STRINGSTRING
ENSMAMP00000035870 ENSMAMP00000035870 rpa3 rpa3 MUTYH MUTYH lig3 lig3 pold1 pold1 ENSMAMP00000003022 ENSMAMP00000003022 ENSMAMP00000004556 ENSMAMP00000004556 pold4 pold4 mpg mpg pole4 pole4 smug1 smug1 ENSMAMP00000006136 ENSMAMP00000006136 ENSMAMP00000006223 ENSMAMP00000006223 rfc5 rfc5 meiob meiob pole2 pole2 rfc4 rfc4 ENSMAMP00000010610 ENSMAMP00000010610 rpa2 rpa2 pold2 pold2 LOC113124613 LOC113124613 parp2 parp2 ENSMAMP00000013291 ENSMAMP00000013291 xrcc1 xrcc1 pold3 pold3 ENSMAMP00000016318 ENSMAMP00000016318 rcbtb2 rcbtb2 NTHL1 NTHL1 ENSMAMP00000018993 ENSMAMP00000018993 ENSMAMP00000019030 ENSMAMP00000019030 ENSMAMP00000019064 ENSMAMP00000019064 RFC2 RFC2 ENSMAMP00000019120 ENSMAMP00000019120 pnkp pnkp ENSMAMP00000019589 ENSMAMP00000019589 ENSMAMP00000020176 ENSMAMP00000020176 polb polb ENSMAMP00000021732 ENSMAMP00000021732 pole pole pcna pcna ung ung RCBTB1 RCBTB1 pole3 pole3 rpa1 rpa1 ENSMAMP00000028361 ENSMAMP00000028361 LOC113135582 LOC113135582 RPA1 RPA1 ENSMAMP00000029947 ENSMAMP00000029947 parp1 parp1 LOC113131871 LOC113131871 LOC113127185 LOC113127185 fen1 fen1 LOC113133528 LOC113133528 LOC113132997 LOC113132997 apex1 apex1 ENSMAMP00000035212 ENSMAMP00000035212 apex2 apex2 parp3 parp3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAMP00000035870Methyl-CpG binding domain protein 4. (175 aa)
rpa3Replication protein A3. (122 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (527 aa)
lig3DNA ligase. (1011 aa)
pold1DNA polymerase. (1119 aa)
ENSMAMP00000003022Uncharacterized protein. (510 aa)
ENSMAMP00000004556Si:ch1073-75f15.2. (92 aa)
pold4Si:dkey-28b4.7. (108 aa)
mpgN-methylpurine DNA glycosylase. (314 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (126 aa)
smug1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (282 aa)
ENSMAMP00000006136Zgc:110269. (348 aa)
ENSMAMP00000006223Si:cabz01080528.1. (716 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
meiobMethionine sulfoxide reductase B1b. (469 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
ENSMAMP00000010610Nei-like DNA glycosylase 1. (455 aa)
rpa2Replication protein A2. (272 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
LOC113124613Poly (ADP-ribose) glycohydrolase, like. (710 aa)
parp2Poly [ADP-ribose] polymerase. (649 aa)
ENSMAMP00000013291DNA ligase. (987 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (630 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (441 aa)
ENSMAMP00000016318Von Willebrand factor A domain containing 5B2. (1046 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (276 aa)
ENSMAMP00000018993ATPase_AAA_core domain-containing protein. (157 aa)
ENSMAMP00000019030ATPase_AAA_core domain-containing protein. (97 aa)
ENSMAMP00000019064ATPase_AAA_core domain-containing protein. (146 aa)
RFC2Replication factor C (activator 1) 2. (359 aa)
ENSMAMP000000191208-oxoguanine DNA glycosylase. (385 aa)
pnkpPolynucleotide kinase 3'-phosphatase. (595 aa)
ENSMAMP00000019589FHA_2 domain-containing protein. (51 aa)
ENSMAMP00000020176ADP-ribosylhydrolase like 2. (403 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
ENSMAMP00000021732Replication factor C (activator 1) 3. (423 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2295 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (300 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (153 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ENSMAMP00000028361Si:dkey-117m1.4. (753 aa)
LOC113135582Uncharacterized protein. (814 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (672 aa)
ENSMAMP00000029947Replication factor C subunit 1. (1137 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1010 aa)
LOC113131871Poly (ADP-ribose) glycohydrolase a. (774 aa)
LOC113127185Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (529 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
LOC113133528Thymine DNA glycosylase, tandem duplicate 1. (453 aa)
LOC113132997Thymine DNA glycosylase, tandem duplicate 2. (398 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (343 aa)
ENSMAMP00000035212ATPase family AAA domain containing 5a. (1802 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (581 aa)
parp3Poly [ADP-ribose] polymerase. (531 aa)
Your Current Organism:
Mastacembelus armatus
NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel
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