STRINGSTRING
sufE sufE OLR19237.1 OLR19237.1 OLR19376.1 OLR19376.1 OLR19401.1 OLR19401.1 OLR19562.1 OLR19562.1 OLR20089.1 OLR20089.1 OLR20206.1 OLR20206.1 OLR21694.1 OLR21694.1 OLR20493.1 OLR20493.1 selD selD sufS sufS OLR18832.1 OLR18832.1 metE metE selA selA OLR18373.1 OLR18373.1 OLR18286.1 OLR18286.1 BH713_17025 BH713_17025 csdE csdE OLR18152.1 OLR18152.1 cysD cysD cysN cysN OLR17974.1 OLR17974.1 metG metG OLR20949.1 OLR20949.1 BH713_09735 BH713_09735 OLR20873.1 OLR20873.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sufECysteine desufuration protein SufE; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family. (138 aa)
OLR19237.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
OLR19376.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa)
OLR19401.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
OLR19562.1L-seryl-tRNA selenium transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
OLR20089.1Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
OLR20206.1Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
OLR21694.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
OLR20493.1Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
selDSelenide, water dikinase SelD; Synthesizes selenophosphate from selenide and ATP. (347 aa)
sufSBifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (406 aa)
OLR18832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (471 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (753 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (462 aa)
OLR18373.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
OLR18286.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
BH713_17025Cystathionine beta-synthase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
csdECysteine desulfurase, sulfur acceptor subunit CsdE; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
OLR18152.1Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
cysDSulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
cysNSulfate adenylyltransferase subunit CysN; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa)
OLR17974.1Thioredoxin TrxC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (139 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa)
OLR20949.15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
BH713_09735Dimethylsulfoxide reductase, chain B; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (812 aa)
OLR20873.1Transcriptional regulator; Catalyzes the formation of homocysteine and pyruvate from cystathionine; also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
Your Current Organism:
Enterobacter kobei
NCBI taxonomy Id: 208224
Other names: ATCC BAA-260, CCUG 49023, CIP 105566, DSM 13645, E. kobei, Enterobacter sp. 35730, Enterobacter sp. 42202, Enterobacter sp. 44593, Enterobacter sp. GN02186, Enterobacter sp. GN02204, Enterobacter sp. GN02225, Enterobacter sp. GN02266, Enterobacter sp. GN02275, Enterobacter sp. GN02366, Enterobacter sp. GN02454, Enterobacter sp. GN02825, Enterobacter sp. GN03191, JCM 8580, NIH group 21
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