(9 nodes) Butanoate metabolism network (Streptococcus agalactiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SAG1124	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (458 aa)
	SAG1316	HMG-CoA synthase; Identified by match to PFAM protein family HMM PF01154. (390 aa)
	SAG1673	Identified by match to PFAM protein family HMM PF00725. (321 aa)
	pflD-2	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228. (770 aa)
	adhE	Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (880 aa)
	pflD-1	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228. (818 aa)
	SAG0466	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family. (371 aa)
	SAG0523	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106. (254 aa)
	budA	Alpha-acetolactate decarboxylase; Identified by match to PFAM protein family HMM PF03306; Belongs to the alpha-acetolactate decarboxylase family. (239 aa)

Your Current Organism:

Streptococcus agalactiae

NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SAG0466	SAG0523	SAG0466	SAG0523	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	0.560
SAG0466	SAG1124	SAG0466	SAG1124	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.621
SAG0466	SAG1316	SAG0466	SAG1316	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	HMG-CoA synthase; Identified by match to PFAM protein family HMM PF01154.	0.999
SAG0466	SAG1673	SAG0466	SAG1673	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Identified by match to PFAM protein family HMM PF00725.	0.999
SAG0466	adhE	SAG0466	SAG0053	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.912
SAG0466	pflD-1	SAG0466	SAG0331	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228.	0.670
SAG0466	pflD-2	SAG0466	SAG1727	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228.	0.672
SAG0523	SAG0466	SAG0523	SAG0466	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	0.560
SAG0523	SAG1124	SAG0523	SAG1124	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.430
SAG0523	SAG1316	SAG0523	SAG1316	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	HMG-CoA synthase; Identified by match to PFAM protein family HMM PF01154.	0.454
SAG0523	SAG1673	SAG0523	SAG1673	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	Identified by match to PFAM protein family HMM PF00725.	0.541
SAG0523	adhE	SAG0523	SAG0053	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.869
SAG0523	budA	SAG0523	SAG1191	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	Alpha-acetolactate decarboxylase; Identified by match to PFAM protein family HMM PF03306; Belongs to the alpha-acetolactate decarboxylase family.	0.732
SAG1124	SAG0466	SAG1124	SAG0466	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	0.621
SAG1124	SAG0523	SAG1124	SAG0523	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.	0.430
SAG1124	SAG1673	SAG1124	SAG1673	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Identified by match to PFAM protein family HMM PF00725.	0.560
SAG1124	adhE	SAG1124	SAG0053	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.777
SAG1124	pflD-1	SAG1124	SAG0331	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228.	0.436
SAG1124	pflD-2	SAG1124	SAG1727	Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228.	0.436
SAG1316	SAG0466	SAG1316	SAG0466	HMG-CoA synthase; Identified by match to PFAM protein family HMM PF01154.	Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.	0.999