STRINGSTRING
pola2 pola2 exd2 exd2 LOC113125735 LOC113125735 LOC113128061 LOC113128061 mis18a mis18a daxx daxx ENSMAMP00000021069 ENSMAMP00000021069 ccna1 ccna1 smarca5 smarca5 rtel1 rtel1 ENSMAMP00000021732 ENSMAMP00000021732 terf2ip terf2ip pcna pcna cenpw cenpw LOC113121578 LOC113121578 ENSMAMP00000022783 ENSMAMP00000022783 prim2 prim2 recql4 recql4 ENSMAMP00000023615 ENSMAMP00000023615 ENSMAMP00000023704 ENSMAMP00000023704 ENSMAMP00000024197 ENSMAMP00000024197 CENPS CENPS ENSMAMP00000024977 ENSMAMP00000024977 RCBTB1 RCBTB1 gar1 gar1 rpa1 rpa1 RSF1 RSF1 CENPA CENPA PPP6C PPP6C ENSMAMP00000029072 ENSMAMP00000029072 RPA1 RPA1 ENSMAMP00000029925 ENSMAMP00000029925 ENSMAMP00000029931 ENSMAMP00000029931 ENSMAMP00000029947 ENSMAMP00000029947 DNA2 DNA2 LOC113146398 LOC113146398 ENSMAMP00000030243 ENSMAMP00000030243 cenpi cenpi ENSMAMP00000030253 ENSMAMP00000030253 cenpn cenpn ENSMAMP00000030901 ENSMAMP00000030901 ENSMAMP00000031984 ENSMAMP00000031984 LOC113127185 LOC113127185 fen1 fen1 ENSMAMP00000032975 ENSMAMP00000032975 nhp2 nhp2 LOC113124993 LOC113124993 ENSMAMP00000033957 ENSMAMP00000033957 pola1 pola1 shq1 shq1 ruvbl1 ruvbl1 dscc1 dscc1 prim1 prim1 rpa3 rpa3 LOC113128524 LOC113128524 cenpp cenpp ENSMAMP00000001553 ENSMAMP00000001553 ENSMAMP00000001732 ENSMAMP00000001732 ENSMAMP00000001831 ENSMAMP00000001831 ENSMAMP00000002197 ENSMAMP00000002197 mis18bp1 mis18bp1 LOC113142649 LOC113142649 LOC113142796 LOC113142796 knl1 knl1 LOC113121998 LOC113121998 LOC113142797 LOC113142797 pold1 pold1 ENSMAMP00000002489 ENSMAMP00000002489 LOC113125622 LOC113125622 ankrd52 ankrd52 ENSMAMP00000003224 ENSMAMP00000003224 ENSMAMP00000003996 ENSMAMP00000003996 cenpq cenpq pold4 pold4 LOC113138449 LOC113138449 cenpm cenpm ENSMAMP00000006136 ENSMAMP00000006136 ENSMAMP00000006478 ENSMAMP00000006478 rfc5 rfc5 ENSMAMP00000007755 ENSMAMP00000007755 ENSMAMP00000007985 ENSMAMP00000007985 ruvbl2 ruvbl2 PIF1 PIF1 cdk2 cdk2 LOC113130481 LOC113130481 RBBP4 RBBP4 meiob meiob tert tert rfc4 rfc4 rpa2 rpa2 pold2 pold2 wrap53 wrap53 LOC113132084 LOC113132084 ENSMAMP00000012848 ENSMAMP00000012848 chtf18 chtf18 ENSMAMP00000013291 ENSMAMP00000013291 atrx atrx ENSMAMP00000013775 ENSMAMP00000013775 LOC113126049 LOC113126049 cenpk cenpk ENSMAMP00000015054 ENSMAMP00000015054 ENSMAMP00000015732 ENSMAMP00000015732 pold3 pold3 ENSMAMP00000016350 ENSMAMP00000016350 ENSMAMP00000016385 ENSMAMP00000016385 ENSMAMP00000016724 ENSMAMP00000016724 ENSMAMP00000016760 ENSMAMP00000016760 ENSMAMP00000016811 ENSMAMP00000016811 ENSMAMP00000016915 ENSMAMP00000016915 ENSMAMP00000016919 ENSMAMP00000016919 LOC113122128 LOC113122128 nop10 nop10 LOC113132336 LOC113132336 rcbtb2 rcbtb2 chtf8 chtf8 ENSMAMP00000018103 ENSMAMP00000018103 ENSMAMP00000018114 ENSMAMP00000018114 ENSMAMP00000018168 ENSMAMP00000018168 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 RFC2 RFC2 ENSMAMP00000019218 ENSMAMP00000019218
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
exd2Exonuclease 3'-5' domain containing 2. (644 aa)
LOC113125735Mis18 domain-containing protein. (177 aa)
LOC113128061Ankyrin repeat domain 66. (156 aa)
mis18aMIS18 kinetochore protein A. (190 aa)
daxxDeath-domain associated protein. (740 aa)
ENSMAMP00000021069Ankyrin repeat domain 28b. (1052 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)
smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1039 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1175 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
terf2ipUncharacterized protein. (755 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
cenpwUncharacterized protein. (75 aa)
LOC113121578TINF2_N domain-containing protein. (585 aa)
ENSMAMP00000022783Nucleophosmin 1b. (220 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (540 aa)
recql4RecQ helicase-like 4. (1548 aa)
ENSMAMP00000023615Cyclin A2; Belongs to the cyclin family. (423 aa)
ENSMAMP00000023704Histone H2B; Belongs to the histone H2B family. (132 aa)
ENSMAMP00000024197Histone H2A; Belongs to the histone H2A family. (136 aa)
CENPSCentromere protein S. (133 aa)
ENSMAMP00000024977TEN1 subunit of CST complex. (144 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (232 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
RSF1PHD-type domain-containing protein. (1448 aa)
CENPACentromere protein A. (144 aa)
PPP6CSerine/threonine-protein phosphatase. (305 aa)
ENSMAMP00000029072Histone H2A; Belongs to the histone H2A family. (138 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029925Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSMAMP00000029931Histone H2B; Belongs to the histone H2B family. (129 aa)
ENSMAMP00000029947Replication factor C subunit 1. (1137 aa)
DNA2DNA replication helicase/nuclease 2. (1400 aa)
LOC113146398HTH myb-type domain-containing protein. (608 aa)
ENSMAMP00000030243Histone H2A; Belongs to the histone H2A family. (134 aa)
cenpiCentromere protein I. (720 aa)
ENSMAMP00000030253Histone H2B; Belongs to the histone H2B family. (153 aa)
cenpnCentromere protein N. (338 aa)
ENSMAMP00000030901Uncharacterized protein. (101 aa)
ENSMAMP00000031984Centromere protein X. (63 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
ENSMAMP00000032975Uncharacterized protein. (86 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (155 aa)
LOC113124993Serine/threonine-protein phosphatase. (305 aa)
ENSMAMP00000033957Protection of telomeres 1 homolog. (805 aa)
pola1DNA polymerase. (1480 aa)
shq1SHQ1, H/ACA ribonucleoprotein assembly factor. (649 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
dscc1DNA replication and sister chromatid cohesion 1. (390 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
rpa3Replication protein A3. (122 aa)
LOC113128524Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
cenppCentromere protein P. (288 aa)
ENSMAMP00000001553Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSMAMP00000001732Histone H2B; Belongs to the histone H2B family. (117 aa)
ENSMAMP00000001831Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
ENSMAMP00000002197Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (156 aa)
mis18bp1SANTA domain-containing protein. (1059 aa)
LOC113142649Remodeling and spacing factor 1b, tandem duplicate 1. (1725 aa)
LOC113142796Histone H2A; Belongs to the histone H2A family. (128 aa)
knl1Knl1_RWD_C domain-containing protein. (1933 aa)
LOC113121998PI-PLC Y-box domain-containing protein. (995 aa)
LOC113142797Histone H2B; Belongs to the histone H2B family. (126 aa)
pold1DNA polymerase. (1119 aa)
ENSMAMP00000002489Histone H2A; Belongs to the histone H2A family. (134 aa)
LOC113125622Histone H2A; Belongs to the histone H2A family. (128 aa)
ankrd52Ankyrin repeat domain 52a. (1077 aa)
ENSMAMP00000003224Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSMAMP00000003996Uncharacterized protein; Belongs to the histone H2B family. (157 aa)
cenpqUncharacterized protein. (290 aa)
pold4Si:dkey-28b4.7. (108 aa)
LOC113138449Histone H2A; Belongs to the histone H2A family. (175 aa)
cenpmProliferation associated nuclear element. (184 aa)
ENSMAMP00000006136Zgc:110269. (348 aa)
ENSMAMP00000006478STN1 subunit of CST complex. (338 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSMAMP00000007755Protein kinase domain-containing protein. (164 aa)
ENSMAMP00000007985Dyskeratosis congenita 1, dyskerin. (447 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (496 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (624 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC113130481ANK_REP_REGION domain-containing protein. (1039 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (426 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1110 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
rpa2Replication protein A2. (272 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
wrap53WD repeat containing, antisense to TP53. (554 aa)
LOC113132084Retinoblastoma binding protein 4. (424 aa)
ENSMAMP00000012848BLM RecQ like helicase. (1366 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (947 aa)
ENSMAMP00000013291DNA ligase. (987 aa)
atrxATRX chromatin remodeler. (2018 aa)
ENSMAMP00000013775Nucleophosmin 1a. (357 aa)
LOC113126049ANK_REP_REGION domain-containing protein. (1109 aa)
cenpkCentromere protein K. (288 aa)
ENSMAMP00000015054Ankyrin repeat domain 44. (981 aa)
ENSMAMP00000015732Histone H2B; Belongs to the histone H2B family. (118 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
ENSMAMP00000016350Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSMAMP00000016385Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSMAMP00000016724Uncharacterized protein. (1090 aa)
ENSMAMP00000016760NOP10 ribonucleoprotein homolog (yeast). (60 aa)
ENSMAMP00000016811Uncharacterized protein. (1097 aa)
ENSMAMP00000016915Uncharacterized protein. (1070 aa)
ENSMAMP00000016919Histone H2A; Belongs to the histone H2A family. (136 aa)
LOC113122128Retinoblastoma binding protein 4, like. (427 aa)
nop10NOP10 ribonucleoprotein homolog (yeast). (64 aa)
LOC113132336Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (135 aa)
ENSMAMP00000018103Uncharacterized protein. (1670 aa)
ENSMAMP00000018114Uncharacterized protein. (493 aa)
ENSMAMP00000018168annotation not available (93 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
ENSMAMP00000019218CENP-H domain-containing protein. (234 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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