(16 nodes) Mixed, incl. Fructose transmembrane transport, and Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 network (Enterobacter kobei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OLR19186.1	Transcriptional regulator; Repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
	OLR19188.1	PTS subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
	OLR19189.1	PTS fructose transporter subunit IIA; With FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
	OLR19194.1	PTS sugar transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
	OLR19195.1	PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
	OLR19738.1	PTS mannitol transporter subunit IIBC; CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
	OLR20212.1	PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
	OLR20213.1	PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
	OLR20326.1	PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
	OLR20797.1	6-phosphofructokinase II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (310 aa)
	OLR17710.1	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
	OLR17711.1	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (312 aa)
	OLR17712.1	Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	OLR17717.1	Fructuronate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (488 aa)
	mtlD	Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
	OLR18753.1	PTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)

Your Current Organism:

Enterobacter kobei

NCBI taxonomy Id: 208224
Other names: ATCC BAA-260, CCUG 49023, CIP 105566, DSM 13645, E. kobei, Enterobacter sp. 35730, Enterobacter sp. 42202, Enterobacter sp. 44593, Enterobacter sp. GN02186, Enterobacter sp. GN02204, Enterobacter sp. GN02225, Enterobacter sp. GN02266, Enterobacter sp. GN02275, Enterobacter sp. GN02366, Enterobacter sp. GN02454, Enterobacter sp. GN02825, Enterobacter sp. GN03191, JCM 8580, NIH group 21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLR17710.1	OLR17711.1	BH713_14355	BH713_14360	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	0.999
OLR17710.1	OLR17712.1	BH713_14355	BH713_14365	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLR17710.1	OLR17717.1	BH713_14355	BH713_14390	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructuronate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family.	0.805
OLR17710.1	OLR18753.1	BH713_14355	BH713_20040	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OLR17710.1	OLR19186.1	BH713_14355	BH713_00265	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.966
OLR17710.1	OLR19188.1	BH713_14355	BH713_00275	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.871
OLR17710.1	OLR19189.1	BH713_14355	BH713_00280	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; With FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.969
OLR17710.1	OLR19194.1	BH713_14355	BH713_00305	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS sugar transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
OLR17710.1	OLR19195.1	BH713_14355	BH713_00310	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.794
OLR17710.1	OLR20212.1	BH713_14355	BH713_05920	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.828
OLR17710.1	OLR20213.1	BH713_14355	BH713_05925	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.796
OLR17710.1	OLR20326.1	BH713_14355	BH713_06570	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.935
OLR17710.1	OLR20797.1	BH713_14355	BH713_09150	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-phosphofructokinase II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	0.999
OLR17710.1	mtlD	BH713_14355	BH713_20035	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.805
OLR17711.1	OLR17710.1	BH713_14360	BH713_14355	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OLR17711.1	OLR17712.1	BH713_14360	BH713_14365	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OLR17711.1	OLR18753.1	BH713_14360	BH713_20040	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	PTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
OLR17711.1	OLR19186.1	BH713_14360	BH713_00265	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	Transcriptional regulator; Repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.756
OLR17711.1	OLR19188.1	BH713_14360	BH713_00275	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	PTS subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OLR17711.1	OLR19189.1	BH713_14360	BH713_00280	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	PTS fructose transporter subunit IIA; With FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.787

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