15 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PA4843	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (542 aa)
	PA5487	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (671 aa)
	PA4857	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (197 aa)
	PA4332	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (487 aa)
	wspR	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (347 aa)
	amrZ	Alginate and motility regulator Z; Functions as both a transcriptional activator and repressor of multiple genes encoding virulence factors as well as genes involved in environmental adaptation. Plays a role in alginate production via the activation of AlgD which is the first gene in the alginate biosynthetic operon. Regulates also the transcription of genes responsible for type IV pili localization and twitching motility. Mediates transition of P.aeruginosa biofilm infections from colonizing to chronic biofilms through repression of the psl operon. Represses also its own transcription [...] (108 aa)
	PA3343	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (389 aa)
	PA3177	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (307 aa)
	PA2870	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (525 aa)
	PA1851	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (401 aa)
	PA1107	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (398 aa)
	fleQ	Transcriptional regulator FleQ; AAA+ ATPase enhancer-binding protein that acts as a transcription regulator and plays a role in the modulation of mucin adhesion and flagellar gene expression. In addition to flagella genes, regulates also expression of biofilm-related genes. Functions as a transcriptional repressor in the absence of c-di-GMP and as an activator when c-di-GMP is present. (490 aa)
	algU	Sigma factor AlgU; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis. (193 aa)
	PA0290	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (323 aa)
	PA0169	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (235 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA0290	PA1107	PA0290	PA1107	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.522
PA0290	PA1851	PA0290	PA1851	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.644
PA0290	PA2870	PA0290	PA2870	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.508
PA0290	PA3177	PA0290	PA3177	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.522
PA0290	PA3343	PA0290	PA3343	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.587
PA0290	PA4332	PA0290	PA4332	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.440
PA0290	PA4843	PA0290	PA4843	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.520
PA0290	wspR	PA0290	PA3702	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.496
PA1107	PA0290	PA1107	PA0290	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.522
PA1107	PA1851	PA1107	PA1851	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.429
PA1107	PA2870	PA1107	PA2870	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.533
PA1107	PA3177	PA1107	PA3177	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.502
PA1107	PA3343	PA1107	PA3343	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.588
PA1107	PA4332	PA1107	PA4332	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.481
PA1107	PA4843	PA1107	PA4843	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.489
PA1107	wspR	PA1107	PA3702	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.514
PA1851	PA0290	PA1851	PA0290	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.644
PA1851	PA1107	PA1851	PA1107	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.429
PA1851	PA2870	PA1851	PA2870	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.552
PA1851	PA3177	PA1851	PA3177	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.441