6 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lpxA	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
	pmrB	PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (477 aa)
	pmrA	PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (221 aa)
	lpxC	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (303 aa)
	phoQ	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (448 aa)
	phoP	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (225 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
lpxA	lpxC	PA3644	PA4406	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.998
lpxA	phoP	PA3644	PA1179	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.763
lpxA	phoQ	PA3644	PA1180	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.738
lpxA	pmrA	PA3644	PA4776	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.885
lpxA	pmrB	PA3644	PA4777	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.885
lpxC	lpxA	PA4406	PA3644	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.998
lpxC	phoP	PA4406	PA1179	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.713
lpxC	phoQ	PA4406	PA1180	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.644
lpxC	pmrA	PA4406	PA4776	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.885
lpxC	pmrB	PA4406	PA4777	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.884
phoP	lpxA	PA1179	PA3644	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.763
phoP	lpxC	PA1179	PA4406	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.713
phoP	phoQ	PA1179	PA1180	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.999
phoP	pmrA	PA1179	PA4776	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.673
phoP	pmrB	PA1179	PA4777	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.986
phoQ	lpxA	PA1180	PA3644	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.738
phoQ	lpxC	PA1180	PA4406	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.644
phoQ	phoP	PA1180	PA1179	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Two-component response regulator PhoP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.999
phoQ	pmrA	PA1180	PA4776	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.955
phoQ	pmrB	PA1180	PA4777	Two-component sensor PhoQ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.479