STRINGSTRING
bamB bamB tufA tufA tufB tufB purU1 purU1 pykA pykA PA4578 PA4578 PA4607 PA4607 mscL mscL pagL pagL phhB phhB oprH oprH phoP phoP pykF pykF PA1288 PA1288 mliC mliC fimV fimV purL purL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bamBConserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (380 aa)
tufAElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
tufBElongation factor Tu; Product name confidence: Class 2 (High similarity to functionally studied protein). (397 aa)
purU1Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa)
pykAPyruvate kinase II; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the pyruvate kinase family. (483 aa)
PA4578Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (162 aa)
PA4607Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (168 aa)
mscLConductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (137 aa)
pagLLipid A 3-O-deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety. Lacks fatty acyl chain-length specificity as removes both 3-OH C10 and 3-OH C14 fatty acids from lipid A. (173 aa)
phhBPterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. (118 aa)
oprHPhoP/Q and low Mg2+ inducible outer membrane protein H1 precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (200 aa)
phoPTwo-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (225 aa)
pykFPyruvate kinase I; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the pyruvate kinase family. (477 aa)
PA1288Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (424 aa)
mliCMembrane-bound lysozyme inhibitor of c-type lysozyme MliC; Specifically inhibits C-type lysozymes. (127 aa)
fimVMotility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (919 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1298 aa)
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
Server load: low (20%) [HD]