(58 nodes) Butanoate metabolism network (Amycolatopsis japonica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIG73138.1	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
	acsA1	Acetyl-coenzyme A synthetase 1. (658 aa)
	paaJ	3-oxoadipyl-CoA/3-oxo-5, 6-dehydrosuberyl-CoAthiolase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	AIG74011.1	Hypothetical protein. (351 aa)
	fadA	Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
	AIG74018.1	Hypothetical protein. (723 aa)
	ilvX	Putative acetolactate synthase large subunit IlvX. (520 aa)
	gabT1	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
	gabD	Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Belongs to the aldehyde dehydrogenase family. (487 aa)
	dmlA	D-malate dehydrogenase [decarboxylating]. (353 aa)
	AIG74039.1	Ectoine utilization protein EutA. (246 aa)
	AIG74054.1	Hypothetical protein; Belongs to the TPP enzyme family. (543 aa)
	AIG74185.1	3-hydroxybutyryl-CoA dehydrogenase. (591 aa)
	AIG74298.1	enoyl-CoA hydratase/isomerase. (293 aa)
	ccr	Crotonyl-CoA reductase. (446 aa)
	AIG74435.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	ilvB1	Acetolactate synthase large subunit IlvB1. (624 aa)
	ilvH	Acetolactate synthase small subunit. (168 aa)
	catI	3-oxoadipate CoA-transferase subunit A. (269 aa)
	catJ	3-oxoadipate CoA-transferase subunit B. (251 aa)
	AIG74787.1	Hypothetical protein. (248 aa)
	AIG75455.1	Putative tartrate dehydrogenase/decarboxylase. (349 aa)
	AIG75635.1	enoyl-CoA hydratase. (257 aa)
	maiA	Maleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (265 aa)
	AIG76254.1	Hypothetical protein; Belongs to the TPP enzyme family. (579 aa)
	ech1	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase. (280 aa)
	hpdG	Acetaldehyde dehydrogenase 6; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (300 aa)
	AIG77097.1	3-oxoacyl-[acyl-carrier-protein] reductase. (265 aa)
	AIG77230.1	Hypothetical protein. (332 aa)
	gabD2a	Putative succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (524 aa)
	ilvB	Acetolactate synthase I/II/III large subunit; Belongs to the TPP enzyme family. (549 aa)
	AIG78077.1	Hypothetical protein. (266 aa)
	AIG78081.1	Hypothetical protein. (386 aa)
	atoB	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
	AIG78091.1	enoyl-CoA hydratase/carnithine racemase. (249 aa)
	AIG78092.1	Putative CoA-transferase subunit alpha. (286 aa)
	AIG78109.1	Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
	AIG78114.1	Hypothetical protein. (277 aa)
	AIG78168.1	Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	gabD2b	Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family. (537 aa)
	AIG78276.1	Hypothetical protein. (250 aa)
	AIG78277.1	Hypothetical protein. (638 aa)
	AIG78497.1	Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	gabT2	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	AIG79759.1	Hydroxymethylglutaryl-CoA lyase. (310 aa)
	AIG79862.1	Succinate dehydrogenase, cytochrome b556 subunit. (147 aa)
	sdhD	Succinate dehydrogenase hydrophobic membrane anchor protein. (139 aa)
	sdhA	Succinate dehydrogenase flavoprotein subunit. (584 aa)
	sdhB	Succinate dehydrogenase iron-sulfur protein. (256 aa)
	AIG80178.1	Hypothetical protein. (250 aa)
	korA	2-oxoglutarate oxidoreductase subunit KorA. (635 aa)
	korB	2-oxoglutarate oxidoreductase subunit KorB. (354 aa)
	AIG80348.1	Hypothetical protein; Belongs to the TPP enzyme family. (540 aa)
	bdh	3-hydroxybutyrate dehydrogenase. (252 aa)
	AIG80748.1	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (457 aa)
	AIG80811.1	3-hydroxybutyryl-CoA dehydrogenase. (507 aa)
	fadB2	3-hydroxybutyryl-CoA dehydrogenase. (286 aa)
	fadI	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)

Your Current Organism:

Amycolatopsis japonica

NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIG73138.1	AIG80748.1	AJAP_01005	AJAP_39845	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.928
AIG73138.1	gabD	AJAP_01005	AJAP_05570	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Belongs to the aldehyde dehydrogenase family.	0.925
AIG73138.1	gabD2a	AJAP_01005	AJAP_22425	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Putative succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family.	0.922
AIG73138.1	gabD2b	AJAP_01005	AJAP_26640	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family.	0.922
AIG73138.1	gabT1	AJAP_01005	AJAP_05565	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.918
AIG73138.1	gabT2	AJAP_01005	AJAP_33625	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.915
AIG74011.1	AIG74018.1	AJAP_05455	AJAP_05490	Hypothetical protein.	Hypothetical protein.	0.920
AIG74018.1	AIG74011.1	AJAP_05490	AJAP_05455	Hypothetical protein.	Hypothetical protein.	0.920
AIG74018.1	AIG74185.1	AJAP_05490	AJAP_06335	Hypothetical protein.	3-hydroxybutyryl-CoA dehydrogenase.	0.925
AIG74018.1	AIG74298.1	AJAP_05490	AJAP_06905	Hypothetical protein.	enoyl-CoA hydratase/isomerase.	0.932
AIG74018.1	AIG74435.1	AJAP_05490	AJAP_07625	Hypothetical protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.994
AIG74018.1	AIG75635.1	AJAP_05490	AJAP_13770	Hypothetical protein.	enoyl-CoA hydratase.	0.926
AIG74018.1	AIG77230.1	AJAP_05490	AJAP_21860	Hypothetical protein.	Hypothetical protein.	0.935
AIG74018.1	AIG78077.1	AJAP_05490	AJAP_26150	Hypothetical protein.	Hypothetical protein.	0.922
AIG74018.1	AIG78081.1	AJAP_05490	AJAP_26170	Hypothetical protein.	Hypothetical protein.	0.994
AIG74018.1	AIG78091.1	AJAP_05490	AJAP_26220	Hypothetical protein.	enoyl-CoA hydratase/carnithine racemase.	0.922
AIG74018.1	AIG78109.1	AJAP_05490	AJAP_26310	Hypothetical protein.	Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.994
AIG74018.1	AIG78114.1	AJAP_05490	AJAP_26335	Hypothetical protein.	Hypothetical protein.	0.922
AIG74018.1	AIG78168.1	AJAP_05490	AJAP_26605	Hypothetical protein.	Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.937
AIG74018.1	AIG78497.1	AJAP_05490	AJAP_28295	Hypothetical protein.	Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.925