node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroP2 | hmgA | PA0866 | PA2009 | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.721 |
aroP2 | hpd | PA0866 | PA0865 | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.925 |
aroP2 | phhB | PA0866 | PA0871 | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 0.490 |
aroP2 | phhR | PA0866 | PA0873 | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.428 |
hmgA | aroP2 | PA2009 | PA0866 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.721 |
hmgA | hpd | PA2009 | PA0865 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.999 |
hmgA | phhB | PA2009 | PA0871 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 0.921 |
hmgA | phhR | PA2009 | PA0873 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.807 |
hpd | aroP2 | PA0865 | PA0866 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.925 |
hpd | hmgA | PA0865 | PA2009 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.999 |
hpd | phhB | PA0865 | PA0871 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 0.916 |
hpd | phhR | PA0865 | PA0873 | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.837 |
phhB | aroP2 | PA0871 | PA0866 | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.490 |
phhB | hmgA | PA0871 | PA2009 | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.921 |
phhB | hpd | PA0871 | PA0865 | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.916 |
phhB | phhR | PA0871 | PA0873 | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.874 |
phhR | aroP2 | PA0873 | PA0866 | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Aromatic amino acid transport protein AroP2; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.428 |
phhR | hmgA | PA0873 | PA2009 | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.807 |
phhR | hpd | PA0873 | PA0865 | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 4-hydroxyphenylpyruvate dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the 4HPPD family. | 0.837 |
phhR | phhB | PA0873 | PA0871 | Transcriptional regulator PhhR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA. | 0.874 |