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| | wee1 | Wee1-like protein kinase. (620 aa) |
| | ENSMAMP00000034198 | Proteasome endopeptidase complex. (273 aa) |
| | LOC113133570 | Proteasome subunit alpha type. (261 aa) |
| | psmc2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | ENSMAMP00000000117 | Nuclear receptor binding SET domain protein 2. (1285 aa) |
| | CDC25B | Cell division cycle 25B. (575 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (644 aa) |
| | ENSMAMP00000000758 | Wee1-like protein kinase. (551 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | psma2 | Proteasome subunit alpha type. (234 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1316 aa) |
| | ENSMAMP00000001202 | DUF3437 domain-containing protein. (103 aa) |
| | LOC113128524 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | LOC113128348 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (585 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (949 aa) |
| | psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa) |
| | ENSMAMP00000001553 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSMAMP00000001719 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (148 aa) |
| | ENSMAMP00000001732 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | psmc6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | ENSMAMP00000001831 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa) |
| | ENSMAMP00000002197 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (156 aa) |
| | LOC113142797 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (396 aa) |
| | atrip | Uncharacterized protein. (812 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2837 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (698 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | ENSMAMP00000002715 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2574 aa) |
| | LOC113142818 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa) |
| | ENSMAMP00000003030 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (363 aa) |
| | rmi2 | RecQ mediated genome instability 2. (138 aa) |
| | ENSMAMP00000003996 | Uncharacterized protein; Belongs to the histone H2B family. (157 aa) |
| | LOC113125452 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | ENSMAMP00000005495 | Non-specific serine/threonine protein kinase. (3067 aa) |
| | mdc1 | Uncharacterized protein. (1884 aa) |
| | CLSPN | Claspin. (1288 aa) |
| | tdrd3 | Tudor domain containing 3. (785 aa) |
| | psmb2 | Proteasome subunit beta. (199 aa) |
| | wdr41 | WD repeat domain 41. (450 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | LOC113122469 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (534 aa) |
| | ENSMAMP00000007077 | Cell division cycle 7 homolog (S. cerevisiae). (580 aa) |
| | LOC113125671 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa) |
| | psmd14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | psmb3 | Proteasome subunit beta. (205 aa) |
| | ENSMAMP00000007755 | Protein kinase domain-containing protein. (164 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | cdca7 | Cell division cycle associated 7a. (400 aa) |
| | ube2n | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | psme3 | Proteasome activator subunit 3. (256 aa) |
| | LOC113142845 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (246 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (469 aa) |
| | ENSMAMP00000033310 | Uncharacterized protein. (533 aa) |
| | ccnb3 | Cyclin B3; Belongs to the cyclin family. (448 aa) |
| | ENSMAMP00000015820 | DNA topoisomerase II binding protein 1. (1389 aa) |
| | ENSMAMP00000015732 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa) |
| | cdca7l | Cell division cycle associated 7b. (409 aa) |
| | LOC113142143 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | ENSMAMP00000014297 | Reverse transcriptase domain-containing protein. (699 aa) |
| | psmc4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa) |
| | ENSMAMP00000013187 | Piezo-type mechanosensitive ion channel component. (2282 aa) |
| | ywhaq | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (250 aa) |
| | ENSMAMP00000012848 | BLM RecQ like helicase. (1366 aa) |
| | psme1 | Proteasome activator subunit 1. (247 aa) |
| | ENSMAMP00000012512 | Proteasome subunit alpha type. (242 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) |
| | psmc1 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa) |
| | LOC113137626 | Proteasome subunit alpha type. (246 aa) |
| | orc3 | Origin recognition complex, subunit 3. (722 aa) |
| | ENSMAMP00000011414 | Exonuclease 1. (740 aa) |
| | ENSMAMP00000011048 | Uncharacterized protein. (139 aa) |
| | kxd1 | KxDL motif containing 1. (184 aa) |
| | rpa2 | Replication protein A2. (272 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (373 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (376 aa) |
| | PIEZO2 | Piezo-type mechanosensitive ion channel component. (3031 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (814 aa) |
| | psmd7 | Proteasome 26S subunit, non-ATPase 7. (328 aa) |
| | psma3 | Proteasome subunit alpha type. (255 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1938 aa) |
| | LOC113135875 | Proteasome 26S subunit, non-ATPase 11b. (422 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1034 aa) |
| | ENSMAMP00000030253 | Histone H2B; Belongs to the histone H2B family. (153 aa) |
| | psmb1 | Proteasome subunit beta. (237 aa) |
| | ENSMAMP00000030097 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (448 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1400 aa) |
| | ENSMAMP00000029931 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | ENSMAMP00000029925 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa) |
| | ENSMAMP00000029439 | Proteasome 26S subunit, non-ATPase 6. (402 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (497 aa) |
| | ENSMAMP00000028909 | Checkpoint kinase 2. (636 aa) |
| | ENSMAMP00000028424 | Proteasome subunit beta. (275 aa) |
| | rnf169 | Ring finger protein 169. (589 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (490 aa) |
| | LOC113144783 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) |
| | ENSMAMP00000027624 | Piezo_RRas_bdg domain-containing protein. (357 aa) |
| | ENSMAMP00000027586 | PIEZO domain-containing protein. (431 aa) |
| | ENSMAMP00000026820 | SAE2 domain-containing protein. (90 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | psmd9 | Proteasome 26S subunit, non-ATPase 9. (212 aa) |
| | psmd13 | Proteasome 26S subunit, non-ATPase 13. (378 aa) |
| | psmd5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (636 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (394 aa) |
| | LOC113141409 | PCI domain-containing protein. (422 aa) |
| | ENSMAMP00000025964 | DNA helicase; Belongs to the MCM family. (825 aa) |
| | ENSMAMP00000025760 | Uncharacterized protein. (607 aa) |
| | ENSMAMP00000025722 | Uncharacterized protein. (303 aa) |
| | orc2 | Origin recognition complex, subunit 2. (574 aa) |
| | LOC113137975 | Cyclin B2; Belongs to the cyclin family. (402 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (562 aa) |
| | LOC113126771 | Proteasome 26S subunit, non-ATPase 4a. (368 aa) |
| | psmd12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | ENSMAMP00000023704 | Histone H2B; Belongs to the histone H2B family. (132 aa) |
| | brca1 | Uncharacterized protein. (1442 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (878 aa) |
| | recql4 | RecQ helicase-like 4. (1548 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (898 aa) |
| | ENSMAMP00000022465 | Reverse transcriptase domain-containing protein. (357 aa) |
| | ENSMAMP00000022264 | RAD1 homolog (S. pombe). (332 aa) |
| | ENSMAMP00000022246 | Reverse transcriptase domain-containing protein. (271 aa) |
| | rhno1 | Si:ch73-352p4.5. (294 aa) |
| | ENSMAMP00000022053 | Proteasome subunit beta. (271 aa) |
| | ENSMAMP00000022044 | Proteasome subunit beta. (311 aa) |
| | ENSMAMP00000021732 | Replication factor C (activator 1) 3. (423 aa) |
| | LOC113126353 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (251 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | ENSMAMP00000021285 | Proteasome subunit beta 9a. (160 aa) |
| | LOC113126464 | Proteasome subunit beta 12. (217 aa) |
| | psmb8 | Proteasome subunit beta. (278 aa) |
| | psmc5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | LOC113138093 | Proteasome subunit alpha type. (287 aa) |
| | psmd8 | Proteasome 26S subunit, non-ATPase 8. (300 aa) |
| | psma8 | Proteasome subunit alpha type. (251 aa) |
| | LOC113132371 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (584 aa) |
| | orc5 | Origin recognition complex, subunit 5. (444 aa) |
| | psmd10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | LOC113136843 | Proteasome 26S subunit, non-ATPase 4b. (372 aa) |
| | pkmyt1 | Protein kinase, membrane associated tyrosine/threonine 1. (592 aa) |
| | ENSMAMP00000019773 | Proteasome subunit beta11b. (359 aa) |
| | ENSMAMP00000019766 | P53_tetramer domain-containing protein. (193 aa) |
| | psmf1 | Proteasome inhibitor subunit 1. (276 aa) |
| | ENSMAMP00000019698 | Proteasome endopeptidase complex. (253 aa) |
| | ENSMAMP00000019646 | Reverse transcriptase domain-containing protein. (271 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | nbn | Nibrin. (845 aa) |
| | dbf4 | DBF4 zinc finger. (628 aa) |
| | psme2 | Proteasome activator subunit 2. (245 aa) |
| | RFC2 | Replication factor C (activator 1) 2. (359 aa) |
| | ENSMAMP00000019064 | ATPase_AAA_core domain-containing protein. (146 aa) |
| | ENSMAMP00000019030 | ATPase_AAA_core domain-containing protein. (97 aa) |
| | ENSMAMP00000018993 | ATPase_AAA_core domain-containing protein. (157 aa) |
| | LOC113130787 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | LOC113133749 | Proteasome subunit alpha type. (246 aa) |
| | ENSMAMP00000018386 | Abraxas 1, BRCA1 A complex subunit. (336 aa) |
| | ENSMAMP00000018168 | annotation not available (93 aa) |
| | psmd3 | Proteasome 26S subunit, non-ATPase 3. (517 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) |
| | rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | LOC113132336 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | ENSMAMP00000016919 | Histone H2A; Belongs to the histone H2A family. (136 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | LOC113140726 | Proteasome subunit beta. (233 aa) |
| | ENSMAMP00000016271 | Reverse transcriptase domain-containing protein. (293 aa) |
| | ENSMAMP00000033281 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (785 aa) |
| | psmb4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (261 aa) |
| | LOC113127185 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa) |
| | ENSMAMP00000032217 | Proteasome activator subunit 4a. (1746 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (315 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | ENSMAMP00000033312 | RAP80_UIM domain-containing protein. (151 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | LOC113124457 | Proteasome subunit beta. (303 aa) |
| | ENSMAMP00000033998 | BRCA1/BRCA2-containing complex, subunit 3. (264 aa) |
