STRINGSTRING
AIG73142.1 AIG73142.1 AIG80979.1 AIG80979.1 ctaD ctaD nuoN1 nuoN1 AIG80414.1 AIG80414.1 AIG80413.1 AIG80413.1 nuoK-2 nuoK-2 AIG80410.1 AIG80410.1 nuoF nuoF AIG80202.1 AIG80202.1 nuoH nuoH nuoI nuoI nuoK nuoK nuoL nuoL AIG80196.1 AIG80196.1 nuoN nuoN korB korB korA korA sucC2 sucC2 sucD2 sucD2 icd icd sdhB sdhB sdhD sdhD AIG79862.1 AIG79862.1 mutA mutA cydB cydB cydA cydA AIG79648.1 AIG79648.1 AIG78276.1 AIG78276.1 AIG78202.1 AIG78202.1 AIG78201.1 AIG78201.1 ctaD1b ctaD1b AIG77568.1 AIG77568.1 AIG77546.1 AIG77546.1 AIG77067.1 AIG77067.1 acnA acnA AIG76708.1 AIG76708.1 AIG76702.1 AIG76702.1 mdh mdh AIG76261.1 AIG76261.1 sucC1 sucC1 sucD1 sucD1 qcrB qcrB ctaE ctaE AIG75027.1 AIG75027.1 aspA aspA aceB2 aceB2 aceB1 aceB1 icl icl ctaD1a ctaD1a AIG74028.1 AIG74028.1 kgd kgd fumC fumC gltA2 gltA2 citA citA AIG73106.1 AIG73106.1 AIG73105.1 AIG73105.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIG73142.1Hypothetical protein. (398 aa)
AIG80979.1Glycolate oxidase. (963 aa)
ctaDPutative cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (591 aa)
nuoN1NADH-quinone oxidoreductase subunit N 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (471 aa)
AIG80414.1Proton-translocating NADH-quinone oxidoreductase, chain M. (493 aa)
AIG80413.1Hypothetical protein. (610 aa)
nuoK-2Putative membrane protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (101 aa)
AIG80410.1Putative membrane protein. (308 aa)
nuoFNADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (426 aa)
AIG80202.1Hypothetical protein. (839 aa)
nuoHNADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (445 aa)
nuoINADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (181 aa)
nuoKNADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (99 aa)
nuoLNADH-quinone oxidoreductase subunit L. (632 aa)
AIG80196.1Conserved putative membrane protein. (516 aa)
nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (521 aa)
korB2-oxoglutarate oxidoreductase subunit KorB. (354 aa)
korA2-oxoglutarate oxidoreductase subunit KorA. (635 aa)
sucC2Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucD2Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
icdIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
sdhBSuccinate dehydrogenase iron-sulfur protein. (256 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor protein. (139 aa)
AIG79862.1Succinate dehydrogenase, cytochrome b556 subunit. (147 aa)
mutAMethylmalonyl-CoA mutase small subunit. (625 aa)
cydBCytochrome bd-I oxidase subunit II. (330 aa)
cydACytochrome bd-I oxidase subunit I. (392 aa)
AIG79648.1Phosphoesterase. (215 aa)
AIG78276.1Hypothetical protein. (250 aa)
AIG78202.1Hypothetical protein. (136 aa)
AIG78201.1Hypothetical protein. (262 aa)
ctaD1bPutative cytochrome c oxidase subunit 1-alpha; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (564 aa)
AIG77568.1Hypothetical protein. (436 aa)
AIG77546.1Hypothetical protein. (245 aa)
AIG77067.1Hypothetical protein. (102 aa)
acnAAconitate hydratase. (935 aa)
AIG76708.1Hypothetical protein. (68 aa)
AIG76702.1Hypothetical protein. (462 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AIG76261.1Hypothetical protein. (578 aa)
sucC1Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
sucD1Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
qcrBUbiquinol-cytochrome c reductase cytochrome b subunit. (555 aa)
ctaEPutative cytochrome c oxidase subunit 3. (207 aa)
AIG75027.1Hypothetical protein. (587 aa)
aspAAspartate ammonia-lyase. (462 aa)
aceB2Malate synthase; Belongs to the malate synthase family. (525 aa)
aceB1Malate synthase; Belongs to the malate synthase family. (534 aa)
iclIsocitrate lyase. (428 aa)
ctaD1aPutative cytochrome c oxidase subunit 1-alpha; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (592 aa)
AIG74028.1Putative FAD-linked oxidoreductase. (483 aa)
kgdMultifunctional 2-oxoglutarate metabolism enzyme. (1240 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
gltA2Citrate synthase 1; Belongs to the citrate synthase family. (438 aa)
citAPutative citrate synthase 2; Belongs to the citrate synthase family. (383 aa)
AIG73106.1Conserved putative membrane protein. (335 aa)
AIG73105.1Conserved putative membrane protein. (503 aa)
Your Current Organism:
Amycolatopsis japonica
NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.