Your Input: | |
| | gbdR | GbdR; Class 1: Function experimentally demonstrated in P. aeruginosa. (367 aa) |
| | trpI | Transcriptional regulator TrpI; Activates the expression of the trpBA genes, which encode the two tryptophan synthase subunits, and represses initiation at its own promoter. Acts by binding to two adjacent sites in the intergenic region. In the absence of the inducer indoleglycerol phosphate (InGP), TrpI binds to site I. In the presence of InGP, TrpI binds to site I and site II. Binding to site II is site I dependent. InGP strongly stimulates binding to site II and is required for maximal activation of trpBA. Belongs to the LysR transcriptional regulatory family. (295 aa) |
| | ppkA | Serine/threonine protein kinase PpkA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (1032 aa) |
| | bauR | Probable transcriptional regulator; Involved in the degradation of beta-alanine. BauR activates the transcription of the bauABCD operon; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | pcaQ | Transcriptional regulator PcaQ; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the LysR transcriptional regulatory family. (275 aa) |
| | pcaR | Transcriptional regulator PcaR; Product name confidence: Class 2 (High similarity to functionally studied protein). (279 aa) |
| | PA0267 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (399 aa) |
| | chpD | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (264 aa) |
| | creB | Two-component response regulator CreB; Product name confidence: Class 2 (High similarity to functionally studied protein). (229 aa) |
| | dnr | Transcriptional regulator Dnr; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (227 aa) |
| | PA0564 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (303 aa) |
| | prtN | Transcriptional regulator PrtN; Activates pyocin genes, probably by binding to the sequences conserved in their 5' non-coding regions (P box). (104 aa) |
| | ptrB | Repressor, PtrB; Class 1: Function experimentally demonstrated in P. aeruginosa. (66 aa) |
| | vfr | Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. (214 aa) |
| | toxR | Transcriptional regulator ToxR; Positive regulation of toxA gene transcription. (259 aa) |
| | PA0756 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa) |
| | algU | Sigma factor AlgU; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis. (193 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | pruR | Proline utilization regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (250 aa) |
| | PA0791 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (262 aa) |
| | PA0864 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (262 aa) |
| | argR | Transcriptional regulator ArgR; ArgR could be a transcriptional activator of the dauBAR operon in response to the presence of L-Arg. (329 aa) |
| | rsmA | RsmA, regulator of secondary metabolites; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably [...] (61 aa) |
| | PA0907 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (176 aa) |
| | gacS | Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). (925 aa) |
| | PA0929 | Two-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein). (239 aa) |
| | fleQ | Transcriptional regulator FleQ; AAA+ ATPase enhancer-binding protein that acts as a transcription regulator and plays a role in the modulation of mucin adhesion and flagellar gene expression. In addition to flagella genes, regulates also expression of biofilm-related genes. Functions as a transcriptional repressor in the absence of c-di-GMP and as an activator when c-di-GMP is present. (490 aa) |
| | fleR | Two-component response regulator; Plays a role in the regulation of both flagellar synthesis and adhesion to mucin. (473 aa) |
| | PA1109 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (259 aa) |
| | PA1157 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (236 aa) |
| | phoP | Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (225 aa) |
| | PA1195 | Hypothetical protein; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)- monomethyl-L-arginine (MMA). (254 aa) |
| | PA1229 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (268 aa) |
| | PA1235 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (260 aa) |
| | aprA | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. (479 aa) |
| | PA1261 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (224 aa) |
| | PA1396 | Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (540 aa) |
| | lasR | Transcriptional regulator LasR; Transcriptional activator of elastase structural gene (LasB). Binds to the PAI autoinducer; Belongs to the autoinducer-regulated transcriptional regulatory protein family. (239 aa) |
| | rsaL | Regulatory protein RsaL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (80 aa) |
| | PA1437 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (229 aa) |
| | fliA | Sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes (By similarity). Required for the flagellin gene (fliC) expression; Belongs to the sigma-70 factor family. FliA subfamily. (247 aa) |
| | cheY | Two-component response regulator CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY is likely to be involved in changing the direction of flagellar rotation. (124 aa) |
| | PA1484 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (268 aa) |
| | PA1599 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (260 aa) |
| | PA1619 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (274 aa) |
| | kdpE | Two-component response regulator KdpE; Product name confidence: Class 2 (High similarity to functionally studied protein). (230 aa) |
| | exsC | ExsC, exoenzyme S synthesis protein C precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (145 aa) |
| | exsA | Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level. (278 aa) |
| | cysB | Transcriptional regulator CysB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the LysR transcriptional regulatory family. (324 aa) |
| | sigX | ECF sigma factor SigX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sigma-70 factor family. ECF subfamily. (165 aa) |
| | parR | Two-component response regulator, ParR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (235 aa) |
| | qscR | Quorum-sensing control repressor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (237 aa) |
| | eraS | Sensor kinase, EraS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (216 aa) |
| | eraR | Response regulator EraR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (225 aa) |
| | dhcR | DhcR, transcriptional regulator; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the LysR transcriptional regulatory family. (306 aa) |
| | PA2047 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (329 aa) |
| | PA2206 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family. (315 aa) |
| | vqsM | AraC-type transcriptional regulator VqsM; Transcriptional regulator involved in both the repression (at least 99 genes, such as mexR and algU) and in the activation (at least 203 genes, such as mvfR, rsaL, vqsR and rpoS) of regulatory or putative regulatory proteins which are implicated in quorum sensing, virulence and multidrug resistance. (325 aa) |
| | ptxR | Transcriptional regulator PtxR; Transcriptional activator of the toxA (exotoxin) and regA genes. (312 aa) |
| | PA2281 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (284 aa) |
| | mtlR | Transcriptional regulator MtlR; Product name confidence: Class 2 (High similarity to functionally studied protein). (301 aa) |
| | pvdS | Sigma factor PvdS; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | PA2449 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (511 aa) |
| | PA2479 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (226 aa) |
| | PA2488 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (254 aa) |
| | mexT | Transcriptional regulator MexT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (347 aa) |
| | PA2511 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (333 aa) |
| | xylS | Transcriptional regulator XylS; Product name confidence: Class 2 (High similarity to functionally studied protein). (318 aa) |
| | PA2523 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (224 aa) |
| | gacA | Response regulator GacA; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase. (214 aa) |
| | PA2591 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (268 aa) |
| | PA2657 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa) |
| | pfeR | Two-component response regulator PfeR; Member of the two-component regulatory system PfeR/PfeS. Activates expression of the ferric enterobactin receptor. (305 aa) |
| | PA2696 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (297 aa) |
| | himA | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. (100 aa) |
| | PA2780 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (114 aa) |
| | PA2797 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (160 aa) |
| | PA2798 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (394 aa) |
| | copR | Two-component response regulator, CopR; Class 1: Function experimentally demonstrated in P. aeruginosa. (226 aa) |
| | ospR | OspR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (163 aa) |
| | psrA | Transcriptional regulator PsrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (233 aa) |
| | PA3077 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (223 aa) |
| | PA3133 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (180 aa) |
| | gltR | Two-component response regulator GltR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (242 aa) |
| | PA3204 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (225 aa) |
| | PA3345 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (116 aa) |
| | pmrA | PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (221 aa) |
| | fur | Ferric uptake regulation protein; Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon. Involved in exotoxin A regulation, siderophore regulation and manganese susceptibility. (134 aa) |
| | cbrB | Two-component response regulator CbrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (478 aa) |
| | cbrA | Two-component sensor CbrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (983 aa) |
| | dksA | Suppressor protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. (148 aa) |
| | ptsN | Nitrogen regulatory IIA protein; Seems to have a role in regulating nitrogen assimilation. (154 aa) |
| | rpoN | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (497 aa) |
| | PA4436 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (299 aa) |
| | sspB | Stringent starvation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). (135 aa) |
| | PA4381 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (227 aa) |
| | PA4332 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (487 aa) |
| | mvaT | Transcriptional regulator MvaT, P16 subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (124 aa) |
| | pprB | Two-component response regulator, PprB; Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae. Modulates also quorum-sensing signal production acting on both negative and positive modulators. Functions as a transcription regulator by direct binding to promoter regions. Negatively regulates its own transcription. (275 aa) |
| | rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | pchR | Transcriptional regulator PchR; Positive activator of the genes for pyochelin and ferripyochelin receptors. (296 aa) |
| | bfiS | BfiS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (758 aa) |
| | bphP | Bacterial phytochrome, BphP; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region; In the N-terminal section; belongs to the phytochrome family. (728 aa) |
| | ampR | Transcriptional regulator AmpR; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. (296 aa) |
| | PA4108 | Cyclic di-GMP phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP. Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture. (414 aa) |
| | bfmR | BfmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (246 aa) |
| | PA4094 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (319 aa) |
| | PA4070 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (316 aa) |
| | PA4032 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (238 aa) |
| | rocA1 | Two-component response regulator RocA1; Class 1: Function experimentally demonstrated in P. aeruginosa. (209 aa) |
| | PA3927 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (262 aa) |
| | PA3898 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (293 aa) |
| | holC | DNA polymerase III, chi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity). (142 aa) |
| | PA3830 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (270 aa) |
| | PA3757 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (247 aa) |
| | armR | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (53 aa) |
| | PA3689 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (156 aa) |
| | rpoS | Sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (334 aa) |
| | PA3599 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (261 aa) |
| | mmsR | Transcriptional regulator MmsR; Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes. (307 aa) |
| | rhlR | Transcriptional regulator RhlR; Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). (241 aa) |
| | PA3423 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (247 aa) |
| | nosR | Regulatory protein NosR; Transcriptional activator of the nitrous-oxide reductase gene NosZ. (715 aa) |
| | amrZ | Alginate and motility regulator Z; Functions as both a transcriptional activator and repressor of multiple genes encoding virulence factors as well as genes involved in environmental adaptation. Plays a role in alginate production via the activation of AlgD which is the first gene in the alginate biosynthetic operon. Regulates also the transcription of genes responsible for type IV pili localization and twitching motility. Mediates transition of P.aeruginosa biofilm infections from colonizing to chronic biofilms through repression of the psl operon. Represses also its own transcription [...] (108 aa) |
| | cueR | CueR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (132 aa) |
| | PA4781 | Cyclic di-GMP phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP. Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture. May act preferentially as a pGpG binding protein. (393 aa) |
| | PA4806 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (227 aa) |
| | PA4843 | Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (542 aa) |
| | PA4857 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (197 aa) |
| | PA4870 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (88 aa) |
| | PA4878 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (270 aa) |
| | irlR | Two-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein). (229 aa) |
| | aruR | Probable two-component response regulator; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Regulates transcription of aruH and aruI. (244 aa) |
| | hslU | Heat shock protein HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (447 aa) |
| | PA5085 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family. (318 aa) |
| | typA | Regulatory protein TypA; Product name confidence: Class 2 (High similarity to functionally studied protein). (605 aa) |
| | dctB | Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity). (612 aa) |
| | dctD | Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. (462 aa) |
| | amgR | AmgR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (247 aa) |
| | algQ | Alginate regulatory protein AlgQ; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process. (160 aa) |
| | algR | Alginate biosynthesis regulatory protein AlgR; Positive regulator of the algD gene, which codes for a GDP- mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway. (248 aa) |
| | algZ | Alginate biosynthesis protein AlgZ/FimS; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (358 aa) |
| | PA5324 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (356 aa) |
| | PA5342 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (266 aa) |
| | oxyR | OxyR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the LysR transcriptional regulatory family. (310 aa) |
| | phoB | Two-component response regulator PhoB; This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. (229 aa) |
| | cdhR | CdhR, transcriptional regulator; Induces the transcription of the PA5384-PA5388 operon in response to carnitine. This operon is involved in the degradation of L- carnitine, and allows P.aeruginosa to grow on L-carnitine as the sole source of carbon and nitrogen. (336 aa) |
| | PA5471 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (379 aa) |
| | algB | Two-component response regulator AlgB; Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD. (449 aa) |
| | mifR | MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (447 aa) |
| | glmR | GlmR transcriptional regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (257 aa) |
| | spoOJ | Chromosome partitioning protein Spo0J; Product name confidence: Class 2 (High similarity to functionally studied protein). (290 aa) |
| | PA3347 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (101 aa) |
