16 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PA2040	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family. (458 aa)
	dctA	C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane. (436 aa)
	spuI	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family. (458 aa)
	spuB	Probable glutamine synthetase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the glutamine synthetase family. (452 aa)
	PA5522	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family. (455 aa)
	PA5508	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family. (443 aa)
	glnK	Nitrogen regulatory protein P-II 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the P(II) protein family. (112 aa)
	amtB	Ammonium transporter AmtB; Product name confidence: Class 2 (High similarity to functionally studied protein). (442 aa)
	dctD	Probable two-component response regulator; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. (462 aa)
	dctB	Probable two-component sensor; Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (By similarity). (612 aa)
	ntrC	Two-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (476 aa)
	glnA	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (469 aa)
	motB	Chemotaxis protein MotB; Product name confidence: Class 2 (High similarity to functionally studied protein). (347 aa)
	rpoN	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (497 aa)
	PA3356	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family. (413 aa)
	PA1566	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family. (454 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA1566	PA2040	PA1566	PA2040	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.629
PA1566	PA3356	PA1566	PA3356	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	0.679
PA1566	PA5508	PA1566	PA5508	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.713
PA1566	PA5522	PA1566	PA5522	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.604
PA1566	amtB	PA1566	PA5287	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Ammonium transporter AmtB; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.776
PA1566	glnA	PA1566	PA5119	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.697
PA1566	glnK	PA1566	PA5288	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Nitrogen regulatory protein P-II 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the P(II) protein family.	0.707
PA1566	ntrC	PA1566	PA5125	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Two-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.	0.607
PA1566	spuB	PA1566	PA0298	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the glutamine synthetase family.	0.677
PA1566	spuI	PA1566	PA0296	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.628
PA2040	PA1566	PA2040	PA1566	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	0.629
PA2040	PA3356	PA2040	PA3356	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the glutamine synthetase family.	0.680
PA2040	PA5508	PA2040	PA5508	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.712
PA2040	PA5522	PA2040	PA5522	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.627
PA2040	amtB	PA2040	PA5287	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Ammonium transporter AmtB; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.775
PA2040	glnA	PA2040	PA5119	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.709
PA2040	glnK	PA2040	PA5288	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Nitrogen regulatory protein P-II 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the P(II) protein family.	0.786
PA2040	ntrC	PA2040	PA5125	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Two-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.	0.607
PA2040	spuB	PA2040	PA0298	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the glutamine synthetase family.	0.677
PA2040	spuI	PA2040	PA0296	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	Probable glutamine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the glutamine synthetase family.	0.602