3 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cyaA	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). (950 aa)
	cyaB	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (463 aa)
	exoY	Adenylate cyclase ExoY; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (378 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cyaA	cyaB	PA5272	PA3217	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein).	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.989
cyaA	exoY	PA5272	PA2191	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein).	Adenylate cyclase ExoY; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.885
cyaB	cyaA	PA3217	PA5272	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.989
exoY	cyaA	PA2191	PA5272	Adenylate cyclase ExoY; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.885