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arcC-2 arcC-2 arsC arsC rpiA rpiA SAG1295 SAG1295 SAG1564 SAG1564 SAG1566 SAG1566 ppdK ppdK SAG1673 SAG1673 pgk pgk gap gap rpe rpe tal tal SAG1853 SAG1853 SAG1889 SAG1889 SAG1905 SAG1905 SAG1906 SAG1906 eda-2 eda-2 SAG2063 SAG2063 SAG2092 SAG2092 arcC-1 arcC-1 sdhB sdhB sdhA sdhA prsA-1 prsA-1 SAG0040 SAG0040 SAG0042 SAG0042 fba fba ackA ackA SAG0199 SAG0199 SAG0200 SAG0200 cysE cysE SAG0223 SAG0223 tkt tkt SAG0324 SAG0324 SAG0332 SAG0332 cysK cysK accB accB accC accC accD accD accA accA pgi pgi SAG0466 SAG0466 glk glk folD folD serB serB eno eno cylF cylF SAG0697 SAG0697 eda-1 eda-1 ppc ppc tpiA tpiA gpmA gpmA gapN gapN SAG0878 SAG0878 SAG0879 SAG0879 SAG0880 SAG0880 SAG0881 SAG0881 pfk pfk pyk pyk spxA spxA fhs fhs SAG1059 SAG1059 glyA glyA SAG1092 SAG1092 prsA-2 prsA-2 neuD neuD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arcC-2Carbamate kinase; Identified by match to PFAM protein family HMM PF00696; Belongs to the carbamate kinase family. (318 aa)
arsCArsenate reductase; Belongs to the ArsC family. (135 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa)
SAG1295Conserved hypothetical protein; Identified by Glimmer2; putative. (127 aa)
SAG1564Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the ArsC family. (118 aa)
SAG1566D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to PFAM protein family HMM PF01842; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (393 aa)
ppdKPyruvate phosphate dikinase; Identified by match to PFAM protein family HMM PF00391; Belongs to the PEP-utilizing enzyme family. (881 aa)
SAG1673Identified by match to PFAM protein family HMM PF00725. (321 aa)
pgkPhosphoglycerate kinase; Identified by match to PFAM protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (398 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; Identified by match to PFAM protein family HMM PF00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
rpeRibulose-phosphate 3-epimerase; Identified by match to PFAM protein family HMM PF00834; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
talTransaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
SAG1853Prophage LambdaSa2, protease, putative; Similar to OMNI:CC2786; identified by sequence similarity; putative. (180 aa)
SAG1889Microcin immunity protein MccF, putative; Identified by match to PFAM protein family HMM PF02016. (317 aa)
SAG1905Conserved hypothetical protein; Identified by Glimmer2; putative. (212 aa)
SAG1906Carbohydrate kinase, PfkB family; Identified by match to PFAM protein family HMM PF00294. (335 aa)
eda-22-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081. (212 aa)
SAG2063Pathogenicity protein, putative; Identified by match to PFAM protein family HMM PF00746. (630 aa)
SAG2092Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the ArsC family. (132 aa)
arcC-1Carbamate kinase; Identified by match to PFAM protein family HMM PF00696; Belongs to the carbamate kinase family. (308 aa)
sdhBL-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to PFAM protein family HMM PF01842; Belongs to the iron-sulfur dependent L-serine dehydratase family. (222 aa)
sdhAL-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by match to PFAM protein family HMM PF03313; Belongs to the iron-sulfur dependent L-serine dehydratase family. (290 aa)
prsA-1Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa)
SAG0040ROK family protein; Identified by match to PFAM protein family HMM PF00480; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. (293 aa)
SAG0042Phosphosugar-binding transcriptional regulator, RpiR family; Identified by match to PFAM protein family HMM PF01380. (267 aa)
fbaFructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116. (293 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
SAG0199Transketolase, N-terminal subunit; Identified by match to PFAM protein family HMM PF00456. (285 aa)
SAG0200Transketolase, C-terminal subunit; Identified by match to PFAM protein family HMM PF02779. (309 aa)
cysESerine O-acetyltransferase; Identified by match to PFAM protein family HMM PF00132. (194 aa)
SAG0223Conserved hypothetical protein, fusion; Identified by Glimmer2; putative. (209 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (661 aa)
SAG0324General stress protein, putative; Identified by match to PFAM protein family HMM PF00575. (124 aa)
SAG0332Identified by match to PFAM protein family HMM PF00923. (222 aa)
cysKCysteine synthase A; Identified by match to PFAM protein family HMM PF00291; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (166 aa)
accCacetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (257 aa)
pgiGlucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342. (449 aa)
SAG0466Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family. (371 aa)
glkGlucokinase; Identified by match to PFAM protein family HMM PF00480. (322 aa)
folDMethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
serBPhosphoserine phosphatase SerB; Identified by match to PFAM protein family HMM PF00702. (213 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
cylFcylF protein; Identified by match to PFAM protein family HMM PF01571; Belongs to the GcvT family. (317 aa)
SAG06972-keto-3-deoxygluconate kinase; Identified by match to PFAM protein family HMM PF00294. (341 aa)
eda-12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081. (205 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (931 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
gpmAPhosphoglycerate mutase family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
gapNGlyceraldehyde-3-phosphate dehydrogenase, NADP-dependent; Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (475 aa)
SAG0878Acetoin dehydrogenase, thymine PPi dependent, E1 component, alpha subunit; Identified by match to PFAM protein family HMM PF00676. (322 aa)
SAG0879Acetoin dehydrogenase, thymine PPi dependent, E1 component, beta subunit; Identified by match to PFAM protein family HMM PF02779. (332 aa)
SAG0880Acetoin dehydrogenase, thymine PPi dependent, E2 component, dihydrolipoamide acetyltransferase; Identified by match to PFAM protein family HMM PF00198. (462 aa)
SAG0881Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070. (585 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (340 aa)
pykPyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family. (500 aa)
spxAConserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (137 aa)
fhsFormate--tetrahydrofolate ligase; Identified by match to PFAM protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
SAG1059Glycine cleavage system H protein, putative; Identified by match to PFAM protein family HMM PF01597. (110 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
SAG1092Phosphate acetyltransferase; Identified by match to PFAM protein family HMM PF01515. (330 aa)
prsA-2Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (324 aa)
neuDneuD protein. (209 aa)
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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