53 items (Mastacembelus armatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMAMP00000013496	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (957 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1308 aa)
	LOC113136604	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	SHC4	SHC adaptor protein 4. (571 aa)
	ENSMAMP00000013439	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	ENSMAMP00000013233	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (61 aa)
	ENSMAMP00000013219	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (166 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (879 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	ENSMAMP00000012469	Serine/threonine-protein phosphatase. (286 aa)
	ENSMAMP00000011048	Uncharacterized protein. (139 aa)
	ENSMAMP00000010899	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	LOC113139269	PH domain-containing protein. (753 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1235 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (267 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC113134865	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ENSMAMP00000009055	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC113145392	Tyrosine-protein kinase. (537 aa)
	ENSMAMP00000007757	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (519 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	spry2	Sprouty RTK signaling antagonist 2. (344 aa)
	LOC113142626	Uncharacterized protein. (867 aa)
	LOC113134226	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC113141255	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
	LOC113140692	Zgc:55558. (223 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1205 aa)
	LOC113144125	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (189 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (453 aa)
	gab1	GRB2-associated binding protein 1. (788 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (157 aa)
	LOC113128501	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
	ENSMAMP00000022901	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC113144967	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	ENSMAMP00000027811	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	ENSMAMP00000030862	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
	LOC113122538	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (571 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC113130798	Fibroblast growth factor receptor substrate 3. (619 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSMAMP00000009055	ENSMAMP00000013132	ENSMAMP00000009055	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.538
CSDE1	ENSMAMP00000010899	ENSMAMP00000013132	ENSMAMP00000010899	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
CSDE1	ENSMAMP00000011048	ENSMAMP00000013132	ENSMAMP00000011048	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.713
CSDE1	ENSMAMP00000012469	ENSMAMP00000013132	ENSMAMP00000012469	Cold shock domain containing E1, RNA-binding.	Serine/threonine-protein phosphatase.	0.569
CSDE1	ENSMAMP00000013219	ENSMAMP00000013132	ENSMAMP00000013219	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.444
CSDE1	ENSMAMP00000013233	ENSMAMP00000013132	ENSMAMP00000013233	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...]	0.444
CSDE1	ENSMAMP00000013439	ENSMAMP00000013132	ENSMAMP00000013439	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.525
CSDE1	ENSMAMP00000013496	ENSMAMP00000013132	ENSMAMP00000013496	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.430
CSDE1	ENSMAMP00000022901	ENSMAMP00000013132	ENSMAMP00000022901	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.538
CSDE1	ENSMAMP00000027811	ENSMAMP00000013132	ENSMAMP00000027811	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.509
CSDE1	ENSMAMP00000030862	ENSMAMP00000013132	ENSMAMP00000030862	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.508
CSDE1	LOC113122538	ENSMAMP00000013132	ENSMAMP00000030867	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
CSDE1	LOC113128501	ENSMAMP00000013132	ENSMAMP00000022778	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.430
CSDE1	LOC113130798	ENSMAMP00000013132	ENSMAMP00000035311	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 3.	0.532
CSDE1	LOC113134226	ENSMAMP00000013132	ENSMAMP00000003817	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.715
CSDE1	LOC113134865	ENSMAMP00000013132	ENSMAMP00000009351	Cold shock domain containing E1, RNA-binding.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.591
CSDE1	LOC113136604	ENSMAMP00000013132	ENSMAMP00000017069	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.715
CSDE1	LOC113139269	ENSMAMP00000013132	ENSMAMP00000009550	Cold shock domain containing E1, RNA-binding.	PH domain-containing protein.	0.473
CSDE1	LOC113141255	ENSMAMP00000013132	ENSMAMP00000003663	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.689
CSDE1	LOC113144125	ENSMAMP00000013132	ENSMAMP00000001514	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467