Your Input: | |
| | meiob | Methionine sulfoxide reductase B1b. (469 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1938 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (376 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (373 aa) |
| | rpa2 | Replication protein A2. (272 aa) |
| | ENSMAMP00000011414 | Exonuclease 1. (740 aa) |
| | cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) |
| | ENSMAMP00000012848 | BLM RecQ like helicase. (1366 aa) |
| | ywhaq | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (250 aa) |
| | ENSMAMP00000014297 | Reverse transcriptase domain-containing protein. (699 aa) |
| | LOC113142143 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | cdca7l | Cell division cycle associated 7b. (409 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa) |
| | ENSMAMP00000015732 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | ENSMAMP00000015820 | DNA topoisomerase II binding protein 1. (1389 aa) |
| | ENSMAMP00000016271 | Reverse transcriptase domain-containing protein. (293 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | ENSMAMP00000016919 | Histone H2A; Belongs to the histone H2A family. (136 aa) |
| | LOC113132336 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) |
| | ENSMAMP00000018168 | annotation not available (93 aa) |
| | ENSMAMP00000018386 | Abraxas 1, BRCA1 A complex subunit. (336 aa) |
| | LOC113130787 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | ENSMAMP00000018993 | ATPase_AAA_core domain-containing protein. (157 aa) |
| | ENSMAMP00000019030 | ATPase_AAA_core domain-containing protein. (97 aa) |
| | ENSMAMP00000019064 | ATPase_AAA_core domain-containing protein. (146 aa) |
| | RFC2 | Replication factor C (activator 1) 2. (359 aa) |
| | nbn | Nibrin. (845 aa) |
| | ENSMAMP00000019646 | Reverse transcriptase domain-containing protein. (271 aa) |
| | ENSMAMP00000019766 | P53_tetramer domain-containing protein. (193 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | LOC113126353 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (251 aa) |
| | ENSMAMP00000021732 | Replication factor C (activator 1) 3. (423 aa) |
| | rhno1 | Si:ch73-352p4.5. (294 aa) |
| | ENSMAMP00000022246 | Reverse transcriptase domain-containing protein. (271 aa) |
| | ENSMAMP00000022264 | RAD1 homolog (S. pombe). (332 aa) |
| | ENSMAMP00000022465 | Reverse transcriptase domain-containing protein. (357 aa) |
| | recql4 | RecQ helicase-like 4. (1548 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | brca1 | Uncharacterized protein. (1442 aa) |
| | ENSMAMP00000023704 | Histone H2B; Belongs to the histone H2B family. (132 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (636 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | ENSMAMP00000026820 | SAE2 domain-containing protein. (90 aa) |
| | LOC113144783 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (490 aa) |
| | rnf169 | Ring finger protein 169. (589 aa) |
| | ENSMAMP00000028909 | Checkpoint kinase 2. (636 aa) |
| | tdrd3 | Tudor domain containing 3. (785 aa) |
| | mdc1 | Uncharacterized protein. (1884 aa) |
| | ENSMAMP00000005495 | Non-specific serine/threonine protein kinase. (3067 aa) |
| | LOC113125452 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | ENSMAMP00000003996 | Uncharacterized protein; Belongs to the histone H2B family. (157 aa) |
| | rmi2 | RecQ mediated genome instability 2. (138 aa) |
| | LOC113142818 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa) |
| | ENSMAMP00000002715 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2837 aa) |
| | atrip | Uncharacterized protein. (812 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (396 aa) |
| | LOC113142797 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSMAMP00000002197 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (156 aa) |
| | ENSMAMP00000001831 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | ENSMAMP00000001732 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | ENSMAMP00000001719 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (148 aa) |
| | ENSMAMP00000001553 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | LOC113128524 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | ENSMAMP00000000758 | Wee1-like protein kinase. (551 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (644 aa) |
| | CDC25B | Cell division cycle 25B. (575 aa) |
| | ENSMAMP00000000117 | Nuclear receptor binding SET domain protein 2. (1285 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (497 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa) |
| | ENSMAMP00000029925 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | ENSMAMP00000029931 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1400 aa) |
| | ENSMAMP00000030253 | Histone H2B; Belongs to the histone H2B family. (153 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (315 aa) |
| | ENSMAMP00000033310 | Uncharacterized protein. (533 aa) |
| | ENSMAMP00000033312 | RAP80_UIM domain-containing protein. (151 aa) |
| | ENSMAMP00000033998 | BRCA1/BRCA2-containing complex, subunit 3. (264 aa) |
| | wee1 | Wee1-like protein kinase. (620 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | LOC113122469 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (534 aa) |
| | LOC113125671 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa) |
| | cdca7 | Cell division cycle associated 7a. (400 aa) |
| | ube2n | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | LOC113142845 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (246 aa) |
