STRINGSTRING
psmd3 psmd3 prim1 prim1 E2F3 E2F3 LOC113130167 LOC113130167 ENSMAMP00000035562 ENSMAMP00000035562 mybl2 mybl2 psmc2 psmc2 cdkn1b cdkn1b ENSMAMP00000034412 ENSMAMP00000034412 LOC113133570 LOC113133570 ENSMAMP00000034198 ENSMAMP00000034198 wee1 wee1 pola1 pola1 ENSMAMP00000034017 ENSMAMP00000034017 LOC113124457 LOC113124457 skp2 skp2 rps27a rps27a orc4 orc4 ENSMAMP00000033281 ENSMAMP00000033281 psmb4 psmb4 LOC113131777 LOC113131777 ppp2ca ppp2ca ENSMAMP00000032272 ENSMAMP00000032272 LOC113141448 LOC113141448 LOC113137978 LOC113137978 lin9 lin9 psmb1 psmb1 ENSMAMP00000030097 ENSMAMP00000030097 RPA1 RPA1 ENSMAMP00000029439 ENSMAMP00000029439 ENSMAMP00000028424 ENSMAMP00000028424 mcm7 mcm7 LOC113136783 LOC113136783 PPP2R3B PPP2R3B ppp2cb ppp2cb rpa1 rpa1 psmd9 psmd9 LOC113121892 LOC113121892 psmd13 psmd13 psmd5 psmd5 pole3 pole3 LOC113141409 LOC113141409 LOC113132502 LOC113132502 ENSMAMP00000025964 ENSMAMP00000025964 e2f4 e2f4 orc2 orc2 cables1 cables1 MYBL2 MYBL2 LOC113126301 LOC113126301 dyrk1a dyrk1a LOC113126771 LOC113126771 ENSMAMP00000024456 ENSMAMP00000024456 tfdp1 tfdp1 psmd12 psmd12 LOC113128400 LOC113128400 lin37 lin37 ENSMAMP00000023615 ENSMAMP00000023615 LOC113132626 LOC113132626 mcm4 mcm4 prim2 prim2 orc1 orc1 ENSMAMP00000022360 ENSMAMP00000022360 pole pole ENSMAMP00000022053 ENSMAMP00000022053 prr5l prr5l cdc45 cdc45 CKS2 CKS2 ENSMAMP00000021285 ENSMAMP00000021285 ccna1 ccna1 LOC113126464 LOC113126464 LOC113126463 LOC113126463 psmb8 psmb8 psmc5 psmc5 LOC113138093 LOC113138093 psmd8 psmd8 rb1 rb1 gmnn gmnn LOC113132371 LOC113132371 orc5 orc5 psmd10 psmd10 LOC113136843 LOC113136843 LOC113141982 LOC113141982 ENSMAMP00000019835 ENSMAMP00000019835 ppp2r3c ppp2r3c psmf1 psmf1 ENSMAMP00000019698 ENSMAMP00000019698 mcm2 mcm2 cdk7 cdk7 dbf4 dbf4 psme2 psme2 LOC113124974 LOC113124974 LOC113133749 LOC113133749 LOC113144338 LOC113144338 fndc3a fndc3a psmd2 psmd2 ccnh ccnh LOC113133139 LOC113133139 LOC113140726 LOC113140726 ppp2r1b ppp2r1b ENSMAMP00000014226 ENSMAMP00000014226 cdk6 cdk6 psmc4 psmc4 LOC113124231 LOC113124231 cdt1 cdt1 psme1 psme1 cul1 cul1 ENSMAMP00000012512 ENSMAMP00000012512 ENSMAMP00000012469 ENSMAMP00000012469 mcm5 mcm5 LOC113138731 LOC113138731 ENSMAMP00000011911 ENSMAMP00000011911 psmc1 psmc1 LOC113137626 LOC113137626 ENSMAMP00000011559 ENSMAMP00000011559 orc3 orc3 akt1 akt1 ENSMAMP00000011048 ENSMAMP00000011048 kxd1 kxd1 rpa2 rpa2 CCNE2 CCNE2 mcm3 mcm3 ENSMAMP00000010199 ENSMAMP00000010199 psmd7 psmd7 e2f2 e2f2 psma3 psma3 ENSMAMP00000010066 ENSMAMP00000010066 LOC113145896 LOC113145896 ENSMAMP00000009615 ENSMAMP00000009615 LOC113135875 LOC113135875 uba52 uba52 LOC113141917 LOC113141917 LOC113134865 LOC113134865 LOC113142077 LOC113142077 pole2 pole2 meiob meiob ENSMAMP00000008995 ENSMAMP00000008995 ENSMAMP00000008967 ENSMAMP00000008967 ENSMAMP00000008939 ENSMAMP00000008939 psme3 psme3 SRC SRC cdk2 cdk2 LOC113145392 LOC113145392 ENSMAMP00000007755 ENSMAMP00000007755 psmb3 psmb3 psmd14 psmd14 lin54 lin54 ENSMAMP00000007077 ENSMAMP00000007077 LOC113125862 LOC113125862 cdk4 cdk4 psmb2 psmb2 cdkn2c cdkn2c pole4 pole4 LOC113129257 LOC113129257 LOC113124879 LOC113124879 cdkn2d cdkn2d LOC113142847 LOC113142847 fnbp4 fnbp4 LOC113129515 LOC113129515 LOC113137378 LOC113137378 mnat1 mnat1 ENSMAMP00000002281 ENSMAMP00000002281 ENSMAMP00000002267 ENSMAMP00000002267 ppp2r3a ppp2r3a ENSMAMP00000001994 ENSMAMP00000001994 fndc3b fndc3b psmc6 psmc6 psmd1 psmd1 mcm10 mcm10 LOC113128348 LOC113128348 mcm9 mcm9 CABLES2 CABLES2 psma2 psma2 rpa3 rpa3 pola2 pola2 ENSMAMP00000000758 ENSMAMP00000000758 ENSMAMP00000000619 ENSMAMP00000000619 ENSMAMP00000000617 ENSMAMP00000000617 LOC113122397 LOC113122397 CDC25B CDC25B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psmd3Proteasome 26S subunit, non-ATPase 3. (517 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
E2F3E2F transcription factor 3. (442 aa)
LOC113130167Cyclin-dependent kinase inhibitor 1A. (225 aa)
ENSMAMP00000035562Cyclin D3; Belongs to the cyclin family. (376 aa)
mybl2V-myb avian myeloblastosis viral oncogene homolog-like 2b. (637 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
ENSMAMP00000034412Uncharacterized protein. (295 aa)
LOC113133570Proteasome subunit alpha type. (261 aa)
ENSMAMP00000034198Proteasome endopeptidase complex. (273 aa)
wee1Wee1-like protein kinase. (620 aa)
pola1DNA polymerase. (1480 aa)
ENSMAMP00000034017RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1188 aa)
LOC113124457Proteasome subunit beta. (303 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (416 aa)
rps27aRibosomal protein S27a. (156 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
ENSMAMP00000033281Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (785 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (261 aa)
LOC113131777Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (499 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
ENSMAMP00000032272S-phase kinase-associated protein 1; Belongs to the SKP1 family. (220 aa)
LOC113141448Cyclin Dx; Belongs to the cyclin family. (320 aa)
LOC113137978E2F_TDP domain-containing protein. (347 aa)
lin9Lin-9 DREAM MuvB core complex component. (497 aa)
psmb1Proteasome subunit beta. (237 aa)
ENSMAMP00000030097Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (448 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029439Proteasome 26S subunit, non-ATPase 6. (402 aa)
ENSMAMP00000028424Proteasome subunit beta. (275 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
LOC113136783Cyclin E2; Belongs to the cyclin family. (395 aa)
PPP2R3BProtein phosphatase 2 regulatory subunit B''beta. (581 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
LOC113121892Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa)
LOC113141409PCI domain-containing protein. (422 aa)
LOC113132502Cyclin D2, a; Belongs to the cyclin family. (297 aa)
ENSMAMP00000025964DNA helicase; Belongs to the MCM family. (825 aa)
e2f4E2F transcription factor 4. (391 aa)
orc2Origin recognition complex, subunit 2. (574 aa)
cables1Cdk5 and Abl enzyme substrate 1. (532 aa)
MYBL2Uncharacterized protein. (889 aa)
LOC113126301Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
dyrk1aDual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b. (765 aa)
LOC113126771Proteasome 26S subunit, non-ATPase 4a. (368 aa)
ENSMAMP00000024456Retinoblastoma binding protein 8-like. (615 aa)
tfdp1Transcription factor. (413 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
LOC113128400Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (127 aa)
lin37Lin-37 DREAM MuvB core complex component. (243 aa)
ENSMAMP00000023615Cyclin A2; Belongs to the cyclin family. (423 aa)
LOC113132626Retinoblastoma-like 2 (p130). (1079 aa)
mcm4DNA helicase; Belongs to the MCM family. (878 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (540 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (898 aa)
ENSMAMP00000022360Uncharacterized protein. (130 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
ENSMAMP00000022053Proteasome subunit beta. (271 aa)
prr5lUncharacterized protein. (387 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
ENSMAMP00000021285Proteasome subunit beta 9a. (160 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)
LOC113126464Proteasome subunit beta 12. (217 aa)
LOC113126463Proteasome subunit beta. (275 aa)
psmb8Proteasome subunit beta. (278 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
LOC113138093Proteasome subunit alpha type. (287 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (300 aa)
rb1Retinoblastoma 1. (912 aa)
gmnnGeminin DNA replication inhibitor. (226 aa)
LOC113132371Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (584 aa)
orc5Origin recognition complex, subunit 5. (444 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC113136843Proteasome 26S subunit, non-ATPase 4b. (372 aa)
LOC113141982Cyclin D2, b; Belongs to the cyclin family. (294 aa)
ENSMAMP00000019835Retinoblastoma-like 1 (p107). (1036 aa)
ppp2r3cProtein phosphatase 2, regulatory subunit B'', gamma. (457 aa)
psmf1Proteasome inhibitor subunit 1. (276 aa)
ENSMAMP00000019698Proteasome endopeptidase complex. (253 aa)
mcm2DNA helicase; Belongs to the MCM family. (890 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
dbf4DBF4 zinc finger. (628 aa)
psme2Proteasome activator subunit 2. (245 aa)
LOC113124974Tyrosine-protein kinase. (1122 aa)
LOC113133749Proteasome subunit alpha type. (246 aa)
LOC113144338Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
fndc3aFibronectin type III domain containing 3A. (1235 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
ccnhCyclin H; Belongs to the cyclin family. (326 aa)
LOC113133139Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (294 aa)
LOC113140726Proteasome subunit beta. (233 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
ENSMAMP00000014226Cyclin E1; Belongs to the cyclin family. (383 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
LOC113124231Tyrosine-protein kinase. (1141 aa)
cdt1Chromatin licensing and DNA replication factor 1. (661 aa)
psme1Proteasome activator subunit 1. (247 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
ENSMAMP00000012512Proteasome subunit alpha type. (242 aa)
ENSMAMP00000012469Serine/threonine-protein phosphatase. (286 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
LOC113138731Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (448 aa)
ENSMAMP00000011911E2F transcription factor 1. (387 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
LOC113137626Proteasome subunit alpha type. (246 aa)
ENSMAMP00000011559Tyrosine-protein kinase. (512 aa)
orc3Origin recognition complex, subunit 3. (722 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
ENSMAMP00000011048Uncharacterized protein. (139 aa)
kxd1KxDL motif containing 1. (184 aa)
rpa2Replication protein A2. (272 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (381 aa)
mcm3DNA helicase; Belongs to the MCM family. (814 aa)
ENSMAMP00000010199Tyrosine-protein kinase. (1114 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (328 aa)
e2f2Si:ch211-160f23.5. (448 aa)
psma3Proteasome subunit alpha type. (255 aa)
ENSMAMP00000010066Uncharacterized protein. (140 aa)
LOC113145896Cdk5 and Abl enzyme substrate 2b. (539 aa)
ENSMAMP00000009615Lin-52 DREAM MuvB core complex component. (116 aa)
LOC113135875Proteasome 26S subunit, non-ATPase 11b. (422 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC113141917Cyclin-dependent kinase inhibitor 1D. (191 aa)
LOC113134865Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC113142077Uncharacterized protein. (176 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
ENSMAMP00000008995Uncharacterized protein. (215 aa)
ENSMAMP00000008967WRNPLPNID domain-containing protein. (251 aa)
ENSMAMP00000008939Uncharacterized protein. (186 aa)
psme3Proteasome activator subunit 3. (256 aa)
SRCTyrosine-protein kinase. (544 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC113145392Tyrosine-protein kinase. (537 aa)
ENSMAMP00000007755Protein kinase domain-containing protein. (164 aa)
psmb3Proteasome subunit beta. (205 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
lin54Lin-54 DREAM MuvB core complex component. (803 aa)
ENSMAMP00000007077Cell division cycle 7 homolog (S. cerevisiae). (580 aa)
LOC113125862E2F_TDP domain-containing protein. (413 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)
psmb2Proteasome subunit beta. (199 aa)
cdkn2cCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (160 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa)
LOC113129257SCY domain-containing protein. (124 aa)
LOC113124879Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (445 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (226 aa)
LOC113142847Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
fnbp4Formin binding protein 4. (936 aa)
LOC113129515Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
LOC113137378Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ENSMAMP00000002281E2F transcription factor 5. (144 aa)
ENSMAMP00000002267E2F transcription factor 5. (149 aa)
ppp2r3aProtein phosphatase 2, regulatory subunit B'', alpha. (1372 aa)
ENSMAMP00000001994Protein phosphatase 4, regulatory subunit 4. (738 aa)
fndc3bFibronectin type III domain containing 3Ba. (1205 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (949 aa)
LOC113128348Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (585 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1316 aa)
CABLES2Cdk5 and Abl enzyme substrate 2a; Belongs to the cyclin family. (511 aa)
psma2Proteasome subunit alpha type. (234 aa)
rpa3Replication protein A3. (122 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
ENSMAMP00000000758Wee1-like protein kinase. (551 aa)
ENSMAMP00000000619Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (456 aa)
ENSMAMP00000000617PA28_beta domain-containing protein. (124 aa)
LOC113122397Cyclin D1; Belongs to the cyclin family. (292 aa)
CDC25BCell division cycle 25B. (575 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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