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fimU fimU pilV pilV pilW pilW pilX pilX pilY1 pilY1 pilE pilE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fimUType 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (168 aa)
pilVType 4 fimbrial biogenesis protein PilV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (185 aa)
pilWType 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (274 aa)
pilXType 4 fimbrial biogenesis protein PilX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (195 aa)
pilY1Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity). (1161 aa)
pilEType 4 fimbrial biogenesis protein PilE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (141 aa)
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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