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| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa) |
| | LOC113145321 | Uncharacterized protein. (411 aa) |
| | parp3 | Poly [ADP-ribose] polymerase. (531 aa) |
| | sumo2 | Small ubiquitin-related modifier. (95 aa) |
| | ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (422 aa) |
| | ENSMAMP00000033998 | BRCA1/BRCA2-containing complex, subunit 3. (264 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | ENSMAMP00000033312 | RAP80_UIM domain-containing protein. (151 aa) |
| | ENSMAMP00000033310 | Uncharacterized protein. (533 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa) |
| | LOC113127185 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (315 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | polh | Polymerase (DNA directed), eta. (734 aa) |
| | parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1010 aa) |
| | ENSMAMP00000030253 | Histone H2B; Belongs to the histone H2B family. (153 aa) |
| | ENSMAMP00000030060 | Essential meiotic structure-specific endonuclease 1. (511 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1400 aa) |
| | ENSMAMP00000029947 | Replication factor C subunit 1. (1137 aa) |
| | ENSMAMP00000029931 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | ENSMAMP00000029925 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (497 aa) |
| | rnf169 | Ring finger protein 169. (589 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (490 aa) |
| | ENSMAMP00000027426 | RECA_2 domain-containing protein. (291 aa) |
| | ENSMAMP00000026820 | SAE2 domain-containing protein. (90 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (636 aa) |
| | ENSMAMP00000025642 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (305 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa) |
| | ENSMAMP00000023704 | Histone H2B; Belongs to the histone H2B family. (132 aa) |
| | brca1 | Uncharacterized protein. (1442 aa) |
| | ENSMAMP00000023615 | Cyclin A2; Belongs to the cyclin family. (423 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | recql4 | RecQ helicase-like 4. (1548 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (937 aa) |
| | ENSMAMP00000022465 | Reverse transcriptase domain-containing protein. (357 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | ENSMAMP00000022264 | RAD1 homolog (S. pombe). (332 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa) |
| | ENSMAMP00000022246 | Reverse transcriptase domain-containing protein. (271 aa) |
| | rhno1 | Si:ch73-352p4.5. (294 aa) |
| | ENSMAMP00000021732 | Replication factor C (activator 1) 3. (423 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (402 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1831 aa) |
| | rad51ap1 | RAD51 associated protein 1. (322 aa) |
| | ENSMAMP00000019646 | Reverse transcriptase domain-containing protein. (271 aa) |
| | nbn | Nibrin. (845 aa) |
| | RFC2 | Replication factor C (activator 1) 2. (359 aa) |
| | ENSMAMP00000019064 | ATPase_AAA_core domain-containing protein. (146 aa) |
| | ENSMAMP00000019030 | ATPase_AAA_core domain-containing protein. (97 aa) |
| | ENSMAMP00000018993 | ATPase_AAA_core domain-containing protein. (157 aa) |
| | LOC113124974 | Tyrosine-protein kinase. (1122 aa) |
| | ENSMAMP00000018386 | Abraxas 1, BRCA1 A complex subunit. (336 aa) |
| | polk | Polymerase (DNA directed) kappa. (885 aa) |
| | ENSMAMP00000018168 | annotation not available (93 aa) |
| | rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | LOC113132336 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | rad51c | RAD51 paralog C. (363 aa) |
| | ENSMAMP00000016919 | Histone H2A; Belongs to the histone H2A family. (136 aa) |
| | sirt7 | Sirtuin 7. (406 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | ENSMAMP00000016271 | Reverse transcriptase domain-containing protein. (293 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa) |
| | ENSMAMP00000015820 | DNA topoisomerase II binding protein 1. (1389 aa) |
| | ENSMAMP00000015732 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | brca2 | BRCA2 DNA repair associated. (2876 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa) |
| | cdca7l | Cell division cycle associated 7b. (409 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (627 aa) |
| | LOC113142143 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | ENSMAMP00000014297 | Reverse transcriptase domain-containing protein. (699 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | sirt6 | Sirtuin 6. (348 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (630 aa) |
| | ENSMAMP00000012848 | BLM RecQ like helicase. (1366 aa) |
| | parp2 | Poly [ADP-ribose] polymerase. (649 aa) |
| | ENSMAMP00000011414 | Exonuclease 1. (740 aa) |
| | ENSMAMP00000011048 | Uncharacterized protein. (139 aa) |
| | gen1 | Uncharacterized protein. (908 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa) |
| | kxd1 | KxDL motif containing 1. (184 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1404 aa) |
| | rpa2 | Replication protein A2. (272 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (373 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (437 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (376 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1938 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | LOC113134865 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (469 aa) |
| | ube2n | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | cdca7 | Cell division cycle associated 7a. (400 aa) |
| | LOC113140814 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ENSMAMP00000007755 | Protein kinase domain-containing protein. (164 aa) |
| | ENSMAMP00000007108 | Timeless circadian clock. (1221 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (534 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | LOC113129987 | Ubiquitin-like domain-containing protein. (99 aa) |
| | ENSMAMP00000006136 | Zgc:110269. (348 aa) |
| | tdrd3 | Tudor domain containing 3. (785 aa) |
| | mdc1 | Uncharacterized protein. (1884 aa) |
| | ENSMAMP00000005495 | Non-specific serine/threonine protein kinase. (3067 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa) |
| | pold4 | Si:dkey-28b4.7. (108 aa) |
| | ENSMAMP00000003996 | Uncharacterized protein; Belongs to the histone H2B family. (157 aa) |
| | rmi2 | RecQ mediated genome instability 2. (138 aa) |
| | LOC113125640 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa) |
| | ENSMAMP00000002715 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | LOC113123972 | Small ubiquitin-related modifier. (95 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2837 aa) |
| | atrip | Uncharacterized protein. (812 aa) |
| | pold1 | DNA polymerase. (1119 aa) |
| | LOC113142797 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC113128185 | Small ubiquitin-related modifier. (96 aa) |
| | ENSMAMP00000002197 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (156 aa) |
| | ENSMAMP00000002154 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (350 aa) |
| | ENSMAMP00000001831 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | ENSMAMP00000001732 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | ENSMAMP00000001719 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (148 aa) |
| | ENSMAMP00000001553 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | lig3 | DNA ligase. (1011 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | polq | Polymerase (DNA directed), theta. (2783 aa) |
| | LOC113128524 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (644 aa) |
| | ENSMAMP00000000117 | Nuclear receptor binding SET domain protein 2. (1285 aa) |
