7 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fimV	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (919 aa)
	cyaB	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (463 aa)
	bifA	BifA; Class 1: Function experimentally demonstrated in P. aeruginosa. (687 aa)
	exoT	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (457 aa)
	vfr	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. (214 aa)
	exsA	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level. (278 aa)
	PA2990	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (240 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA2990	bifA	PA2990	PA4367	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	BifA; Class 1: Function experimentally demonstrated in P. aeruginosa.	0.883
PA2990	cyaB	PA2990	PA3217	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.736
PA2990	vfr	PA2990	PA0652	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	0.538
bifA	PA2990	PA4367	PA2990	BifA; Class 1: Function experimentally demonstrated in P. aeruginosa.	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.883
cyaB	PA2990	PA3217	PA2990	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.736
cyaB	exsA	PA3217	PA1713	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	0.595
cyaB	fimV	PA3217	PA3115	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.844
cyaB	vfr	PA3217	PA0652	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	0.995
exoT	exsA	PA0044	PA1713	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	0.971
exoT	vfr	PA0044	PA0652	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	0.413
exsA	cyaB	PA1713	PA3217	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.595
exsA	exoT	PA1713	PA0044	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.971
exsA	vfr	PA1713	PA0652	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	0.883
fimV	cyaB	PA3115	PA3217	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.844
fimV	vfr	PA3115	PA0652	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	0.850
vfr	PA2990	PA0652	PA2990	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	Probable phosphodiesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.538
vfr	cyaB	PA0652	PA3217	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.995
vfr	exoT	PA0652	PA0044	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.413
vfr	exsA	PA0652	PA1713	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.	0.883
vfr	fimV	PA0652	PA3115	Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.850