(4 nodes) Methylmalonyl-CoA mutase, alpha/beta chain, catalytic network (Amycolatopsis japonica)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	meaA	Protein MeaA. (673 aa)
	icmF	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1078 aa)
	mutB	Methylmalonyl-CoA mutase large subunit. (722 aa)
	mutA	Methylmalonyl-CoA mutase small subunit. (625 aa)

Your Current Organism:

Amycolatopsis japonica

NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
icmF	meaA	AJAP_26520	AJAP_06220	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	Protein MeaA.	0.995
icmF	mutA	AJAP_26520	AJAP_35020	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	Methylmalonyl-CoA mutase small subunit.	0.997
icmF	mutB	AJAP_26520	AJAP_35015	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	Methylmalonyl-CoA mutase large subunit.	0.995
meaA	icmF	AJAP_06220	AJAP_26520	Protein MeaA.	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	0.995
meaA	mutA	AJAP_06220	AJAP_35020	Protein MeaA.	Methylmalonyl-CoA mutase small subunit.	0.945
meaA	mutB	AJAP_06220	AJAP_35015	Protein MeaA.	Methylmalonyl-CoA mutase large subunit.	0.935
mutA	icmF	AJAP_35020	AJAP_26520	Methylmalonyl-CoA mutase small subunit.	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	0.997
mutA	meaA	AJAP_35020	AJAP_06220	Methylmalonyl-CoA mutase small subunit.	Protein MeaA.	0.945
mutA	mutB	AJAP_35020	AJAP_35015	Methylmalonyl-CoA mutase small subunit.	Methylmalonyl-CoA mutase large subunit.	0.999
mutB	icmF	AJAP_35015	AJAP_26520	Methylmalonyl-CoA mutase large subunit.	Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.	0.995
mutB	meaA	AJAP_35015	AJAP_06220	Methylmalonyl-CoA mutase large subunit.	Protein MeaA.	0.935
mutB	mutA	AJAP_35015	AJAP_35020	Methylmalonyl-CoA mutase large subunit.	Methylmalonyl-CoA mutase small subunit.	0.999