STRINGSTRING
bcrA bcrA greA greA valS valS AOD25023.1 AOD25023.1 AOD25021.1 AOD25021.1 AOD25020.1 AOD25020.1 gidA gidA AOD25017.1 AOD25017.1 dnaN dnaN AOD25704.1 AOD25704.1 AOD25703.1 AOD25703.1 nrdE nrdE nrdI nrdI AOD25687.1 AOD25687.1 atpD-2 atpD-2 AOD25684.1 AOD25684.1 whiA whiA uvrB uvrB AOD25675.1 AOD25675.1 fpg fpg oppA-2 oppA-2 oppD oppD oppF oppF dnaI dnaI AOD25655.1 AOD25655.1 AOD25653.1 AOD25653.1 gap gap dnaK dnaK tdk tdk AOD25638.1 AOD25638.1 thrS thrS trpS trpS AOD25630.1 AOD25630.1 pyrH pyrH polC polC AOD25612.1 AOD25612.1 trmE trmE gatB gatB AOD25595.1 AOD25595.1 AOD25594.1 AOD25594.1 secA secA upp upp AOD25586.1 AOD25586.1 tuf tuf AOD25584.1 AOD25584.1 clpB clpB rbgA rbgA pfkA pfkA AOD25565.1 AOD25565.1 pheS pheS pheT pheT truB truB AOD25559.1 AOD25559.1 alaS alaS tilS tilS hflB hflB lysS lysS rpsF rpsF AOD25546.1 AOD25546.1 rpsR rpsR gtp1 gtp1 AOD25542.1 AOD25542.1 rplT rplT pdhD pdhD nadE nadE AOD25529.1 AOD25529.1 AOD25526.1 AOD25526.1 AOD25524.1 AOD25524.1 fusA fusA rpsG rpsG rpsL rpsL smc smc rnc rnc nusA nusA cysS cysS infB infB AOD25506.1 AOD25506.1 AOD25503.1 AOD25503.1 dprA dprA rplU rplU proS proS potA potA rnr rnr AOD25485.1 AOD25485.1 AOD25465.1 AOD25465.1 rnhC rnhC AOD25462.1 AOD25462.1 uvrA uvrA AOD25456.1 AOD25456.1 pgk pgk AOD25451.1 AOD25451.1 gmk gmk rsgA rsgA rpsT rpsT scpB scpB tsf tsf ffh ffh glyS glyS dnaG dnaG rpoD rpoD nfo nfo AOD25423.1 AOD25423.1 AOD25422.1 AOD25422.1 rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsZ rpsZ rpsH rpsH AOD25348.1 AOD25348.1 AOD25347.1 AOD25347.1 nusG nusG gyrB gyrB metK metK smpB smpB pacL pacL ruvB ruvB ruvA ruvA AOD25320.1 AOD25320.1 asnC asnC rplK rplK rplA rplA pyrG pyrG AOD25307.1 AOD25307.1 AOD25306.1 AOD25306.1 topA topA nadD nadD ackA ackA engB engB AOD25285.1 AOD25285.1 AOD25282.1 AOD25282.1 AOD25280.1 AOD25280.1 AOD25278.1 AOD25278.1 era era rpmE rpmE acpD acpD AOD25270.1 AOD25270.1 AOD25268.1 AOD25268.1 prfA prfA AOD25266.1 AOD25266.1 gltX gltX AOD25263.1 AOD25263.1 AOD25262.1 AOD25262.1 AOD25257.1 AOD25257.1 metG metG AOD25251.1 AOD25251.1 AOD25238.1 AOD25238.1 gpsA gpsA mraZ mraZ AOD25232.1 AOD25232.1 AOD25230.1 AOD25230.1 AOD25227.1 AOD25227.1 AOD25226.1 AOD25226.1 oppD-1 oppD-1 efp efp rluD rluD AOD25212.1 AOD25212.1 AOD25211.1 AOD25211.1 AOD25210.1 AOD25210.1 malK malK AOD25201.1 AOD25201.1 AOD25200.1 AOD25200.1 AOD25199.1 AOD25199.1 AOD25194.1 AOD25194.1 AOD25193.1 AOD25193.1 AOD25190.1 AOD25190.1 AOD25188.1 AOD25188.1 AOD25186.1 AOD25186.1 AOD25185.1 AOD25185.1 AOD25184.1 AOD25184.1 AOD25172.1 AOD25172.1 AOD25168.1 AOD25168.1 glyA glyA rpsO rpsO serS serS AOD25160.1 AOD25160.1 AOD25159.1 AOD25159.1 aspS aspS hisS hisS AOD25151.1 AOD25151.1 ileS ileS uvrC uvrC parC parC parE parE rplF rplF rplR rplR rpsE rpsE rplO rplO adk adk infA infA rpsM rpsM rpsK rpsK rpoA rpoA recA recA obg obg dinP dinP atpA atpA atpG atpG atpD-1 atpD-1 AOD25359.1 AOD25359.1 AOD25358.1 AOD25358.1 leuS leuS AOD25355.1 AOD25355.1 rplI rplI dnaC dnaC AOD25352.1 AOD25352.1 AOD25351.1 AOD25351.1 vlpA vlpA AOD25208.1 AOD25208.1 dhfR dhfR recU recU rnpA rnpA AOD25705.1 AOD25705.1 gtsA gtsA ksgA ksgA prs prs tyrS tyrS gyrA gyrA ecfA ecfA cbiO cbiO AOD25116.1 AOD25116.1 tmk tmk recR recR AOD25111.1 AOD25111.1 dnaX dnaX AOD25107.1 AOD25107.1 AOD25105.1 AOD25105.1 argS argS grpE grpE hrcA hrcA AOD25094.1 AOD25094.1 ftsY ftsY rpsD rpsD tmcAL tmcAL AOD25084.1 AOD25084.1 lepA lepA AOD25079.1 AOD25079.1 engA engA cmk cmk AOD25074.1 AOD25074.1 AOD25071.1 AOD25071.1 rpoC rpoC rpoB rpoB rplJ rplJ holA holA AOD25060.1 AOD25060.1 AOD25059.1 AOD25059.1 AOD25054.1 AOD25054.1 AOD25053.1 AOD25053.1 AOD25052.1 AOD25052.1 nox nox mnmA mnmA dnaJ dnaJ AOD25040.1 AOD25040.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
bcrAABC-type multidrug-like transport system ATP-binding protein; Identified by sequence similarity; putative. (238 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (164 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (824 aa)
AOD25023.1Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative. (458 aa)
AOD25021.1DHH family protein; Identified by sequence similarity; putative. (321 aa)
AOD25020.1DHHA1 domain protein; Identified by sequence similarity; putative. (325 aa)
gidAtRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (619 aa)
AOD25017.1S4-like RNA binding protein; Identified by sequence similarity; putative. (71 aa)
dnaNDNA polymerase III, beta subunit; Identified by sequence similarity; putative. (374 aa)
AOD25704.1ATPase AAA2 domain protein; Identified by sequence similarity; putative. (45 aa)
AOD25703.1CLP-like protein; Identified by sequence similarity; putative. (332 aa)
nrdERibonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (721 aa)
nrdIRibonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function. (153 aa)
AOD25687.1F0F1 ATP synthase subunit alpha; Identified by sequence similarity; putative. (507 aa)
atpD-2ATP synthase F1, beta subunit-2; Identified by sequence similarity; putative. (464 aa)
AOD25684.1ABC transporter ATP-binding-Pr1 protein; Identified by sequence similarity; putative. (215 aa)
whiAHypothetical protein; Involved in cell division and chromosome segregation. (281 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (653 aa)
AOD25675.1Sua5/YciO/YrdC/YwlC family protein; Identified by sequence similarity; putative; Belongs to the SUA5 family. (243 aa)
fpgformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (278 aa)
oppA-2Oligopeptide ABC transporter, substrate-binding lipoprotein OppA; Identified by sequence similarity; putative. (946 aa)
oppDOligopeptide ABC transporter ATP binding prote; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (354 aa)
oppFOligopeptide transport system permease protein; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (767 aa)
dnaIPutative primosomal protein; Identified by sequence similarity; putative. (289 aa)
AOD25655.1Putative ABC transporter ATP-binding protein p29; Identified by sequence similarity; putative. (252 aa)
AOD25653.1Mobile element protein; Identified by sequence similarity; putative. (357 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase C; Identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
dnaKHsp70-like protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. (597 aa)
tdkThymidine kinase; Identified by sequence similarity; putative. (192 aa)
AOD25638.1Transposase, IS861; Identified by sequence similarity; putative. (239 aa)
thrSThreonyl-tRNA synthetase; Identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. (581 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (327 aa)
AOD25630.1Putative ATP-binding helicase; Identified by sequence similarity; putative. (1048 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa)
polCDNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1457 aa)
AOD25612.1ABC transporter, ATP-binding protein; Identified by sequence similarity; putative. (538 aa)
trmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (444 aa)
gatBAsp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (474 aa)
AOD25595.1Ribosomal large subunit pseudouridine synthase C; Identified by sequence similarity; putative; Belongs to the pseudouridine synthase RluA family. (289 aa)
AOD25594.1IS1221 transposase; Identified by sequence similarity; putative. (488 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (898 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
AOD25586.1ATPase AAA; Identified by sequence similarity; putative. (864 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (402 aa)
AOD25584.1Mobile element protein; Identified by sequence similarity; putative. (357 aa)
clpBATP-dependent chaperone ClpB; Identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. (703 aa)
rbgAGTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (284 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
AOD25565.1Recombination factor protein RarA; Identified by sequence similarity; putative. (405 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (318 aa)
pheTphenylalanyl-tRNA synthetase, beta subunit; Identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (728 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (288 aa)
AOD25559.1Cytidyltransferase family protein; Identified by sequence similarity; putative. (290 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (887 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (292 aa)
hflBATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (726 aa)
lysSlysyl-tRNA synthetase; Identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. (492 aa)
rpsFSSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA. (182 aa)
AOD25546.1Single-stranded DNA-binding protein; Identified by sequence similarity; putative. (179 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (80 aa)
gtp1Putative GTPase, putative translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa)
AOD25542.1Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (230 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
pdhDDihydrolipoamide dehydrogenase; Identified by sequence similarity; putative. (629 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (243 aa)
AOD25529.1Putative DNA-binding regulatory protein; Identified by sequence similarity; putative. (242 aa)
AOD25526.1Pyruvate kinase; Identified by sequence similarity; putative; Belongs to the pyruvate kinase family. (475 aa)
AOD25524.1Transposase, IS861; Identified by sequence similarity; putative. (384 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (695 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLSSU ribosomal protein S12p; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (139 aa)
smcChromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (979 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (225 aa)
nusATranscription termination factor NusA; Identified by sequence similarity; putative. (538 aa)
cysSCysteinyl-tRNA synthetase; Identified by sequence similarity; putative. (400 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (604 aa)
AOD25506.15'-3' exonuclease family protein; Identified by sequence similarity; putative. (296 aa)
AOD25503.1TraE/TrsE-like membrane protein; Identified by sequence similarity; putative. (887 aa)
dprADNA processing protein, DprA; Identified by sequence similarity; putative. (254 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (99 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa)
potASpermidine/putrescine ABC transporter ATP-binding protein; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (446 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (694 aa)
AOD25485.1ABC transporter, ATP-binding protein; Identified by sequence similarity; putative. (237 aa)
AOD25465.1Transposase, IS861; Identified by sequence similarity; putative. (257 aa)
rnhCRibonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (240 aa)
AOD25462.1Metallo-beta-lactamase superfamily protein; Identified by sequence similarity; putative. (591 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (955 aa)
AOD25456.1Transposase, IS861; Identified by sequence similarity; putative. (203 aa)
pgkPhosphoglycerate kinase; Identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. (402 aa)
AOD25451.1Hypothetical protein; Identified by sequence similarity; putative; Expressed protein. (197 aa)
gmkGuanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. (192 aa)
rsgAPutative ribosome biogenesis GTPase rsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (284 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (90 aa)
scpBSegregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (203 aa)
tsfElongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (296 aa)
ffhSignal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (445 aa)
glySGlycyl-tRNA synthetase; Identified by sequence similarity; putative. (458 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (595 aa)
rpoDRNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (524 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (275 aa)
AOD25423.1Transposase, IS861; Identified by sequence similarity; putative. (302 aa)
AOD25422.1Transposase InsK; Identified by sequence similarity; putative. (139 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (104 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (231 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (295 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (164 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (281 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (121 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (243 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (100 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa)
rplXRibosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (106 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (181 aa)
rpsZ30S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
AOD25348.1RNA methyltransferase, TrmH family; Identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (225 aa)
AOD25347.1Hypothetical protein; Identified by sequence similarity; putative; Belongs to the sigma-70 factor family. (182 aa)
nusGTranscription antitermination protein; Participates in transcription elongation, termination and antitermination. (198 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (640 aa)
metKS-adenosylmethionine synthetase; Identified by sequence similarity; putative; Belongs to the AdoMet synthase family. (380 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (145 aa)
pacLCation transporting P type ATPase; Identified by sequence similarity; putative. (899 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (317 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (213 aa)
AOD25320.1ATP-dependent helicase PcrA; Identified by sequence similarity; putative. (751 aa)
asnCasparaginyl-tRNA synthetase; Identified by sequence similarity; putative. (446 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (150 aa)
rplALSU ribosomal protein L1p; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (545 aa)
AOD25307.1Oxidoreductase, FAD/FMN-binding protein; Identified by sequence similarity; putative. (398 aa)
AOD25306.1Lipoate-protein ligase A; Identified by sequence similarity; putative. (346 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (617 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (364 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
engBGTPase EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (184 aa)
AOD25285.1Ribosomal large subunit pseudouridine synthase B; Identified by sequence similarity; putative; Belongs to the pseudouridine synthase RsuA family. (242 aa)
AOD25282.1Putative rRNA methyltransferase; Identified by sequence similarity; putative. (238 aa)
AOD25280.1Transcription termination factor; Identified by sequence similarity; putative. (152 aa)
AOD25278.1ABC transporter ATP-binding and permease protein; Identified by sequence similarity; putative. (676 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (292 aa)
rpmERibosomal protein L31; Identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL31 family. (73 aa)
acpDFMN-dependent NADH-azoreductase; Identified by sequence similarity; putative. (201 aa)
AOD25270.1Putative quinone reductase; Identified by sequence similarity; putative. (194 aa)
AOD25268.1ABC transporter ATP-binding protein; Identified by sequence similarity; putative. (311 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (383 aa)
AOD25266.1Methyltransferase, HemK family; Identified by sequence similarity; putative. (243 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (481 aa)
AOD25263.1RNA methyltransferase, TrmH family; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (175 aa)
AOD25262.1rRNA methylase; Identified by sequence similarity; putative. (256 aa)
AOD25257.1Type I restriction-modification system methyltransferase subunit; Identified by sequence similarity; putative. (906 aa)
metGmethionyl-tRNA synthetase; Identified by sequence similarity; putative. (510 aa)
AOD25251.1Methyltransferase small domain protein; Identified by sequence similarity; putative; Belongs to the methyltransferase superfamily. (257 aa)
AOD25238.1Mobile element protein; Identified by sequence similarity; putative. (138 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Identified by sequence similarity; putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
mraZProtein mraZ; Identified by sequence similarity; putative; Belongs to the MraZ family. (147 aa)
AOD25232.1Cell division protein FtsZ; Identified by sequence similarity; putative. (374 aa)
AOD25230.1Putative integrase/recombinase ripx; Identified by sequence similarity; putative; Belongs to the 'phage' integrase family. (307 aa)
AOD25227.1Hypothetical protein. (2756 aa)
AOD25226.1Oligopeptide transport ATP-binding protein OppF; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (448 aa)
oppD-1Oligopeptide ABC transporter, ATP-binding protein; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (481 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
rluDRibosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (294 aa)
AOD25212.1Putative ABC transporter ATP-binding - Pr2; Identified by sequence similarity; putative. (343 aa)
AOD25211.1Transporter ATP-binding protein/permease; Identified by sequence similarity; putative. (193 aa)
AOD25210.1ABC transporter, ATP-binding/permease protein; Identified by sequence similarity; putative. (528 aa)
malKMaltodextrin ABC transporter, ATP-binding protein; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (414 aa)
AOD25201.1Transposase, IS861; Identified by sequence similarity; putative. (353 aa)
AOD25200.1Transposase; Identified by sequence similarity; putative. (117 aa)
AOD25199.1GntR-family transcriptional regulator; Identified by sequence similarity; putative. (237 aa)
AOD25194.1Transposase, IS861; Identified by sequence similarity; putative. (147 aa)
AOD25193.1AAA family ATPase; Identified by sequence similarity; putative. (349 aa)
AOD25190.1Type III restriction-modification system: methylase; Identified by sequence similarity; putative. (401 aa)
AOD25188.1Putative type III restriction-modification system: methylase; Identified by sequence similarity; putative. (369 aa)
AOD25186.1Site-specific DNA-methyltransferase, Adenine-specific; Identified by sequence similarity; putative. (374 aa)
AOD25185.1Type III restriction enzyme, res subunit; Identified by sequence similarity; putative. (810 aa)
AOD25184.1Transposase InsK; Identified by sequence similarity; putative. (305 aa)
AOD25172.1ABC transporter, ATP-binding protein; Identified by sequence similarity; putative. (512 aa)
AOD25168.1Transposase, IS861; Identified by sequence similarity; putative. (203 aa)
glyASerine hydroxymethyltransferase 3; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (88 aa)
serSseryl-tRNA synthetase; Identified by sequence similarity; putative. (422 aa)
AOD25160.1ABC-type multidrug transport system, ATPase and permease component; Identified by sequence similarity; putative. (538 aa)
AOD25159.1ABC transporter, ATP-binding/permease protein; Identified by sequence similarity; putative. (538 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (573 aa)
hisShistidyl-tRNA synthetase; Identified by sequence similarity; putative. (438 aa)
AOD25151.1IS1221 transposase; Identified by sequence similarity; putative. (474 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (892 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (561 aa)
parCDNA topoisomerase IV subunit A; Identified by sequence similarity; putative. (888 aa)
parEDNA topoisomerase IV subunit B; Identified by sequence similarity; putative. (649 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (183 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (123 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (223 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa)
infABacterial translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (333 aa)
recARecombinase protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (328 aa)
obgGTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (418 aa)
dinPDNA polymerase IV; Identified by sequence similarity; putative. (396 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (508 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (282 aa)
atpD-1ATP synthase F1, beta subunit-1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (470 aa)
AOD25359.1Transposase InsK; Identified by sequence similarity; putative. (164 aa)
AOD25358.1Transposase, IS861; Identified by sequence similarity; putative. (133 aa)
leuSleucyl-tRNA synthetase; Identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (788 aa)
AOD25355.1DHHA1 domain protein; Identified by sequence similarity; putative. (664 aa)
rplIRibosomal protein L9; Binds to the 23S rRNA. (145 aa)
dnaCReplicative helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (457 aa)
AOD25352.1CBS domain protein; Identified by sequence similarity; putative. (413 aa)
AOD25351.1Hypothetical protein; Identified by sequence similarity; putative; Expressed protein. (229 aa)
vlpAVariant surface antigen A; Identified by sequence similarity; putative. (233 aa)
AOD25208.1Type I restriction-modification system, specificity subunit S; Identified by sequence similarity; putative. (151 aa)
dhfRDihydrofolate reductase; Identified by sequence similarity; putative; Belongs to the dihydrofolate reductase family. (159 aa)
recURecombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (162 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (116 aa)
AOD25705.1Hypothetical protein. (209 aa)
gtsAGlycerol ABC transporter, ATP bindingcomponent; Identified by sequence similarity; putative. (412 aa)
ksgA16S ribosomal rRNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (257 aa)
prsRibose-phosphate pyrophosphokinase; Identified by sequence similarity; putative. (326 aa)
tyrSTyrosyl tRNA synthetase 1; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (877 aa)
ecfAABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (304 aa)
cbiOABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (266 aa)
AOD25116.1Hypoxanthine-guanine phosphoribosyltransferase; Identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa)
recRRecombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (190 aa)
AOD25111.1UPF0133 protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (95 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (712 aa)
AOD25107.1Lipoate-protein ligase A; Identified by sequence similarity; putative. (329 aa)
AOD25105.1Mobile element protein; Identified by sequence similarity; putative. (203 aa)
argSarginyl-tRNA synthetase; Identified by sequence similarity; putative. (533 aa)
grpEHeat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] (260 aa)
hrcAHeat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (352 aa)
AOD25094.1Putative UPF0122 protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (79 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (380 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
tmcALUPF0348 protein family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (304 aa)
AOD25084.1ABC transporter, ATP-binding protein; Identified by sequence similarity; putative. (512 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa)
AOD25079.1Integration host factor alpha/beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
engAGTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa)
cmkCytidylate kinase; Identified by sequence similarity; putative. (222 aa)
AOD25074.1ATP-binding protein of ABC transporter; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (631 aa)
AOD25071.1Dihydrofolate reductase; Identified by sequence similarity; putative; Belongs to the dihydrofolate reductase family. (159 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1236 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa)
holADNA polymerase III, delta subunit; Identified by sequence similarity; putative. (310 aa)
AOD25060.1Putative 5' nucleotidase; Identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family. (693 aa)
AOD25059.1Transposase, IS861; Identified by sequence similarity; putative. (358 aa)
AOD25054.1ABC transporter ATP-binding protein; Identified by sequence similarity; putative. (262 aa)
AOD25053.1Putative transmembrane ATP-binding protein; Identified by sequence similarity; putative. (267 aa)
AOD25052.1ABC transporter, ATP-binding and permease component; Identified by sequence similarity; putative. (536 aa)
noxNADH oxidase; Identified by sequence similarity; putative. (458 aa)
mnmAtRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (370 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (372 aa)
AOD25040.1ABC transporter, ATP-binding protein; Identified by sequence similarity; putative. (246 aa)
Your Current Organism:
Mycoplasma hyorhinis
NCBI taxonomy Id: 2100
Other names: ATCC 17981, ATCC 23234, Asterococcus hyorhinis, CIP 104968, DSM 25591, IFO 14858, M. hyorhinis, NBRC 14858, NCTC 10130, strain BTS 7, strain BTS-7, strain BTS7, strain PG42
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