STRINGSTRING
ENSMAMP00000000117 ENSMAMP00000000117 rpa3 rpa3 LOC113128524 LOC113128524 ENSMAMP00000001553 ENSMAMP00000001553 ENSMAMP00000001719 ENSMAMP00000001719 ENSMAMP00000001732 ENSMAMP00000001732 ENSMAMP00000001831 ENSMAMP00000001831 ENSMAMP00000002197 ENSMAMP00000002197 LOC113128185 LOC113128185 LOC113142797 LOC113142797 atrip atrip ankrd11 ankrd11 LOC113123972 LOC113123972 ppp4c ppp4c rmi1 rmi1 rad9a rad9a ENSMAMP00000002715 ENSMAMP00000002715 rmi2 rmi2 ENSMAMP00000005495 ENSMAMP00000005495 mdc1 mdc1 LOC113129987 LOC113129987 rfc5 rfc5 rnf8 rnf8 ENSMAMP00000007108 ENSMAMP00000007108 ENSMAMP00000007755 ENSMAMP00000007755 cdk2 cdk2 LOC113140814 LOC113140814 ube2n ube2n top3a top3a ankrd12 ankrd12 rfc4 rfc4 babam1 babam1 rpa2 rpa2 ENSMAMP00000011414 ENSMAMP00000011414 ENSMAMP00000012848 ENSMAMP00000012848 sirt6 sirt6 ube2i ube2i ENSMAMP00000014297 ENSMAMP00000014297 LOC113142143 LOC113142143 mre11 mre11 ENSMAMP00000015732 ENSMAMP00000015732 ENSMAMP00000015820 ENSMAMP00000015820 ENSMAMP00000016271 ENSMAMP00000016271 ENSMAMP00000016919 ENSMAMP00000016919 LOC113132336 LOC113132336 rcbtb2 rcbtb2 ENSMAMP00000018168 ENSMAMP00000018168 ENSMAMP00000018386 ENSMAMP00000018386 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 RFC2 RFC2 nbn nbn ENSMAMP00000019646 ENSMAMP00000019646 ccna1 ccna1 babam2 babam2 ENSMAMP00000021732 ENSMAMP00000021732 rhno1 rhno1 ENSMAMP00000022246 ENSMAMP00000022246 ENSMAMP00000022264 ENSMAMP00000022264 ENSMAMP00000022465 ENSMAMP00000022465 recql4 recql4 ube2v2 ube2v2 ENSMAMP00000023615 ENSMAMP00000023615 brca1 brca1 ENSMAMP00000023704 ENSMAMP00000023704 kat5 kat5 RCBTB1 RCBTB1 ENSMAMP00000025642 ENSMAMP00000025642 rad17 rad17 rpa1 rpa1 ENSMAMP00000026820 ENSMAMP00000026820 rnf169 rnf169 pias4 pias4 RPA1 RPA1 ENSMAMP00000029925 ENSMAMP00000029925 ENSMAMP00000029931 ENSMAMP00000029931 DNA2 DNA2 ENSMAMP00000030253 ENSMAMP00000030253 rad50 rad50 hus1 hus1 LOC113127185 LOC113127185 ENSMAMP00000033310 ENSMAMP00000033310 ENSMAMP00000033312 ENSMAMP00000033312 ENSMAMP00000033998 ENSMAMP00000033998 ppp4r2 ppp4r2 sumo2 sumo2 LOC113145321 LOC113145321
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAMP00000000117Nuclear receptor binding SET domain protein 2. (1285 aa)
rpa3Replication protein A3. (122 aa)
LOC113128524Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSMAMP00000001553Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSMAMP00000001719UBIQUITIN_CONJUGAT_2 domain-containing protein. (148 aa)
ENSMAMP00000001732Histone H2B; Belongs to the histone H2B family. (117 aa)
ENSMAMP00000001831Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
ENSMAMP00000002197Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (156 aa)
LOC113128185Small ubiquitin-related modifier. (96 aa)
LOC113142797Histone H2B; Belongs to the histone H2B family. (126 aa)
atripUncharacterized protein. (812 aa)
ankrd11Ankyrin repeat domain 11. (2837 aa)
LOC113123972Small ubiquitin-related modifier. (95 aa)
ppp4cSerine/threonine-protein phosphatase. (311 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
ENSMAMP00000002715ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa)
rmi2RecQ mediated genome instability 2. (138 aa)
ENSMAMP00000005495Non-specific serine/threonine protein kinase. (3067 aa)
mdc1Uncharacterized protein. (1884 aa)
LOC113129987Ubiquitin-like domain-containing protein. (99 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (534 aa)
ENSMAMP00000007108Timeless circadian clock. (1221 aa)
ENSMAMP00000007755Protein kinase domain-containing protein. (164 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC113140814UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ube2nUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa)
ankrd12Ankyrin repeat domain 12. (1938 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
babam1BRISC and BRCA1 A complex member 1. (373 aa)
rpa2Replication protein A2. (272 aa)
ENSMAMP00000011414Exonuclease 1. (740 aa)
ENSMAMP00000012848BLM RecQ like helicase. (1366 aa)
sirt6Sirtuin 6. (348 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ENSMAMP00000014297Reverse transcriptase domain-containing protein. (699 aa)
LOC113142143UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
ENSMAMP00000015732Histone H2B; Belongs to the histone H2B family. (118 aa)
ENSMAMP00000015820DNA topoisomerase II binding protein 1. (1389 aa)
ENSMAMP00000016271Reverse transcriptase domain-containing protein. (293 aa)
ENSMAMP00000016919Histone H2A; Belongs to the histone H2A family. (136 aa)
LOC113132336Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSMAMP00000018168annotation not available (93 aa)
ENSMAMP00000018386Abraxas 1, BRCA1 A complex subunit. (336 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
nbnNibrin. (845 aa)
ENSMAMP00000019646Reverse transcriptase domain-containing protein. (271 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
rhno1Si:ch73-352p4.5. (294 aa)
ENSMAMP00000022246Reverse transcriptase domain-containing protein. (271 aa)
ENSMAMP00000022264RAD1 homolog (S. pombe). (332 aa)
ENSMAMP00000022465Reverse transcriptase domain-containing protein. (357 aa)
recql4RecQ helicase-like 4. (1548 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
ENSMAMP00000023615Cyclin A2; Belongs to the cyclin family. (423 aa)
brca1Uncharacterized protein. (1442 aa)
ENSMAMP00000023704Histone H2B; Belongs to the histone H2B family. (132 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
ENSMAMP00000025642TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (305 aa)
rad17RAD17 checkpoint clamp loader component. (636 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ENSMAMP00000026820SAE2 domain-containing protein. (90 aa)
rnf169Ring finger protein 169. (589 aa)
pias4Protein inhibitor of activated STAT, 4a. (497 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029925Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSMAMP00000029931Histone H2B; Belongs to the histone H2B family. (129 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
ENSMAMP00000030253Histone H2B; Belongs to the histone H2B family. (153 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (315 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
ENSMAMP00000033310Uncharacterized protein. (533 aa)
ENSMAMP00000033312RAP80_UIM domain-containing protein. (151 aa)
ENSMAMP00000033998BRCA1/BRCA2-containing complex, subunit 3. (264 aa)
ppp4r2Protein phosphatase 4, regulatory subunit 2b. (422 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
LOC113145321Uncharacterized protein. (411 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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