STRINGSTRING
pilH pilH flgG flgG pcs pcs pilD pilD pilV pilV pilQ pilQ pilP pilP pilU pilU pilT pilT pilJ pilJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pilHTwitching motility protein PilH; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (121 aa)
flgGFlagellar basal-body rod protein FlgG; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the flagella basal body rod proteins family. (261 aa)
pcsPhosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (238 aa)
pilDType 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. Processes the pilin precursor during membrane translocation. Required for the assembly of type IV pili and for secretion of most proteins. (290 aa)
pilVType 4 fimbrial biogenesis protein PilV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (185 aa)
pilQType 4 fimbrial biogenesis outer membrane protein PilQ precursor; Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a 'porthole' allowing passage of the fimbrae through the outer membrane; Belongs to the bacterial secretin family. PilQ subfamily. (714 aa)
pilPType 4 fimbrial biogenesis protein PilP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (174 aa)
pilUTwitching motility protein PilU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (382 aa)
pilTTwitching motility protein PilT; May be involved in pilus retraction; Belongs to the GSP E family. (344 aa)
pilJTwitching motility protein PilJ; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (682 aa)
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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