10 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Your Input:
	pilY1	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity). (1161 aa)
	pilW	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (274 aa)
	pilO	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (207 aa)
	pilQ	Type 4 fimbrial biogenesis outer membrane protein PilQ precursor; Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a 'porthole' allowing passage of the fimbrae through the outer membrane; Belongs to the bacterial secretin family. PilQ subfamily. (714 aa)
	fimT	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (169 aa)
	pilZ	Type 4 fimbrial biogenesis protein PilZ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (118 aa)
	pilJ	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (682 aa)
	pilU	Twitching motility protein PilU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (382 aa)
	pilM	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (354 aa)
	pilN	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (198 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fimT	pilJ	PA4549	PA0411	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	0.445
fimT	pilM	PA4549	PA5044	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.851
fimT	pilN	PA4549	PA5043	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.863
fimT	pilO	PA4549	PA5042	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.856
fimT	pilQ	PA4549	PA5040	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis outer membrane protein PilQ precursor; Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a 'porthole' allowing passage of the fimbrae through the outer membrane; Belongs to the bacterial secretin family. PilQ subfamily.	0.854
fimT	pilU	PA4549	PA0396	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Twitching motility protein PilU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.754
fimT	pilW	PA4549	PA4552	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.977
fimT	pilY1	PA4549	PA4554	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).	0.978
fimT	pilZ	PA4549	PA2960	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilZ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.686
pilJ	fimT	PA0411	PA4549	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.445
pilJ	pilM	PA0411	PA5044	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.966
pilJ	pilN	PA0411	PA5043	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.937
pilJ	pilO	PA0411	PA5042	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.896
pilJ	pilQ	PA0411	PA5040	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis outer membrane protein PilQ precursor; Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a 'porthole' allowing passage of the fimbrae through the outer membrane; Belongs to the bacterial secretin family. PilQ subfamily.	0.959
pilJ	pilU	PA0411	PA0396	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Twitching motility protein PilU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.909
pilJ	pilW	PA0411	PA4552	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.846
pilJ	pilY1	PA0411	PA4554	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).	0.823
pilJ	pilZ	PA0411	PA2960	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	Type 4 fimbrial biogenesis protein PilZ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.896
pilM	fimT	PA5044	PA4549	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein FimT; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.851
pilM	pilJ	PA5044	PA0411	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Twitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).	0.966