-activated protein kinase. (360 aa)
	LOC113121375	V-ral simian leukemia viral oncogene homolog Aa (ras related). (279 aa)
	LOC113136604	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	trib2	Tribbles pseudokinase 2. (345 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
	LOC113134608	cAMP responsive element modulator a. (321 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1155 aa)
	ENSMAMP00000018204	ETS transcription factor ELK1. (775 aa)
	ENSMAMP00000018266	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC113126498	Tribbles pseudokinase 1. (362 aa)
	mapk15	Mitogen-activated protein kinase; Belongs to the VPS28 family. (784 aa)
	LOC113129927	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	SHC3	SHC adaptor protein 3. (575 aa)
	LOC113123341	V-ral simian leukemia viral oncogene homolog Ba (ras related). (222 aa)
	irs2	Insulin receptor substrate 2b. (1180 aa)
	LOC113128249	SH3 domain containing GRB2 like 2a, endophilin A1. (346 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	ENSMAMP00000024185	Achaete-scute family bHLH transcription factor 1a. (181 aa)
	srf	Serum response factor b. (601 aa)
	SGK1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
	ralgds	Ral guanine nucleotide dissociation stimulator. (849 aa)
	LOC113140875	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
	SRF	Serum response factor. (519 aa)
	ENSMAMP00000026174	Uncharacterized protein. (118 aa)
	LOC113124566	Rap guanine nucleotide exchange factor (GEF) 1b. (1185 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	LOC113143599	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (434 aa)
	LOC113126843	Chromodomain helicase DNA binding protein 4a. (1947 aa)
	LOC113123737	Uncharacterized protein. (330 aa)
	rapgef1	Uncharacterized protein. (912 aa)
	LOC113129226	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	LOC113142637	AP complex subunit beta. (953 aa)
	ENSMAMP00000030159	Non-specific serine/threonine protein kinase. (712 aa)
	LOC113130637	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (402 aa)
	egr2	Early growth response 2b. (448 aa)
	LOC113137908	VRK serine/threonine kinase 3. (586 aa)
	fosl1	FOS-like antigen 1a. (345 aa)
	CREB1	cAMP responsive element binding protein 1. (318 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (571 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	ENSMAMP00000033499	NGFI-A binding protein 1a (EGR1 binding protein 1). (501 aa)
	LOC113127156	Uncharacterized protein. (215 aa)
	ENSMAMP00000034017	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1188 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (419 aa)
	LOC113145821	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2M1	ENSMAMP00000002543	ENSMAMP00000009893	ENSMAMP00000002543	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.490
AP2M1	ENSMAMP00000005696	ENSMAMP00000009893	ENSMAMP00000005696	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	NTPase, KAP family P-loop domain containing 1.	0.461
AP2M1	ENSMAMP00000011487	ENSMAMP00000009893	ENSMAMP00000011487	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.623
AP2M1	LOC113127314	ENSMAMP00000009893	ENSMAMP00000012491	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Insulin receptor substrate 2a.	0.642
AP2M1	LOC113128249	ENSMAMP00000009893	ENSMAMP00000022921	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	SH3 domain containing GRB2 like 2a, endophilin A1.	0.623
AP2M1	LOC113129823	ENSMAMP00000009893	ENSMAMP00000013508	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.490
AP2M1	LOC113131245	ENSMAMP00000009893	ENSMAMP00000004044	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Kinase D-interacting substrate 220b.	0.461
AP2M1	LOC113141255	ENSMAMP00000009893	ENSMAMP00000003663	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.619
AP2M1	LOC113142637	ENSMAMP00000009893	ENSMAMP00000029407	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit beta.	0.989
AP2M1	LOC113145054	ENSMAMP00000009893	ENSMAMP00000016107	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.490
AP2M1	LOC113145149	ENSMAMP00000009893	ENSMAMP00000010709	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.490
AP2M1	ap2a1	ENSMAMP00000009893	ENSMAMP00000006197	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.997
AP2M1	ap2a2	ENSMAMP00000009893	ENSMAMP00000014320	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.993
AP2M1	ap2s1	ENSMAMP00000009893	ENSMAMP00000016235	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.994
AP2M1	clta	ENSMAMP00000009893	ENSMAMP00000023061	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.943
AP2M1	dnal4	ENSMAMP00000009893	ENSMAMP00000008380	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Dynein light chain.	0.634
AP2M1	irs2	ENSMAMP00000009893	ENSMAMP00000022369	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Insulin receptor substrate 2b.	0.642
AP2M1	kidins220	ENSMAMP00000009893	ENSMAMP00000012592	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	ANK_REP_REGION domain-containing protein.	0.461
AP2M1	mapk1	ENSMAMP00000009893	ENSMAMP00000023535	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.619
AP2M1	mapk15	ENSMAMP00000009893	ENSMAMP00000019492	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase; Belongs to the VPS28 family.	0.488