11 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	cheD	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (200 aa)
	aer2	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (679 aa)
	cyaA	Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). (950 aa)
	cheR2	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (280 aa)
	aer	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein). (521 aa)
	cheZ	Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (262 aa)
	chpB	Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (343 aa)
	pilH	Twitching motility protein PilH; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). (121 aa)
	polB	DNA polymerase II; Product name confidence: Class 2 (High similarity to functionally studied protein). (787 aa)
	cheR1	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (274 aa)
	ampR	Transcriptional regulator AmpR; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. (296 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aer	aer2	PA1561	PA0176	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.562
aer	cheD	PA1561	PA0174	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	0.961
aer	cheR1	PA1561	PA3348	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.989
aer	cheR2	PA1561	PA0175	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.983
aer	cheZ	PA1561	PA1457	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).	0.827
aer	chpB	PA1561	PA0414	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.	0.792
aer2	aer	PA0176	PA1561	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.562
aer2	cheD	PA0176	PA0174	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	0.994
aer2	cheR1	PA0176	PA3348	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.971
aer2	cheR2	PA0176	PA0175	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.999
aer2	cheZ	PA0176	PA1457	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).	0.731
aer2	chpB	PA0176	PA0414	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.	0.915
cheD	aer	PA0174	PA1561	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.961
cheD	aer2	PA0174	PA0176	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.994
cheD	cheR1	PA0174	PA3348	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.754
cheD	cheR2	PA0174	PA0175	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	0.993
cheD	chpB	PA0174	PA0414	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.	0.823
cheR1	aer	PA3348	PA1561	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.989
cheR1	aer2	PA3348	PA0176	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.971
cheR1	cheD	PA3348	PA0174	Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.	Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.	0.754