STRINGSTRING
AIG74060.1 AIG74060.1 AIG72996.1 AIG72996.1 AIG73138.1 AIG73138.1 AIG73150.1 AIG73150.1 AIG73160.1 AIG73160.1 AIG73198.1 AIG73198.1 AIG73204.1 AIG73204.1 pat pat ectB ectB serC serC AIG73613.1 AIG73613.1 AIG73658.1 AIG73658.1 metB metB metY1 metY1 gabT1 gabT1 AIG74189.1 AIG74189.1 kynU kynU dgdA dgdA AIG74440.1 AIG74440.1 iscS iscS AIG74654.1 AIG74654.1 gcvP1 gcvP1 glyA1 glyA1 AIG74734.1 AIG74734.1 metY2 metY2 AIG74901.1 AIG74901.1 AIG74918.1 AIG74918.1 AIG74939.1 AIG74939.1 AIG74998.1 AIG74998.1 bioA bioA hisC hisC AIG75185.1 AIG75185.1 AIG75228.1 AIG75228.1 AIG75323.1 AIG75323.1 AIG75324.1 AIG75324.1 AIG75361.1 AIG75361.1 argD argD kbl kbl AIG76048.1 AIG76048.1 AIG76059.1 AIG76059.1 AIG76107.1 AIG76107.1 AIG76120.1 AIG76120.1 AIG76541.1 AIG76541.1 AIG76542.1 AIG76542.1 rhbA rhbA AIG76751.1 AIG76751.1 gcvP2 gcvP2 AIG76992.1 AIG76992.1 AIG77161.1 AIG77161.1 sgaA sgaA tpl tpl AIG77656.1 AIG77656.1 csd csd rocD rocD AIG78206.1 AIG78206.1 AIG78411.1 AIG78411.1 AIG78846.1 AIG78846.1 AIG78958.1 AIG78958.1 AIG79035.1 AIG79035.1 AIG79117.1 AIG79117.1 dnrJ dnrJ AIG79226.1 AIG79226.1 AIG79383.1 AIG79383.1 gabT2 gabT2 AIG79709.1 AIG79709.1 AIG79912.1 AIG79912.1 aspC aspC AIG80158.1 AIG80158.1 hemL hemL dapC dapC AIG80292.1 AIG80292.1 AIG80388.1 AIG80388.1 glyA2 glyA2 AIG80748.1 AIG80748.1 AIG80928.1 AIG80928.1 AIG80932.1 AIG80932.1 AIG81227.1 AIG81227.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIG74060.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
AIG72996.1Hypothetical protein. (359 aa)
AIG73138.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
AIG73150.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
AIG73160.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (368 aa)
AIG73198.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (377 aa)
AIG73204.1Hypothetical protein; Is essential for optimal growth. (399 aa)
patPutative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (351 aa)
ectBDiaminobutyrate-2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa)
AIG73613.1Hypothetical protein. (383 aa)
AIG73658.1Pyridoxal-dependent decarboxylase. (465 aa)
metBCystathionine gamma-synthase. (397 aa)
metY1O-acetylhomoserine (thiol)-lyase. (433 aa)
gabT14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
AIG74189.1Methionine gamma-lyase. (372 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (393 aa)
dgdA2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
AIG74440.1Hypothetical protein. (459 aa)
iscSCysteine desulfurase. (398 aa)
AIG74654.1GntR family transcriptional regulator. (452 aa)
gcvP1Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (943 aa)
glyA1Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
AIG74734.1Hypothetical protein. (438 aa)
metY2O-acetylhomoserine (thiol)-lyase. (429 aa)
AIG74901.1Cysteine desulfurase. (393 aa)
AIG74918.1Hypothetical protein. (478 aa)
AIG74939.18-amino-7-oxononanoate synthase. (395 aa)
AIG74998.1class-V aminotransferase. (392 aa)
bioAAdenosylmethionine-8-amino-7- oxononanoateaminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (426 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa)
AIG75185.1Hypothetical protein. (447 aa)
AIG75228.1Hypothetical protein. (473 aa)
AIG75323.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (377 aa)
AIG75324.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (373 aa)
AIG75361.15-aminolevulinate synthase. (402 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (397 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (393 aa)
AIG76048.1Hypothetical protein. (486 aa)
AIG76059.1Adenosylmethionine-8-amino-7- oxononanoatetransaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
AIG76107.1Hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (382 aa)
AIG76120.1Class III aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (415 aa)
AIG76541.1class-V aminotransferase. (407 aa)
AIG76542.1GntR family transcriptional regulator. (445 aa)
rhbADiaminobutyrate-2-oxoglutarateaminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
AIG76751.1Hypothetical protein. (390 aa)
gcvP2Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (959 aa)
AIG76992.1Pyridoxal-dependent decarboxylase. (466 aa)
AIG77161.1GntR family transcriptional regulator. (392 aa)
sgaASerine-glyoxylate aminotransferase. (388 aa)
tplTyrosine phenol-lyase. (465 aa)
AIG77656.1Hypothetical protein. (457 aa)
csdPutative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (428 aa)
rocDOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
AIG78206.1Putative aminotransferase. (414 aa)
AIG78411.1Hypothetical protein. (341 aa)
AIG78846.1Class V aminotransferase. (454 aa)
AIG78958.1Kynureninase. (397 aa)
AIG79035.1Hypothetical protein. (339 aa)
AIG79117.1Hypothetical protein. (575 aa)
dnrJDaunorubicin biosynthesis sensory transduction protein DnrJ; Belongs to the DegT/DnrJ/EryC1 family. (369 aa)
AIG79226.1Hypothetical protein. (453 aa)
AIG79383.1GntR family transcriptional regulator. (449 aa)
gabT24-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
AIG79709.1Aminotransferase. (363 aa)
AIG79912.1L-alanine:N-amidino-3-keto-scyllo- inosamineaminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (411 aa)
aspCAspartate aminotransferase. (409 aa)
AIG80158.1Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (454 aa)
dapCPutative N-succinyldiaminopimelate aminotransferase DapC. (387 aa)
AIG80292.1GntR family transcriptional regulator. (484 aa)
AIG80388.1Hypothetical protein. (396 aa)
glyA2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
AIG80748.1Glutamate decarboxylase; Belongs to the group II decarboxylase family. (457 aa)
AIG80928.1Low-specificity L-threonine aldolase. (342 aa)
AIG80932.1Hypothetical protein. (395 aa)
AIG81227.1Hypothetical protein. (458 aa)
Your Current Organism:
Amycolatopsis japonica
NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.