STRINGSTRING
OSY43116.1 OSY43116.1 OSY42777.1 OSY42777.1 prcB2 prcB2 choB choB OSY42190.1 OSY42190.1 mpa mpa dop dop pup pup prcB1 prcB1 prcA2 prcA2 pafA pafA crp_1 crp_1 cyaB cyaB OSY39067.1 OSY39067.1 yheS_2 yheS_2 fabG_19 fabG_19 OSY39072.1 OSY39072.1 OSY39073.1 OSY39073.1 nat nat OSY38454.1 OSY38454.1 OSY38391.1 OSY38391.1 crp_2 crp_2 OSY38254.1 OSY38254.1 crp_3 crp_3 OSY37411.1 OSY37411.1 OSY36760.1 OSY36760.1 acuC acuC fdhL_2 fdhL_2 OSY34926.1 OSY34926.1 OSY34388.1 OSY34388.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OSY43116.1DinB superfamily protein. (191 aa)
OSY42777.1Hypothetical protein. (352 aa)
prcB2Proteasome subunit beta 2 precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (263 aa)
choBCholesterol oxidase precursor. (530 aa)
OSY42190.1Hypothetical protein. (185 aa)
mpaProteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (606 aa)
dopPup deamidase/depupylase. (508 aa)
pupProkaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family. (65 aa)
prcB1Proteasome subunit beta 1 precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (296 aa)
prcA2Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (271 aa)
pafAPup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (453 aa)
crp_1cAMP receptor protein. (246 aa)
cyaBAdenylate cyclase 2. (509 aa)
OSY39067.1Putative multidrug export ATP-binding/permease protein. (631 aa)
yheS_2Putative ABC transporter ATP-binding protein YheS. (540 aa)
fabG_193-oxoacyl-[acyl-carrier-protein] reductase FabG. (258 aa)
OSY39072.1Universal stress protein/MT1672. (149 aa)
OSY39073.1pH-sensitive adenylate cyclase. (347 aa)
natArylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family. (321 aa)
OSY38454.1Hypothetical protein. (583 aa)
OSY38391.1Hypothetical protein. (277 aa)
crp_2cAMP receptor protein. (253 aa)
OSY38254.1Calcineurin-like phosphoesterase superfamily domain protein. (148 aa)
crp_3cAMP receptor protein. (224 aa)
OSY37411.1Calcineurin-like phosphoesterase. (290 aa)
OSY36760.1Acetyltransferase Pat. (903 aa)
acuCAcetoin utilization protein AcuC. (390 aa)
fdhL_2Fructose dehydrogenase large subunit. (549 aa)
OSY34926.1WD domain, G-beta repeat. (755 aa)
OSY34388.1Hypothetical protein. (344 aa)
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
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