11 items (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pilY1	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity). (1161 aa)
	pilM	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (354 aa)
	pilN	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (198 aa)
	pilO	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (207 aa)
	gltB	Glutamate synthase large chain precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). (1481 aa)
	fimV	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (919 aa)
	pilF	Type 4 fimbrial biogenesis protein PilF; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (252 aa)
	ftsI	Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin. (579 aa)
	fimU	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (168 aa)
	pilW	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (274 aa)
	pilX	Type 4 fimbrial biogenesis protein PilX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (195 aa)

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fimU	fimV	PA4550	PA3115	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.542
fimU	pilF	PA4550	PA3805	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilF; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.773
fimU	pilM	PA4550	PA5044	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.877
fimU	pilN	PA4550	PA5043	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.873
fimU	pilO	PA4550	PA5042	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.895
fimU	pilW	PA4550	PA4552	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.999
fimU	pilX	PA4550	PA4553	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.998
fimU	pilY1	PA4550	PA4554	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).	0.999
fimV	fimU	PA3115	PA4550	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.542
fimV	pilF	PA3115	PA3805	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilF; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.828
fimV	pilM	PA3115	PA5044	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.936
fimV	pilN	PA3115	PA5043	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.953
fimV	pilO	PA3115	PA5042	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.942
fimV	pilW	PA3115	PA4552	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilW; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.430
fimV	pilX	PA3115	PA4553	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilX; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.480
fimV	pilY1	PA3115	PA4554	Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).	0.792
gltB	pilM	PA5036	PA5044	Glutamate synthase large chain precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).	Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.473
gltB	pilN	PA5036	PA5043	Glutamate synthase large chain precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).	Type 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.475
gltB	pilO	PA5036	PA5042	Glutamate synthase large chain precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).	Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.475
pilF	fimU	PA3805	PA4550	Type 4 fimbrial biogenesis protein PilF; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	Type 4 fimbrial biogenesis protein FimU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.773