STRINGSTRING
ENSMAMP00000035212 ENSMAMP00000035212 rpa3 rpa3 pold1 pold1 ENSMAMP00000003022 ENSMAMP00000003022 pold4 pold4 pole4 pole4 ENSMAMP00000006136 ENSMAMP00000006136 rfc5 rfc5 meiob meiob pole2 pole2 rfc4 rfc4 rpa2 rpa2 pold2 pold2 ENSMAMP00000013291 ENSMAMP00000013291 pold3 pold3 rcbtb2 rcbtb2 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 RFC2 RFC2 polb polb ENSMAMP00000021732 ENSMAMP00000021732 pole pole pcna pcna RCBTB1 RCBTB1 apex2 apex2 pole3 pole3 rpa1 rpa1 RPA1 RPA1 ENSMAMP00000029947 ENSMAMP00000029947 LOC113127185 LOC113127185 fen1 fen1 apex1 apex1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAMP00000035212ATPase family AAA domain containing 5a. (1802 aa)
rpa3Replication protein A3. (122 aa)
pold1DNA polymerase. (1119 aa)
ENSMAMP00000003022Uncharacterized protein. (510 aa)
pold4Si:dkey-28b4.7. (108 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa)
ENSMAMP00000006136Zgc:110269. (348 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
rpa2Replication protein A2. (272 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
ENSMAMP00000013291DNA ligase. (987 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (581 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029947Replication factor C subunit 1. (1137 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (343 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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