STRINGSTRING
kdpD kdpD ercS ercS eraS eraS ercS-2 ercS-2 PA2177 PA2177 PA2480 PA2480 PA2524 PA2524 PA2571 PA2571 PA2583 PA2583 PA2656 PA2656 rocS1 rocS1 narX narX wspE wspE PA3462 PA3462 PA3346 PA3346 PA3271 PA3271 PA3206 PA3206 PA3191 PA3191 PA3078 PA3078 PA3044 PA3044 PA2882 PA2882 PA2824 PA2824 pfeS pfeS mifS mifS PA5484 PA5484 phoR phoR amgS amgS dctB dctB ntrB ntrB aruS aruS copS copS parE parE mutL mutL PA4886 PA4886 retS retS pmrB pmrB cbrA cbrA pilS pilS roxS roxS PA4398 PA4398 PA4380 PA4380 pprA pprA bfiS bfiS bphP bphP PA4112 PA4112 bfmS bfmS PA4036 PA4036 ladS ladS PA1396 PA1396 PA1438 PA1438 PA1458 PA1458 htpG htpG PA1611 PA1611 parS parS gyrB gyrB PA0178 PA0178 chpA chpA creC creC PA0600 PA0600 PA0757 PA0757 gacS gacS PA0930 PA0930 PA1068 PA1068 fleS fleS PA1158 PA1158 phoQ phoQ PA1243 PA1243 PA1336 PA1336
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdpDTwo-component sensor KdpD; Product name confidence: Class 2 (High similarity to functionally studied protein). (885 aa)
ercSErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (881 aa)
eraSSensor kinase, EraS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (216 aa)
ercS-2ErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (564 aa)
PA2177Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (699 aa)
PA2480Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (440 aa)
PA2524Probable two-component sensor; Member of a two-component regulatory system. (472 aa)
PA2571Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (470 aa)
PA2583Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (992 aa)
PA2656Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (445 aa)
rocS1Probable two-component sensor; Class 1: Function experimentally demonstrated in P. aeruginosa. (1212 aa)
narXTwo-component sensor NarX; Product name confidence: Class 2 (High similarity to functionally studied protein). (622 aa)
wspEProbable chemotaxis sensor/effector fusion protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (769 aa)
PA3462Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (919 aa)
PA3346Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (571 aa)
PA3271Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (1159 aa)
PA3206Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (445 aa)
PA3191Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (473 aa)
PA3078Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (431 aa)
PA3044Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (741 aa)
PA2882Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (371 aa)
PA2824Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (786 aa)
pfeSTwo-component sensor PfeS; Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation. (446 aa)
mifSMifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (588 aa)
PA5484Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (595 aa)
phoRTwo-component sensor PhoR; Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. (443 aa)
amgSAmgS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (439 aa)
dctBProbable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity). (612 aa)
ntrBTwo-component sensor NtrB; Product name confidence: Class 2 (High similarity to functionally studied protein). (358 aa)
aruSProbable two-component sensor; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Probably functions as a sensor kinase that phosphorylates AruR. (998 aa)
copSTwo-component sensor, CopS; Member of a two-component regulatory system. (443 aa)
parETopoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (629 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (633 aa)
PA4886Probable two-component sensor; Member of a two-component regulatory system. (463 aa)
retSRetS (Regulator of Exopolysaccharide and Type III Secretion); Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (942 aa)
pmrBPmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (477 aa)
cbrATwo-component sensor CbrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (983 aa)
pilSTwo-component sensor PilS; Member of the two-component regulatory system PilS/PilR involved in the regulation of the expression of type 4 fimbriae. PilS may function as a membrane-associated protein kinase that phosphorylates PilR in response to environmental signals. (530 aa)
roxSRoxS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (422 aa)
PA4398Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (698 aa)
PA4380Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (426 aa)
pprATwo-component sensor PprA; Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae. Modulates also quorum-sensing signal production acting on both negative and positive modulators. Functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to PprB. (922 aa)
bfiSBfiS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (758 aa)
bphPBacterial phytochrome, BphP; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region; In the N-terminal section; belongs to the phytochrome family. (728 aa)
PA4112Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (1417 aa)
bfmSBfmS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (434 aa)
PA4036Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (766 aa)
ladSLost Adherence Sensor, LadS; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (795 aa)
PA1396Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (540 aa)
PA1438Probable two-component sensor; Member of a two-component regulatory system. (481 aa)
PA1458Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (753 aa)
htpGHeat shock protein HtpG; Molecular chaperone. Has ATPase activity. (634 aa)
PA1611Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (651 aa)
parSTwo-component sensor, ParS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (428 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (806 aa)
PA0178Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (639 aa)
chpAComponent of chemotactic signal transduction system; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (2472 aa)
creCTwo-component sensor CreC; Product name confidence: Class 2 (High similarity to functionally studied protein). (474 aa)
PA0600Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (797 aa)
PA0757Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (460 aa)
gacSSensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). (925 aa)
PA0930Two-component sensor; Product name confidence: Class 2 (High similarity to functionally studied protein). (445 aa)
PA1068Probable heat shock protein (hsp90 family); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (636 aa)
fleSTwo-component sensor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (402 aa)
PA1158Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (452 aa)
phoQTwo-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (448 aa)
PA1243Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (858 aa)
PA1336Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (633 aa)
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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