STRINGSTRING
rpa1 rpa1 rad17 rad17 cdca7l cdca7l ENSMAMP00000012848 ENSMAMP00000012848 ENSMAMP00000011414 ENSMAMP00000011414 rpa2 rpa2 rad52 rad52 rfc4 rfc4 ankrd12 ankrd12 top3a top3a meiob meiob cdca7 cdca7 rfc5 rfc5 tdrd3 tdrd3 ENSMAMP00000005495 ENSMAMP00000005495 rmi2 rmi2 ENSMAMP00000002715 ENSMAMP00000002715 rad9a rad9a rmi1 rmi1 ankrd11 ankrd11 atrip atrip rad51 rad51 rpa3 rpa3 exd2 exd2 RCBTB1 RCBTB1 kat5 kat5 brca1 brca1 recql4 recql4 ENSMAMP00000022264 ENSMAMP00000022264 rhno1 rhno1 ENSMAMP00000021732 ENSMAMP00000021732 nbn nbn RFC2 RFC2 ENSMAMP00000019064 ENSMAMP00000019064 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000018993 ENSMAMP00000018993 LOC113127185 LOC113127185 hus1 hus1 rad50 rad50 DNA2 DNA2 LOC113124974 LOC113124974 rcbtb2 rcbtb2 slf1 slf1 RPA1 RPA1 ENSMAMP00000015820 ENSMAMP00000015820 mre11 mre11 ENSMAMP00000026820 ENSMAMP00000026820
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
rad17RAD17 checkpoint clamp loader component. (636 aa)
cdca7lCell division cycle associated 7b. (409 aa)
ENSMAMP00000012848BLM RecQ like helicase. (1366 aa)
ENSMAMP00000011414Exonuclease 1. (740 aa)
rpa2Replication protein A2. (272 aa)
rad52RAD52 homolog, DNA repair protein. (437 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
ankrd12Ankyrin repeat domain 12. (1938 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
cdca7Cell division cycle associated 7a. (400 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
tdrd3Tudor domain containing 3. (785 aa)
ENSMAMP00000005495Non-specific serine/threonine protein kinase. (3067 aa)
rmi2RecQ mediated genome instability 2. (138 aa)
ENSMAMP00000002715ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa)
ankrd11Ankyrin repeat domain 11. (2837 aa)
atripUncharacterized protein. (812 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
rpa3Replication protein A3. (122 aa)
exd2Exonuclease 3'-5' domain containing 2. (644 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa)
brca1Uncharacterized protein. (1442 aa)
recql4RecQ helicase-like 4. (1548 aa)
ENSMAMP00000022264RAD1 homolog (S. pombe). (332 aa)
rhno1Si:ch73-352p4.5. (294 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
nbnNibrin. (845 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (315 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
LOC113124974Tyrosine-protein kinase. (1122 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
slf1SMC5-SMC6 complex localization factor 1. (879 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000015820DNA topoisomerase II binding protein 1. (1389 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
ENSMAMP00000026820SAE2 domain-containing protein. (90 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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