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AIG73420.1 AIG73420.1 citA citA gltA2 gltA2 fumC fumC AIG73971.1 AIG73971.1 ilvX ilvX icl icl aceB1 aceB1 pyc pyc aceB2 aceB2 lldD lldD aceE aceE AIG75999.1 AIG75999.1 AIG76060.1 AIG76060.1 sucD1 sucD1 sucC1 sucC1 mdh mdh acnA acnA fumA fumA icd icd sucD2 sucD2 sucC2 sucC2 AIG79947.1 AIG79947.1 korA korA korB korB pckG pckG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AIG73420.1NAD-dependent malic enzyme. (466 aa)
citAPutative citrate synthase 2; Belongs to the citrate synthase family. (383 aa)
gltA2Citrate synthase 1; Belongs to the citrate synthase family. (438 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
AIG73971.1NAD-dependent malic enzyme. (409 aa)
ilvXPutative acetolactate synthase large subunit IlvX. (520 aa)
iclIsocitrate lyase. (428 aa)
aceB1Malate synthase; Belongs to the malate synthase family. (534 aa)
pycPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa)
aceB2Malate synthase; Belongs to the malate synthase family. (525 aa)
lldDPutative L-lactate dehydrogenase [cytochrome]. (403 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (931 aa)
AIG75999.1Hypothetical protein. (1149 aa)
AIG76060.1Hypothetical protein. (330 aa)
sucD1Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
sucC1Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
acnAAconitate hydratase. (935 aa)
fumAFumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (552 aa)
icdIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
sucD2Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucC2Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
AIG79947.1Hypothetical protein. (119 aa)
korA2-oxoglutarate oxidoreductase subunit KorA. (635 aa)
korB2-oxoglutarate oxidoreductase subunit KorB. (354 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa)
Your Current Organism:
Amycolatopsis japonica
NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17
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