STRINGSTRING
wspB wspB wspA wspA PA3714 PA3714 suhB suhB narX narX narL narL fecA fecA rocS1 rocS1 rocR rocR rocA1 rocA1 ladS ladS PA4032 PA4032 PA4036 PA4036 PA4080 PA4080 bfmR bfmR bfmS bfmS PA4112 PA4112 bphP bphP bfiR bfiR bfiS bfiS PA4290 PA4290 pprA pprA pprB pprB pctC pctC pctA pctA pctB pctB PA4380 PA4380 PA4381 PA4381 PA4396 PA4396 PA4398 PA4398 roxR roxR roxS roxS PA4520 PA4520 pilS pilS pilR pilR PA4608 PA4608 PA4633 PA4633 cbrA cbrA cbrB cbrB pmrA pmrA pmrB pmrB PA4781 PA4781 PA4806 PA4806 PA4843 PA4843 ctpL ctpL retS retS irlR irlR PA4886 PA4886 PA4915 PA4915 fimX fimX aruS aruS aruR aruR PA5072 PA5072 ntrB ntrB ntrC ntrC PA5134 PA5134 dctB dctB dctD dctD amgS amgS amgR amgR algR algR algZ algZ phoB phoB phoR phoR PA5364 PA5364 algB algB PA5484 PA5484 mifR mifR mifS mifS wspD wspD wspE wspE wspF wspF wspR wspR PA3649 PA3649 erdR erdR PA3599 PA3599 rhlI rhlI PA3462 PA3462 hasR hasR PA3349 PA3349 PA3346 PA3346 PA3345 PA3345 PA3271 PA3271 prc prc cyaB cyaB PA3206 PA3206 PA3204 PA3204 gltR gltR PA3191 PA3191 PA3078 PA3078 PA3077 PA3077 PA3045 PA3045 PA3044 PA3044 PA2920 PA2920 PA2899 PA2899 PA2882 PA2882 PA2881 PA2881 PA2867 PA2867 PA2824 PA2824 copS copS copR copR PA2798 PA2798 PA2788 PA2788 pfeS pfeS pfeR pfeR PA2657 PA2657 PA2656 PA2656 PA2654 PA2654 PA2652 PA2652 PA2591 PA2591 gacA gacA PA2583 PA2583 PA2573 PA2573 PA2572 PA2572 PA2571 PA2571 ctpH ctpH PA2524 PA2524 PA2523 PA2523 PA2480 PA2480 PA2479 PA2479 foxA foxA PA2376 PA2376 PA2177 PA2177 PA2137 PA2137 ercS-2 ercS-2 eraR eraR eraS eraS erbR erbR ercS ercS PA1930 PA1930 fimL fimL parR parR parS parS PA1785 PA1785 PA1646 PA1646 kdpE kdpE kdpD kdpD PA1611 PA1611 PA1608 PA1608 aer aer PA1510 PA1510 PA1484 PA1484 PA1464 PA1464 PA1463 PA1463 cheB1 cheB1 PA1458 PA1458 cheY cheY PA1438 PA1438 PA1437 PA1437 PA1433 PA1433 lasI lasI bdlA bdlA PA1397 PA1397 PA1396 PA1396 PA1336 PA1336 PA1335 PA1335 PA1302 PA1302 PA1251 PA1251 PA1243 PA1243 phoQ phoQ phoP phoP PA1158 PA1158 PA1157 PA1157 tpbB tpbB fleR fleR fleS fleS PA0991 PA0991 PA0930 PA0930 PA0929 PA0929 gacS gacS PA0847 PA0847 mucD mucD PA0757 PA0757 PA0756 PA0756 PA0601 PA0601 PA0600 PA0600 fiuA fiuA creC creC creB creB chpC chpC chpB chpB chpA chpA pilJ pilJ pilI pilI pilH pilH pilG pilG PA0267 PA0267 cttP cttP PA0179 PA0179 PA0178 PA0178 PA0177 PA0177 aer2 aer2 cheB2 cheB2 PA0172 PA0172 PA0151 PA0151 PA0034 PA0034 PA0033 PA0033
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wspBHypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (171 aa)
wspAProbable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (542 aa)
PA3714Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (213 aa)
suhBExtragenic suppressor protein SuhB; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the inositol monophosphatase superfamily. (271 aa)
narXTwo-component sensor NarX; Product name confidence: Class 2 (High similarity to functionally studied protein). (622 aa)
narLTwo-component response regulator NarL; Product name confidence: Class 2 (High similarity to functionally studied protein). (219 aa)
fecAFe(III) dicitrate transport protein FecA; Product name confidence: Class 2 (High similarity to functionally studied protein). (784 aa)
rocS1Probable two-component sensor; Class 1: Function experimentally demonstrated in P. aeruginosa. (1212 aa)
rocRRocR; Class 1: Function experimentally demonstrated in P. aeruginosa. (392 aa)
rocA1Two-component response regulator RocA1; Class 1: Function experimentally demonstrated in P. aeruginosa. (209 aa)
ladSLost Adherence Sensor, LadS; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (795 aa)
PA4032Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (238 aa)
PA4036Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (766 aa)
PA4080Probable response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (214 aa)
bfmRBfmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (246 aa)
bfmSBfmS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (434 aa)
PA4112Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (1417 aa)
bphPBacterial phytochrome, BphP; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region; In the N-terminal section; belongs to the phytochrome family. (728 aa)
bfiRBfiR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (214 aa)
bfiSBfiS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (758 aa)
PA4290Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (538 aa)
pprATwo-component sensor PprA; Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae. Modulates also quorum-sensing signal production acting on both negative and positive modulators. Functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to PprB. (922 aa)
pprBTwo-component response regulator, PprB; Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae. Modulates also quorum-sensing signal production acting on both negative and positive modulators. Functions as a transcription regulator by direct binding to promoter regions. Negatively regulates its own transcription. (275 aa)
pctCChemotactic transducer PctC; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-His, L-Pro and GABA. Also involved in repellent responses to trichloroethylene (TCE), chloroform and methylthiocyanate. (632 aa)
pctAChemotactic transducer PctA; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Major receptor that responds to all naturally occurring L- amino acids, except L-Gln and L-Asp. Also involved in repellent responses to trichloroethylene (TCE), chloroform and methylthiocyanate. (629 aa)
pctBChemotactic transducer PctB; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-Arg, L-Gln, L-Ala, L-Glu, L-Lys, L-Met and L-Tyr. Also involved in repellent responses to trichloroethylene (TCE), chloroform and methylthiocyanate. (629 aa)
PA4380Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (426 aa)
PA4381Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (227 aa)
PA4396Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (366 aa)
PA4398Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (698 aa)
roxRRoxR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (186 aa)
roxSRoxS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (422 aa)
PA4520Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (673 aa)
pilSTwo-component sensor PilS; Member of the two-component regulatory system PilS/PilR involved in the regulation of the expression of type 4 fimbriae. PilS may function as a membrane-associated protein kinase that phosphorylates PilR in response to environmental signals. (530 aa)
pilRTwo-component response regulator PilR; Member of the two-component regulatory system PilS/PilR that regulates the expression of type 4 fimbriae. When activated by PilS it acts in conjunction with sigma-54 as a transcriptional activator. (445 aa)
PA4608Hypothetical protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. (125 aa)
PA4633Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (712 aa)
cbrATwo-component sensor CbrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (983 aa)
cbrBTwo-component response regulator CbrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (478 aa)
pmrAPmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (221 aa)
pmrBPmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (477 aa)
PA4781Cyclic di-GMP phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP. Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture. May act preferentially as a pGpG binding protein. (393 aa)
PA4806Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (227 aa)
PA4843Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (542 aa)
ctpLProbable chemotaxis transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Chemoreceptor for inorganic phosphate, which is required for taxis at low concentrations of phosphate. Is also responsible for the positive chemotaxis toward 4-chloroaniline (4CA) and catechol. Does not recognize inorganic phosphate directly, but via a complex between the periplasmic protei [...] (657 aa)
retSRetS (Regulator of Exopolysaccharide and Type III Secretion); Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (942 aa)
irlRTwo-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein). (229 aa)
PA4886Probable two-component sensor; Member of a two-component regulatory system. (463 aa)
PA4915Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (541 aa)
fimXFimX; Class 1: Function experimentally demonstrated in P. aeruginosa. (691 aa)
aruSProbable two-component sensor; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Probably functions as a sensor kinase that phosphorylates AruR. (998 aa)
aruRProbable two-component response regulator; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Regulates transcription of aruH and aruI. (244 aa)
PA5072Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (647 aa)
ntrBTwo-component sensor NtrB; Product name confidence: Class 2 (High similarity to functionally studied protein). (358 aa)
ntrCTwo-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (476 aa)
PA5134Probable carboxyl-terminal protease; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the peptidase S41A family. (436 aa)
dctBProbable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity). (612 aa)
dctDProbable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. (462 aa)
amgSAmgS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (439 aa)
amgRAmgR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (247 aa)
algRAlginate biosynthesis regulatory protein AlgR; Positive regulator of the algD gene, which codes for a GDP- mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway. (248 aa)
algZAlginate biosynthesis protein AlgZ/FimS; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (358 aa)
phoBTwo-component response regulator PhoB; This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. (229 aa)
phoRTwo-component sensor PhoR; Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. (443 aa)
PA5364Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (300 aa)
algBTwo-component response regulator AlgB; Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD. (449 aa)
PA5484Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (595 aa)
mifRMifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (447 aa)
mifSMifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (588 aa)
wspDHypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (229 aa)
wspEProbable chemotaxis sensor/effector fusion protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (769 aa)
wspFProbable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (335 aa)
wspRProbable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (347 aa)
PA3649Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the peptidase M50B family. (450 aa)
erdRResponse regulator ErdR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (217 aa)
PA3599Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (261 aa)
rhlIAutoinducer synthesis protein RhlI; Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to RhlR and thus acts in elastase biosynthesis regulation. (201 aa)
PA3462Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (919 aa)
hasRHeme uptake outer membrane receptor HasR precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). (891 aa)
PA3349Probable chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (310 aa)
PA3346Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (571 aa)
PA3345Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (116 aa)
PA3271Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (1159 aa)
prcPeriplasmic tail-specific protease; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S41A family. (698 aa)
cyaBCyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (463 aa)
PA3206Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (445 aa)
PA3204Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (225 aa)
gltRTwo-component response regulator GltR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (242 aa)
PA3191Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (473 aa)
PA3078Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (431 aa)
PA3077Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa)
PA3045Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (207 aa)
PA3044Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (741 aa)
PA2920Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (545 aa)
PA2899Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (212 aa)
PA2882Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (371 aa)
PA2881Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (303 aa)
PA2867Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (490 aa)
PA2824Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (786 aa)
copSTwo-component sensor, CopS; Member of a two-component regulatory system. (443 aa)
copRTwo-component response regulator, CopR; Class 1: Function experimentally demonstrated in P. aeruginosa. (226 aa)
PA2798Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (394 aa)
PA2788Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (531 aa)
pfeSTwo-component sensor PfeS; Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation. (446 aa)
pfeRTwo-component response regulator PfeR; Member of the two-component regulatory system PfeR/PfeS. Activates expression of the ferric enterobactin receptor. (305 aa)
PA2657Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa)
PA2656Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (445 aa)
PA2654Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (714 aa)
PA2652Probable chemotaxis transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Chemoreceptor for malate. (561 aa)
PA2591Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (268 aa)
gacAResponse regulator GacA; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase. (214 aa)
PA2583Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (992 aa)
PA2573Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (535 aa)
PA2572Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (447 aa)
PA2571Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (470 aa)
ctpHProbable chemotaxis transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Chemoreceptor for inorganic phosphate, which is required for taxis at high concentrations of phosphate. Recognizes inorganic phosphate directly. Can also bind to other components that have a pyrophosphate group, including ATP and ADP. (568 aa)
PA2524Probable two-component sensor; Member of a two-component regulatory system. (472 aa)
PA2523Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (224 aa)
PA2480Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (440 aa)
PA2479Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (226 aa)
foxAFerrioxamine receptor FoxA; Class 1: Function experimentally demonstrated in P. aeruginosa. (820 aa)
PA2376Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (213 aa)
PA2177Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (699 aa)
PA2137Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (178 aa)
ercS-2ErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (564 aa)
eraRResponse regulator EraR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (225 aa)
eraSSensor kinase, EraS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (216 aa)
erbRResponse regulator ErbR; Positive activator for glycerol metabolism. (221 aa)
ercSErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (881 aa)
PA1930Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (431 aa)
fimLHypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (562 aa)
parRTwo-component response regulator, ParR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (235 aa)
parSTwo-component sensor, ParS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (428 aa)
PA1785Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (192 aa)
PA1646Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (652 aa)
kdpETwo-component response regulator KdpE; Product name confidence: Class 2 (High similarity to functionally studied protein). (230 aa)
kdpDTwo-component sensor KdpD; Product name confidence: Class 2 (High similarity to functionally studied protein). (885 aa)
PA1611Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (651 aa)
PA1608Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (541 aa)
aerAerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein). (521 aa)
PA1510Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (569 aa)
PA1484Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (268 aa)
PA1464Probable purine-binding chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (159 aa)
PA1463Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (296 aa)
cheB1Probable methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. (368 aa)
PA1458Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (753 aa)
cheYTwo-component response regulator CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY is likely to be involved in changing the direction of flagellar rotation. (124 aa)
PA1438Probable two-component sensor; Member of a two-component regulatory system. (481 aa)
PA1437Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (229 aa)
PA1433Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (650 aa)
lasIAutoinducer synthesis protein LasI; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation. (201 aa)
bdlABdlA; Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface. (417 aa)
PA1397Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (210 aa)
PA1396Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (540 aa)
PA1336Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (633 aa)
PA1335Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (425 aa)
PA1302Probable heme utilization protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (851 aa)
PA1251Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (541 aa)
PA1243Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (858 aa)
phoQTwo-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (448 aa)
phoPTwo-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (225 aa)
PA1158Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (452 aa)
PA1157Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (236 aa)
tpbBDiguanylate cyclase TpbB; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (435 aa)
fleRTwo-component response regulator; Plays a role in the regulation of both flagellar synthesis and adhesion to mucin. (473 aa)
fleSTwo-component sensor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (402 aa)
PA0991Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (125 aa)
PA0930Two-component sensor; Product name confidence: Class 2 (High similarity to functionally studied protein). (445 aa)
PA0929Two-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein). (239 aa)
gacSSensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). (925 aa)
PA0847Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (735 aa)
mucDSerine protease MucD precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase S1C family. (474 aa)
PA0757Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (460 aa)
PA0756Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa)
PA0601Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (210 aa)
PA0600Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (797 aa)
fiuAFerrichrome receptor FiuA; Class 1: Function experimentally demonstrated in P. aeruginosa. (802 aa)
creCTwo-component sensor CreC; Product name confidence: Class 2 (High similarity to functionally studied protein). (474 aa)
creBTwo-component response regulator CreB; Product name confidence: Class 2 (High similarity to functionally studied protein). (229 aa)
chpCProbable chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (168 aa)
chpBProbable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (343 aa)
chpAComponent of chemotactic signal transduction system; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (2472 aa)
pilJTwitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (682 aa)
pilITwitching motility protein PilI; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (178 aa)
pilHTwitching motility protein PilH; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (121 aa)
pilGTwitching motility protein PilG; Is involved in pilus biosynthesis and twitching motility. May act as a single-domain response regulator whose function may be to receive a certain environmental signal(s) and then transduce that signal to the pilus assembly machinery via specific protein-protein interactions. (135 aa)
PA0267Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (399 aa)
cttPChemotactic transducer for trichloroethylene [positive chemotaxis], CttP; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (390 aa)
PA0179Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (121 aa)
PA0178Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (639 aa)
PA0177Probable purine-binding chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (161 aa)
aer2Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (679 aa)
cheB2Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. (349 aa)
PA0172Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (663 aa)
PA0151Probable TonB-dependent receptor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (795 aa)
PA0034Probable two-component response regulator; Probable transcriptional regulator. (207 aa)
PA0033Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (121 aa)
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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