STRINGSTRING
chek1 chek1 rpa2 rpa2 LOC113145149 LOC113145149 kxd1 kxd1 ENSMAMP00000011048 ENSMAMP00000011048 pin1 pin1 ENSMAMP00000011414 ENSMAMP00000011414 LOC113130646 LOC113130646 ENSMAMP00000012442 ENSMAMP00000012442 ENSMAMP00000012848 ENSMAMP00000012848 LOC113129823 LOC113129823 aurka aurka ENSMAMP00000014182 ENSMAMP00000014182 ENSMAMP00000014716 ENSMAMP00000014716 stk11 stk11 ENSMAMP00000014978 ENSMAMP00000014978 cdca7l cdca7l tp53inp2 tp53inp2 mre11 mre11 PRKAB2 PRKAB2 ENSMAMP00000015820 ENSMAMP00000015820 LOC113145054 LOC113145054 slf1 slf1 supt16h supt16h ENSMAMP00000017450 ENSMAMP00000017450 ENSMAMP00000018804 ENSMAMP00000018804 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 RFC2 RFC2 LOC113133909 LOC113133909 nbn nbn ENSMAMP00000019766 ENSMAMP00000019766 ENSMAMP00000019794 ENSMAMP00000019794 ENSMAMP00000019977 ENSMAMP00000019977 ENSMAMP00000020474 ENSMAMP00000020474 ccna1 ccna1 cdk5r2 cdk5r2 ENSMAMP00000021732 ENSMAMP00000021732 tpx2 tpx2 LOC113132426 LOC113132426 rhno1 rhno1 ENSMAMP00000022264 ENSMAMP00000022264 csnk2a2 csnk2a2 ENSMAMP00000022450 ENSMAMP00000022450 LOC113122722 LOC113122722 recql4 recql4 taf6 taf6 ENSMAMP00000035994 ENSMAMP00000035994 TAF4 TAF4 nuak2 nuak2 LOC113130193 LOC113130193 taf3 taf3 nuak1 nuak1 LOC113127152 LOC113127152 rps27a rps27a ENSMAMP00000033029 ENSMAMP00000033029 hus1 hus1 rad50 rad50 ENSMAMP00000030464 ENSMAMP00000030464 ENSMAMP00000023615 ENSMAMP00000023615 brca1 brca1 cdk5 cdk5 LOC113132627 LOC113132627 prkaa2 prkaa2 tbpl1 tbpl1 kat5 kat5 LOC113130355 LOC113130355 taf13 taf13 LOC113141344 LOC113141344 dyrk4 dyrk4 rad17 rad17 LOC113137880 LOC113137880 rpa1 rpa1 ENSMAMP00000026820 ENSMAMP00000026820 mdm2 mdm2 taf10 taf10 ENSMAMP00000027377 ENSMAMP00000027377 prkaa1 prkaa1 tp53inp1 tp53inp1 ENSMAMP00000010386 ENSMAMP00000010386 ENSMAMP00000028195 ENSMAMP00000028195 dyrk2 dyrk2 mapkapk5 mapkapk5 ENSMAMP00000028909 ENSMAMP00000028909 RPA1 RPA1 DNA2 DNA2 taf7l taf7l hipk3 hipk3 tbp tbp exd2 exd2 ENSMAMP00000000596 ENSMAMP00000000596 ENSMAMP00000000716 ENSMAMP00000000716 rpa3 rpa3 LOC113143161 LOC113143161 hipk2 hipk2 ENSMAMP00000002525 ENSMAMP00000002525 ENSMAMP00000002543 ENSMAMP00000002543 atrip atrip ankrd11 ankrd11 rmi1 rmi1 rad9a rad9a ENSMAMP00000002715 ENSMAMP00000002715 ssrp1 ssrp1 LOC113138853 LOC113138853 rmi2 rmi2 LOC113126808 LOC113126808 LOC113125452 LOC113125452 ENSMAMP00000005495 ENSMAMP00000005495 tdrd3 tdrd3 LOC113124961 LOC113124961 rfc5 rfc5 ENSMAMP00000006850 ENSMAMP00000006850 LOC113145174 LOC113145174 LOC113122138 LOC113122138 ENSMAMP00000007755 ENSMAMP00000007755 taf2 taf2 cdk2 cdk2 cdca7 cdca7 meiob meiob LOC113134865 LOC113134865 uba52 uba52 ENSMAMP00000009469 ENSMAMP00000009469 top3a top3a cdk5r1 cdk5r1 ankrd12 ankrd12 rfc4 rfc4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (490 aa)
rpa2Replication protein A2. (272 aa)
LOC113145149Mitogen-activated protein kinase. (364 aa)
kxd1KxDL motif containing 1. (184 aa)
ENSMAMP00000011048Uncharacterized protein. (139 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (156 aa)
ENSMAMP00000011414Exonuclease 1. (740 aa)
LOC113130646Dual specificity tyrosine phosphorylation regulated kinase 3. (603 aa)
ENSMAMP00000012442MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (496 aa)
ENSMAMP00000012848BLM RecQ like helicase. (1366 aa)
LOC113129823Mitogen-activated protein kinase. (361 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (425 aa)
ENSMAMP00000014182TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (765 aa)
ENSMAMP00000014716NOC2-like nucleolar associated transcriptional repressor. (736 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
ENSMAMP00000014978Si:ch211-117c9.1. (659 aa)
cdca7lCell division cycle associated 7b. (409 aa)
tp53inp2Uncharacterized protein. (319 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (268 aa)
ENSMAMP00000015820DNA topoisomerase II binding protein 1. (1389 aa)
LOC113145054Mitogen-activated protein kinase. (360 aa)
slf1SMC5-SMC6 complex localization factor 1. (879 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1029 aa)
ENSMAMP00000017450Uncharacterized protein. (358 aa)
ENSMAMP00000018804Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (441 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
LOC113133909Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (546 aa)
nbnNibrin. (845 aa)
ENSMAMP00000019766P53_tetramer domain-containing protein. (193 aa)
ENSMAMP00000019794WD_REPEATS_REGION domain-containing protein. (565 aa)
ENSMAMP00000019977TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (560 aa)
ENSMAMP00000020474Transcription initiation factor TFIID subunit. (1917 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)
cdk5r2Cyclin-dependent kinase 5 activator. (303 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
tpx2TPX2 microtubule nucleation factor. (723 aa)
LOC113132426Protein kinase domain-containing protein. (1374 aa)
rhno1Si:ch73-352p4.5. (294 aa)
ENSMAMP00000022264RAD1 homolog (S. pombe). (332 aa)
csnk2a2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (350 aa)
ENSMAMP00000022450Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (232 aa)
LOC113122722Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
recql4RecQ helicase-like 4. (1548 aa)
taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
ENSMAMP00000035994TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (227 aa)
TAF4TATA-box binding protein associated factor 4. (1016 aa)
nuak2NUAK family, SNF1-like kinase, 2. (623 aa)
LOC113130193Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (393 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (936 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (657 aa)
LOC113127152Uncharacterized protein. (335 aa)
rps27aRibosomal protein S27a. (156 aa)
ENSMAMP00000033029Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (341 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (315 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
ENSMAMP00000030464TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (825 aa)
ENSMAMP00000023615Cyclin A2; Belongs to the cyclin family. (423 aa)
brca1Uncharacterized protein. (1442 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC113132627Si:dkey-219c3.2. (986 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
tbpl1TBP-like 1. (187 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa)
LOC113130355Si:ch211-160o17.4. (1137 aa)
taf13TATA-box binding protein associated factor 13. (124 aa)
LOC113141344Cyclin-dependent kinase 5 activator. (335 aa)
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (649 aa)
rad17RAD17 checkpoint clamp loader component. (636 aa)
LOC113137880Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (350 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ENSMAMP00000026820SAE2 domain-containing protein. (90 aa)
mdm2MDM2 proto-oncogene. (501 aa)
taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
ENSMAMP00000027377Uncharacterized protein. (298 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (281 aa)
ENSMAMP00000010386TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (156 aa)
ENSMAMP00000028195Aurora kinase B; Belongs to the protein kinase superfamily. (293 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (590 aa)
mapkapk5MAPK activated protein kinase 5. (480 aa)
ENSMAMP00000028909Checkpoint kinase 2. (636 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (362 aa)
hipk3Homeodomain interacting protein kinase 3b. (1322 aa)
tbpTATA box binding protein. (301 aa)
exd2Exonuclease 3'-5' domain containing 2. (644 aa)
ENSMAMP00000000596TP53 regulating kinase. (244 aa)
ENSMAMP00000000716Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (351 aa)
rpa3Replication protein A3. (122 aa)
LOC113143161TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (247 aa)
hipk2Homeodomain interacting protein kinase 2. (1256 aa)
ENSMAMP00000002525Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (388 aa)
ENSMAMP00000002543Mitogen-activated protein kinase. (358 aa)
atripUncharacterized protein. (812 aa)
ankrd11Ankyrin repeat domain 11. (2837 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
ENSMAMP00000002715ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (705 aa)
LOC113138853Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (296 aa)
rmi2RecQ mediated genome instability 2. (138 aa)
LOC113126808Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
LOC113125452Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
ENSMAMP00000005495Non-specific serine/threonine protein kinase. (3067 aa)
tdrd3Tudor domain containing 3. (785 aa)
LOC113124961Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSMAMP00000006850Uncharacterized protein. (86 aa)
LOC113145174Homeodomain interacting protein kinase 1a. (1109 aa)
LOC113122138TAFH domain-containing protein. (1073 aa)
ENSMAMP00000007755Protein kinase domain-containing protein. (164 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1213 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
cdca7Cell division cycle associated 7a. (400 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
LOC113134865Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ENSMAMP00000009469TATA box binding protein like 2. (250 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa)
cdk5r1Cyclin-dependent kinase 5 activator. (302 aa)
ankrd12Ankyrin repeat domain 12. (1938 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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