STRINGSTRING
ENSMAMP00000007077 ENSMAMP00000007077 pole4 pole4 LOC113129257 LOC113129257 mcm10 mcm10 LOC113128348 LOC113128348 mcm9 mcm9 rpa3 rpa3 pola2 pola2 prim1 prim1 pola1 pola1 orc4 orc4 ENSMAMP00000033281 ENSMAMP00000033281 RPA1 RPA1 mcm7 mcm7 rpa1 rpa1 pole3 pole3 ENSMAMP00000025964 ENSMAMP00000025964 orc2 orc2 mcm4 mcm4 prim2 prim2 orc1 orc1 pole pole cdc45 cdc45 gmnn gmnn LOC113132371 LOC113132371 orc5 orc5 mcm2 mcm2 dbf4 dbf4 cdt1 cdt1 mcm5 mcm5 orc3 orc3 rpa2 rpa2 mcm3 mcm3 pole2 pole2 meiob meiob cdk2 cdk2 ENSMAMP00000007755 ENSMAMP00000007755
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAMP00000007077Cell division cycle 7 homolog (S. cerevisiae). (580 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa)
LOC113129257SCY domain-containing protein. (124 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (949 aa)
LOC113128348Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (585 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1316 aa)
rpa3Replication protein A3. (122 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
pola1DNA polymerase. (1480 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
ENSMAMP00000033281Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (785 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa)
ENSMAMP00000025964DNA helicase; Belongs to the MCM family. (825 aa)
orc2Origin recognition complex, subunit 2. (574 aa)
mcm4DNA helicase; Belongs to the MCM family. (878 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (540 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (898 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
gmnnGeminin DNA replication inhibitor. (226 aa)
LOC113132371Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (584 aa)
orc5Origin recognition complex, subunit 5. (444 aa)
mcm2DNA helicase; Belongs to the MCM family. (890 aa)
dbf4DBF4 zinc finger. (628 aa)
cdt1Chromatin licensing and DNA replication factor 1. (661 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
orc3Origin recognition complex, subunit 3. (722 aa)
rpa2Replication protein A2. (272 aa)
mcm3DNA helicase; Belongs to the MCM family. (814 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
ENSMAMP00000007755Protein kinase domain-containing protein. (164 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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