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| | AIG73012.1 | Hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (355 aa) |
| | AIG73138.1 | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa) |
| | AIG73405.1 | Hypothetical protein; Belongs to the CutC family. (225 aa) |
| | mdlC | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. (527 aa) |
| | AIG73420.1 | NAD-dependent malic enzyme. (466 aa) |
| | citA | Putative citrate synthase 2; Belongs to the citrate synthase family. (383 aa) |
| | gltA2 | Citrate synthase 1; Belongs to the citrate synthase family. (438 aa) |
| | AIG73697.1 | Hypothetical protein. (623 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | AIG73971.1 | NAD-dependent malic enzyme. (409 aa) |
| | AIG73980.1 | SMP-30/Gluconolaconase/LRE domain protein. (262 aa) |
| | kgd | Multifunctional 2-oxoglutarate metabolism enzyme. (1240 aa) |
| | AIG74005.1 | Methylcrotonoyl-CoA carboxylase beta chain. (537 aa) |
| | accA1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (661 aa) |
| | ilvX | Putative acetolactate synthase large subunit IlvX. (520 aa) |
| | gabT1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | dmlA | D-malate dehydrogenase [decarboxylating]. (353 aa) |
| | AIG74054.1 | Hypothetical protein; Belongs to the TPP enzyme family. (543 aa) |
| | meaA | Protein MeaA. (673 aa) |
| | AIG74434.1 | Hypothetical protein. (149 aa) |
| | AIG74436.1 | Putative GTPase. (322 aa) |
| | icl | Isocitrate lyase. (428 aa) |
| | aceB1 | Malate synthase; Belongs to the malate synthase family. (534 aa) |
| | ilvD3 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. (614 aa) |
| | ilvB1 | Acetolactate synthase large subunit IlvB1. (624 aa) |
| | ilvH | Acetolactate synthase small subunit. (168 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (347 aa) |
| | AIG74567.1 | Putative AIPM/Hcit synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (541 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa) |
| | lipA1 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (333 aa) |
| | AIG74789.1 | 6-phosphogluconate dehydrogenase. (288 aa) |
| | aceB2 | Malate synthase; Belongs to the malate synthase family. (525 aa) |
| | mtr | Mycothione reductase. (464 aa) |
| | AIG74972.1 | Hypothetical protein. (242 aa) |
| | AIG74974.1 | Hypothetical protein. (464 aa) |
| | lldD | Putative L-lactate dehydrogenase [cytochrome]. (403 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (931 aa) |
| | lipA2 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (333 aa) |
| | lipB | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (247 aa) |
| | AIG75027.1 | Hypothetical protein. (587 aa) |
| | AIG75028.1 | Dihydrolipoyl dehydrogenase. (457 aa) |
| | ilvE | Branched-chain-amino-acid aminotransferase. (367 aa) |
| | AIG75455.1 | Putative tartrate dehydrogenase/decarboxylase. (349 aa) |
| | iolA1 | Methylmalonate semialdehyde dehydrogenase [acylating] 1. (494 aa) |
| | AIG75999.1 | Hypothetical protein. (1149 aa) |
| | AIG76060.1 | Hypothetical protein. (330 aa) |
| | sucD1 | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | sucC1 | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa) |
| | AIG76305.1 | dicarboxylate-CoA ligase PimA. (541 aa) |
| | AIG76479.1 | Hypothetical protein. (397 aa) |
| | bkdB | 3-methyl-2-oxobutanoate dehydrogenase subunit beta. (332 aa) |
| | AIG76481.1 | Hypothetical protein. (362 aa) |
| | AIG76517.1 | Aldehyde dehydrogenase, dimeric NADP-preferring; Belongs to the aldehyde dehydrogenase family. (435 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa) |
| | geoB1 | Geranial dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa) |
| | poxB | Pyruvate dehydrogenase [ubiquinone]; Belongs to the TPP enzyme family. (579 aa) |
| | AIG76774.1 | Hypothetical protein. (170 aa) |
| | acnA | Aconitate hydratase. (935 aa) |
| | AIG76974.1 | Hypothetical protein. (567 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (559 aa) |
| | AIG77158.1 | Hypothetical protein. (471 aa) |
| | AIG77295.1 | Propionyl-CoA carboxylase beta chain. (521 aa) |
| | gabD2a | Putative succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (524 aa) |
| | AIG77597.1 | Thiamine pyrophosphate protein; Belongs to the TPP enzyme family. (596 aa) |
| | AIG77745.1 | Hypothetical protein. (650 aa) |
| | fumA | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (552 aa) |
| | icmF | Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1078 aa) |
| | gabD2b | Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family. (537 aa) |
| | geoB2 | Geranial dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa) |
| | iolA2 | Methylmalonate semialdehyde dehydrogenase [acylating] 2. (498 aa) |
| | AIG78874.1 | Propionyl-CoA carboxylase beta chain. (567 aa) |
| | lpd | Dihydrolipoyl dehydrogenase. (461 aa) |
| | AIG78977.1 | Hypothetical protein. (387 aa) |
| | araC | L-arabonate dehydratase; Belongs to the IlvD/Edd family. (572 aa) |
| | AIG79399.1 | 6-phosphogluconate dehydrogenase. (287 aa) |
| | gabT2 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | AIG79761.1 | biotin-[acetyl-CoA-carboxylase] ligase. (274 aa) |
| | pccB | Propionyl-CoA carboxylase beta chain. (545 aa) |
| | AIG79781.1 | Hypothetical protein. (72 aa) |
| | bccA | Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (596 aa) |
| | AIG79806.1 | Hypothetical protein. (290 aa) |
| | AIG79807.1 | Carboxylate-amine ligase. (432 aa) |
| | AIG79808.1 | Hypothetical protein. (99 aa) |
| | AIG79809.1 | Putative GTPase. (332 aa) |
| | mutB | Methylmalonyl-CoA mutase large subunit. (722 aa) |
| | mutA | Methylmalonyl-CoA mutase small subunit. (625 aa) |
| | AIG79837.1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa) |
| | icd | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa) |
| | sucD2 | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa) |
| | sucC2 | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | AIG79947.1 | Hypothetical protein. (119 aa) |
| | AIG80001.1 | Hypothetical protein. (473 aa) |
| | korA | 2-oxoglutarate oxidoreductase subunit KorA. (635 aa) |
| | korB | 2-oxoglutarate oxidoreductase subunit KorB. (354 aa) |
| | AIG80348.1 | Hypothetical protein; Belongs to the TPP enzyme family. (540 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa) |
| | AIG80748.1 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. (457 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (585 aa) |
| | bkdA | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha. (401 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component subunit beta. (330 aa) |
| | AIG81080.1 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. (446 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa) |
