6 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dctA	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane. (436 aa)
	dctB	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity). (612 aa)
	dctD	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. (462 aa)
	mifR	MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (447 aa)
	mifS	MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (588 aa)
	PA5530	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (435 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA5530	dctA	PA5530	PA1183	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	0.743
PA5530	dctB	PA5530	PA5165	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	0.587
PA5530	dctD	PA5530	PA5166	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	0.700
PA5530	mifR	PA5530	PA5511	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.880
PA5530	mifS	PA5530	PA5512	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.428
dctA	PA5530	PA1183	PA5530	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.743
dctA	dctB	PA1183	PA5165	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	0.840
dctA	dctD	PA1183	PA5166	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	0.869
dctA	mifR	PA1183	PA5511	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.433
dctA	mifS	PA1183	PA5512	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.534
dctB	PA5530	PA5165	PA5530	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.587
dctB	dctA	PA5165	PA1183	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	0.840
dctB	dctD	PA5165	PA5166	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	0.999
dctB	mifR	PA5165	PA5511	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.992
dctB	mifS	PA5165	PA5512	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.937
dctD	PA5530	PA5166	PA5530	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	Probable MFS dicarboxylate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.700
dctD	dctA	PA5166	PA1183	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.	0.869
dctD	dctB	PA5166	PA5165	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity).	0.999
dctD	mifR	PA5166	PA5511	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.910
dctD	mifS	PA5166	PA5512	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.	MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.990